Herbicidal sulfonamides

ABSTRACT

Certain sulfonylurea compounds such as 2-[[[4-methoxy-6-(methylselenylmethyl)pyrimidin-2-yl]aminocarbonyl]ami nosulfonyl]benzoic acid, methyl ester and 2-[[[4-methoxy-6-(phenylthiomethyl)pyrimidin-2-yl]-aminocarbonyl]amino sulfonyl]benzoic acid, methyl ester provide herbicidal activity.

BACKGROUND OF THE INVENTION

The present invention relates to a class of sulfonylurea compounds,agriculturally suitable compositions containing them and theirmethod-of-use as pre-emergent and/or post-emergent herbicides or plantgrowth regulants.

Sulfonylurea compounds exhibiting herbicidal activity are disclosed inU.S. Pat. Nos. 4,127,405 and 4,169,719. Herbicidal benzenesulfonylureacompounds containing an ortho-carboxy ester group are disclosed in U.S.Pat. No. 4,383,113.

European Application No. 84,224, published July 27, 1983 disclosesherbicidal sulfonylureas such as ##STR1##

European Application No. 9419 published Apr. 2, 1980 disclosesherbicidal sulfonylureas such as ##STR2## where ##STR3## R₄ is Cl, Br,F, NO₂, CH₃, OCH₃, CF₃ or S(O)_(n) R₃ ;

X is CH₃ or OCH₃ ; and

Y is CH₂ F, CH₂ Cl, CH₂ Br, C₂ -C₄ alkenyl, etc.

SUMMARY OF THE INVENTION

This invention relates to novel compounds of Formula I, agriculturallysuitable compositions containing them and their method-of-use aspre-emergent and/or post-emergent herbicides or plant growth regulants.##STR4## wherein R is H or CH₃ ; ##STR5## R₁ is C₁ -C₄ alkyl, C₁ -C₄alkoxy, OCH₂ CH₂ OCH₃, F, Cl, Br, NO₂, CF₃, CO₂ R₁₅, SO₂ NR₁₆ R₁₇, SO₂N(OCH₃)CH₃, OSO₂ R₁₈, S(O)_(n) R₁₉, WCF₃, WCHF₂, C₃ -C₄ alkenyloxy, C₃-C₄ alkynyloxy, C₆ H₅, C₁ -C₂ alkyl substituted with OCH₃ or OCH₂ CH₃,##STR6## R₂ is H, F, Cl, Br, CF₃, CH₃, OCH₃ or SCH₃ ; R₃ is H, CH₃,OCH₃, F, Cl, Br, SO₂ N(CH₃)₂, OSO₂ CH₃ or S(O)_(n) CH₃ ;

R₄ is CH₃, CH₂ CH₃, OCH₃, OCH₂ CH₃, F, Cl, Br, SO₂ NR₁₆ R₁₇, SO₂N(OCH₃)CH₃ or S(O)_(n) R₁₉ ;

R₅ is C₁ -C₃ alkyl, F, Cl, Br, NO₂, CO₂ R₁₅, SO₂ NR₁₆ R₁₇, SO₂N(OCH₃)CH₃ or S(O)_(n) R₁₉ ;

R₆ is Cl, NO₂, CO₂ CH₃, CO₂ CH₂ CH₃, SO₂ N(CH₃)₂, OSO₂ CH₃, SO₂ CH₃, SO₂CH₂ CH₃, OCH₃ or OCH₂ CH₃ ;

R₇ is H, CH₃ or CH₂ CH₃ ;

R₈ is H, CH₃ or CH₂ CH₃ ;

R₉ is H or CH₃ ;

R₁₀ is H or CH₃ ;

R₁₁ is H or CH₃ ;

R₁₂ is C₁ -C₃ alkyl;

R₁₃ is H or C₁ -C₃ alkyl;

R₁₄ is H or CH₃ ;

R₁₅ is C₁ -C₄ alkyl, CH₂ CH₂ OCH₃, CH₂ CH₂ Cl or CH₂ CH═CH₂ ;

R₁₆ is C₁ -C₂ alkyl;

R₁₇ is C₁ -C₂ alkyl;

R₁₈ is C₁ -C₃ alkyl or N(CH₃)₂ ;

R₁₉ is C₁ -C₃ alkyl or CH₂ CH═CH₂ ;

m is 0 or 1;

n is 0 or 2;

Q₁ is O, S or SO₂ ;

Q₂ is O or S; and

W is O, S or SO₂ ;

A is ##STR7## X is CH₃, OCH₃, OC₂ H₅, F, Cl, Br, CF₃ or OCHF₂ ;

T is H, SeCH₃, SeC₆ H₅, SCH₃ or ##STR8## Y is SeCH₃, SeC₆ H₅, ##STR9##OSi(CH₃)₃, CH₂ OH or CH₂ OSi(CH₃)₃ ; Z is CH or N;

X₁ is CH₃, OCH₃ or OC₂ H₅ ;

E is F, Cl or Br;

G is CH(OCH₃)₂, CH(OC₂ H₅)₂, ##STR10## or C₆ H₅ ; R₂₀ is H, CH₃, CF₃,OCH₃, F, Cl, Br or NO₂ ;

p is 0, 1 or 2; and

q is 0, 1 or 2;

provided that

(1) when X is F, Cl or Br, then Z is CH;

(2) when m is 1, then R₉ is H;

(3) the sum of p and q is less than or equal to 2;

(4) when A is A-2 and L is L-1, then R₁ is C₂ -C₄ alkyl, C₂ -C₄ alkoxy,OCH₂ CH₂ OCH₃, CO₂ R₁₅, SO₂ NR₁₆ R₁₇, SO₂ N(OCH₃)CH₃, OSO₂ R₁₈, WCF₃,WCHF₂, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₁ -C₂ alkyl substitutedwith OCH₃ or OCH₂ CH₃, C₆ H₅, ##STR11## (5) when A is A-4, then L isL-1, L-2, L-3, L-4, L-5, L-6, L-7, L-8 or L-9;

(6) when A is A-4 and L is L-1, then R₁ is C₁ -C₄ alkyl, C₁ -C₄ alkoxy,F, Cl, Br, NO₂, CF₃, CO₂ R₁₅, SO₂ NR₁₆ R₁₇, SO₂ N(OCH₃)CH₃, OSO₂ R₁₈,S(O)_(n) C₁ -C₃ alkyl, C₁ -C₂ alkyl substituted with OCH₃ or OCH₂ CH₃,C₆ H₅, ##STR12## (7) when A is A-5 and L is L-1, then R₁ is C₂ -C₄alkyl, C₂ -C₄ alkoxy, SO₂ NR₁₆ R₁₇, SO₂ N(OCH₃)CH₃, C₆ H₅, ##STR13## (8)when A is A-5, L is L-1 and R₁ is SO₂ NR₁₆ R₁₇ or SO₂ N(OCH₃)CH₃, then Eis F or Br;

(9) when A is A-5 and L is L-4, L-5 or L-6, then R₅ is C₁ -C₃ alkyl, F,Cl, Br, NO₂, SO₂ NR₁₆ R₁₇, SO₂ N(OCH₃)CH₃ or S(O)_(n) R₁₉ ;

(10) when A is A-5 and L is L-10, L-11, L-12, L-13, L-14, L-15, L-16 orL-17, then E is Cl or Br;

(11) when A is A-5, then L is other than L-8, L-11 or L-17; and

(12) R₁₃ and R₁₄ are not simultaneously H; and their agriculturallysuitable salts.

Preferred for reasons of their higher herbicidal acivity, greater plantgrowth regulant activity and/or more favorable ease of synthesis are:

(1) Compounds of Formula I where R is H and A is A-1;

(2) Compounds of Preferred 1 where R₂ is H, R₂₀ is H, X is CH₃ or OCH₃,T is H, p is 0 and q is 0;

(3) Compounds of Preferred 2 where L is L-1, L-5, L-8, L-10, L-11, L-15or L-17;

(4) Compounds of Preferred 3 where L is L-1 and R₁ is C₁ -C₂ alkyl, C₁-C₂ alkoxy, Cl, NO₂, CO₂ CH₃, CO₂ C₂ H₅, SO₂ N(CH₃)₂, SO₂ CH₃, OSO₂ CH₃or WCHF₂.

Specifically preferred for reasons of their highest herbicidal activity,greatest plant growth regulant activity and/or most favorable ease ofsynthesis are:

2-[[[4-methoxy-6-(phenoxymethyl)pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoicacid, methyl ester, m.p. 178°-180° C.;

2-[[[bis(4,6-trifluoromethyl]pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoicacid, methyl ester, m.p. 153°-161° C.;

2-[[[4-methoxy-6-(methylselenylmethyl)pyrimidin-2-yl]aminocarbonyl[aminosulfonyl]benzoicacid, methyl ester, m.p. 126°-130° C.; and

2-[[[4-methoxy-6-(phenylthiomethyl)pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoicacid, methyl ester, m.p. 149°-152° C.

DETAILED DESCRIPTION OF THE INVENTION Synthesis

The compounds of Formula I can be prepared by reacting an appropriatesulfonyl isocyanate II with the appropriately substitutedaminoheterocycle III, as shown in Equation 1. R, A and L are aspreviously defined. ##STR14##

The reaction is best performed in an inert solvent such as methylenechloride or toluene at 25° to 100° C., for 1 to 24 hours. Isolation ofthe product can be achieved by concentrating the solution andtrituration with an appropriate solvent such as butyl chloride.

Alternatively, compounds of Formula I may be prepared by reacting thesulfonamides of Formula IV with the carbamates of Formula V (R'=CH₃) inthe presence of an excess of trimethylaluminum, as shown in Equation 2,where L, R and A are as previously defined, provided R₁ is other thanCO₂ R₁₅. ##STR15##

The reactions are best performed in an inert solvent such as methylenechloride at the reflux point of the solution (40° C.) for 10 to 24hours. Isolation of the product is best achieved by exposing thereaction mixture to acetic acid, separation of the layers andconcentrating the organic layer to a solid.

Alternatively, compounds of Formula I can be prepared by exposing aphenyl carbamate V (R'=Ph) to the sulfonamide IV in an appropriatesolvent such as dioxane at 25° to 100° C. in the presence of a strongbase such as 1,8-diazabicyclo[5.4.0]undec-7-ene; acid workup affords thedesired product. See EPO Publication No. 44,807 for details. Therequired carbamates can be prepared from the corresponding amines IIIand dimethyl or diphenyl carbonate or methyl or phenyl chloroformate anda base such as sodium hydride.

The sulfonyl isocyantes II used in the preparation of I are known in theart and can be prepared by known methods. For example, isocyanates canbe prepared by exposing an appropriate benzene or heterocyclicsulfonamide to phosgene in the presence of an alkyl isocyanate and anamine catalyst such as 1,4-diazabicyclo[2.2.2]octane at the reflux pointof the solvent. See H. Ulrich and A. A. Y. Sayigh, Newer Methods ofPreparative Organic Chemistry, Vol. VI, p. 223-241, Academic Press, NewYork and London, W. Forest Ed.

The sulfonamides IV used in the preparation of I are also known in theart and can be prepared by known methods. For example, exposure of asulfonyl chloride to ammonium hydroxide results in the formation of thecorresponding sulfonamides, e.g., Crossley et al., J. Am. Chem. Soc.,60, 2223 (1938). The appropriate sulfonyl chlorides are prepared byseveral methods. For example, treatment of a substituted aromatic orheterocyclic ring with chlorosulfonic acid in carbon tetrachlorideresults in the formaton of the sulfonyl chloride. See Clark et al., Org.Synth. Coll., Vol. 1 2nd Ed. 1941, p. 85.

An alternative method of preparation of sulfonyl chlorides can beachieved from an appropriate amine. Diazotization of an amine withsodium nitrite in acid, followed by exposure of the resulting diazoniumsalt to sulfur dioxide in the presence of cuprous chloride results inthe formation of a sulfonyl chloride. See H. L. Yale and F. Sowinski, J.Org. Chem., 25, 1824, (1960).

The heterocyclic amines III where A is A-1 (T=H) or A-5 may be preparedvia generation of the lithium anion of VI, followed by addition of theappropriate electrophile, as shown in Equation 3, where E, R, X, Y and Zare as previously defined. R" is H, CH₃, --C(CH₃)₂, --CO₂ CH₃ or --CO₂Ph. ##STR16##

The reaction is generally carried out by adding the heterocycle (VI) toa solution of lithium diisopropylamide (LDA) in tetrahydrofuran at -78°C. followed by the addition of the electrophile (E⁺ or Y⁺, for example,N-bromosuccinimide or dimethyldiselenide). In the case where R"=CO₂ CH₃or CO₂ Ph, removal of this group is accomplished by treatment with anaqueous base such as potassium hydroxide in methanol.

A second group, T, may be introduced in several ways. Treatment of thereaction mixture with an excess of LDA followed by sequential additionof electrophiles, Y⁺ and T⁺, affords the desired dialkylated compound(IIIb) as shown in Equation 4. ##STR17##

Alternatively, the product of addition of Y⁺ may be isolated and thenretreated as described previously with LDA and T⁺ to afford thedisubstituted compound (IIIb).

Compounds of Formulas IIIa or IIIb wherein Y is OSi(CH₃)₃ or CH₂OSi(CH₃)₃ can be prepared via silylation of the corresponding alcohols.

Reference to the following papers is suggested for further informationregarding the preparation of lithiated heterocycles: T. Murray, J. Hay,D. Portlock, J. Wolfe, J. Org. Chem., 39, 595 (1974), J. Stowell,Carbanions in Organic Synthesis, John Wiley and Sons, New York,Chichester, Brisbane, Toronto, Singapore, (1979).

The heterocyclic amines III where A is A-2 are prepared via the sequencedescribed below in Equation 5. R, R" and X₁ are as defined previously.Oxidation of the thioether or selenide and thermal elimination of theresulting sulfoxide or selenoxide affords the target compound IIIc. Fora review on thermal elimination of sulfoxides and selenoxides, see. D.J. Clive, Tetrahedron, 34, 1940 (1978), H. Reich, Acc. Chem. Res., 12,22 (1979), B. M. Trost. T. H. Saltzman, K. Hiroi, J. Am. Chem. Soc., 98,4887 (1976). ##STR18##

The prerequisite starting heterocycles VI and VIa used in thepreparation of A-1, A-2 and A-5 are generally known in the art and arereviewed in The Chemistry of Heterocyclic Compounds, Interscience Publ.,New York and London. See D. J. Brown, "The Pyrimidines", Vol. XVI and E.M. Smolin and L. Rapaport, "s-Triazines and Derivatives", Vol. XIII. Foradditional references, see F. C. Schaefer, U.S. Pat. No. 3,154,547 andK. R. Huffman and F. C. Schaefer; J. Org. Chem., 28, 184 (1963).

The heterocyclic amines III where R is a methyl group may be preparedfrom the corresponding compounds where R is hydrogen by known methods.An example of this type of transformation is described in: J. Chem. Soc.Perkin I, 1569 (1981).

The heterocyclic amines III, where A is A-3 and A-4 are best prepared bythe exposure of 1,1,1,5,5,5-hexafluoroacetylacetone to guanidinecarbonate in an inert solvent such as DMSO as outlined in Equation 6.##STR19##

The reaction is best performed at 25° to 125° C. for 1 to 24 hours. Theproduct is usually isolated by pouring the reaction mixture over ice andcollecting the resulting solids.

Many of the heterocyclic amines of Formula III in which A is A-1, T isH, Y is as defined previously and q=0 may be prepared by methods knownin the art or as described in European Patent Office Publication No.84,224, published July 27, 1983. For example, when Y is a phenoxysubstituent, the known acetoacetic ester VII (U.S. Pat. No. 3,775,467)can be condensed with guanidine carbonate in a suitable solvent such asethanol preferably above ambient temperature to yield the pyrimidineintermediate VIII, as shown in Equation 7. This can be converted to thechloropyrimidine IX upon treatment with excess phosphorous oxychloride,preferably with heating above ambient temperature. Reaction of IX withan appropriate alkali metal alkoxide in alcohol solvent affords thecorresponding alkoxy-substituted pyrimidine of Formula IIIf. ##STR20##wherein R'=CH₃ or C₂ H₅ ; and

M=alkali metal.

The synthesis of heterocyclic amines of Formula III wherein A is A-6 canbe accomplished as depicted in Equation 8. An alkali metal salt of theappropriate 4-hydroxypyrimidine or triazine X is prepared from X and asuitable base such as an alkali metal alkoxide, for example potassiumt-butoxide, in a polar aprotic solvent such as dimethylformamide (DMF).This salt (XI) is then treated with the appropriate haloacetaldehydeacetal such as 2-bromomethyl-1,3-dioxolane and heated in the range of50° to 150° C., preferably at 110° to 130° C., for 1 to 24 hours. Thedesired products are conveniently isolated by chromatography on silicagel to separate them from the unwanted N-alkylated isomers. ##STR21##wherein R, X₁, Z and G are as defined previously;

M is an alkali metal;

R' is lower alkyl; and

X² is halogen.

Agriculturally suitable salts of compounds of Formula I are also usefulherbicides and can be prepared in a number of ways known to the art. Forexample, metal salts can be made by contacting compounds of Formula Iwith a solution of an alkali or alkaline earth metal salt having asufficiently basic anion (e.g., hydroxide, alkoxide, carbonate orhydroxide). Quaternary amine salts can be made by similar techniques.

Salts of compounds of Formula I can also be prepared by exchange of onecation for another. Cationic exchange can be effected by direct contactof an aqueous solution of a salt of a compound of Formula I (e.g.,alkali or quaternary amine salt) with a solution containing the cationto be exchanged. This method is most effective when the desired saltcontaining the exchanged cation is insoluble in water and can beseparated by filtration.

Exchange may also be effected by passing an aqueous solution of a saltof a compound of Formula I (e.g., an alkali metal or quaternary aminesalt) through a column packed with a cation exchange resin containingthe cation to be exchanged for that of the original salt and the desiredproduct is eluted from the column. This method is particularly usefulwhen the desired salt is water-soluble.

Acid addition salts, useful in this invention, can be obtained byreacting a compound of Formula I with a suitable acid, e.g.,p-toluenesulfonic acid, trichloroacetic acid or the like.

The following examples teach the synthesis of some of the compoundscontained within this invention in greater detail.

EXAMPLE 1 Methyl(4-fluoromethyl-6-methoxypyrimidin-2-yl)carbamate

To a stirred solution of lithium diisopropylamide (8.3 mmol) intetrahydrofuran at -78° C. was added(4-methyl-6-methoxypyrimidin-2-yl)carbamic acid, methyl ester (4.16mmol). The solution was stirred at -78° C., thenN-fluoro-N-2,2-dimethylpropyl-p-toluenesulfonamide (4.6 mmol) in THF wasadded dropwise. The solution was stirred an additional 1 hour thenquenched with brine. A crystalline product was collected, 0.71 g, m.p.98°-102° C. NMR (90 MHz, CDCl₃): δ 4.0 (s, 3H); 4.1 (s, 3H); 5.5 (d,2H); 1.8 (s, 1H); 8.2 (s, 1H).

EXAMPLE 2 4-Methoxy-6-(phenoxymethyl)-2-pyrimidinamine

A mixture of 7.8 g (36 mmol) of ethyl 2-oxo-4-phenoxybutanoate and 3.4 g(38 mmol) guanidine carbonate was heated to reflux in 100 ml abs.ethanol for 48 hours. Filtration of the cooled suspension afforded 4.6 gof 2-amino-4-hydroxy-6-phenoxymethylpyrimidine in two crops, m.p.253°-254° (dec). This intermediate (4.3 g, 20 mmol) was heated to refluxin 50 ml phosphorous oxychloride for 2 hours then evaporated. Theresidue was treated with ice-water and neutralized with 10% sodiumhydroxide solution then extracted with chloroform. Evaporation of theextracts left a residue which was purified by dissolution in 15% ethylacetate/methylene chloride and filtration through silica gel. Thefiltrate was concentrated and crystallized fromether/1-chlorobutane/hexanes to yield 0.65 g of2-amino-4-chloro-6-phenoxymethylpyrimidine, m.p. 123°-124°. Anadditional 0.8 g was deposited from the original aqueous phase, m.p.118°-121°, for a total of 1.4 g of product. A 1.0 g (4.2 mmol) portionof this material was reacted with 20 mmol sodium methoxide in 30 mlmethanol at reflux for 2 hours, then concentrated in vacuo. The residuewas triturated with water, collected, water rinsed and dried to 0.9 g ofthe title compound, m.p. 94°-96°. NMR (90 MHz, CDCl₃): δ 3.83 (s, 3H);4.90 (s, 2H); 6.31 (s, 1H); 6.9-7.1 (m, 3H); 7.22-7.45 (m, 2H) ppm.

EXAMPLE 3 4-Ethylidene-6-methoxy-2-pyrimidinamine

To a stirring solution of4-methoxy-6-[1-(phenylselenyl)ethyl]-2-pyrimidinamine (14.3 mmol) in 100ml of CH₂ Cl₂ cooled to -78° C. was added in one portionm-chloroperbenzoic acid (14.3 mmol). The solution was warmed to roomtemperature, diluted with ether and filtered. A white crystalline solid(0.17 g), m.p. 119°-122° C. was isolated. NMR (200 MHz, CDCl₃) δ 3.87(s, 3H); 5.9 (br s, 2H); 5.5 (d, d, 1H); 6.0 (s, 1H); 6.2-6.6 (m, 2H).

EXAMPLE 4 4-Methoxy-6-phenylselenylmethyl-2-pyrimidinamine

To a stirring solution of lithium diisopropylamide (203 mmol) intetrahydrofuran, cooled to -78° C. was addedmethyl(4-methyl-6-methoxypyrimidin-2-yl)carbamate (50.7 mmol). Afterstirring one hour at -78° C. phenyl diselenide (50.7 mmol) was added,stirred an additional 30 minutes, followed by the addition of methyliodide (50.7 mmol). The reaction mixture was warmed to -30° C., quenchedwith brine, the organic phase separated, dried and concentrated. Theresulting oil was filtered through a column of silica gel to give 13.3 gof an oil. The crude oil (12.2 g) was dissolved in 206 ml of methanoland 9.4 ml of water, potassium hydroxide (105 mmol) was added and thesolution was refluxed for 3 hours. The reaction mixture was cooled to 0°C., neutralized to pH 7 with concentrated HCl and extracted with ethylacetate. The crude product was flash chromatographed with ether/hexane(35:65) to yield 3 products. Product 1 (0.24 g), the title compound, wasobtained as a solid with m.p. 115°-117° C., NMR (60 MHz, CDCl₃): δ 3.9(s, 2H); 4.0 (s, 3H); 5.2 (br. s, 2H); 6.0 (s, 1H); 7.2-7.5 (m, 5H).Product 2 (1.3 g), 4-methoxy-6-[1-methyl-1-(phenylselenyl)ethyl]-2-pyrimidinamine, m.p. 104°-106° C., was the dimethylated product. NMR(200 MHz, CDCl₃): δ 1.7 (s, 6H); 3.9 (s, 3H); 5.2 (br. s, 2H); 6.8 (s,1H); 7.3 (m, 5H). Product 3 (4.6 g) was the mono methylatedaminopyrimidine of Formula III in which A is A-1 (X=OCH₃, Y=SePh, T=CH₃,Z=CH, R=H).

EXAMPLE 5 Methyl[4-methoxy-6-(phenylthiomethyl)pyrimidin-2-yl]carbamate

To a stirring solution of lithium diisopropylamide (126.9 mmol) in 400ml of tetrahydrofuran at -78° C. was addedmethyl(4-methyl-6-methoxypyrimidin-2-yl)carbamate (50.8 mmol). Afterstirring one hour at -78° C., phenyl disulfide (127 mmol) was added.Work-up with brine afforded 30 g of a crude oil. Flash chromatography ofthe crude product with ether/hexane (50:50) gave two products. Product 1(5.6 g) a clear oil, was the desired product (A-1, X=OCH₃, Y=H, Z=CH,T=SPh), NMR (60 MHz, CDCl₃): δ 3.9 (s, 3H); 4.0 (s, 3H); 4.2 (s, 2H);6.5 (s, 1H); 7.3 (m, 5H); 8.2 (br. s, 1H). Product 2 (1.2 g) was thedithiolated carbamate of Formula V in which R' is CH₃, R is H, and A isA-1 (X=OCH₃, Y=SPh, Z=CH, T=SPh). NMR (60 MHz, CDCl₃): δ 3.7 (s, 3H);3.9 (s, 3H); 5.4 (s, 1H); 6.4 (s, 1H); 7.0-7.5 (m, 10H); 8.4 (br. s,1H).

EXAMPLE 6 4-Methoxy-6-(methylselenylmethyl)-2-pyrimidinamine

To a stirring solution of potassium hydroxide (15.6 mmol) in H₂ O (77.5mmol) and 50 ml of methanol was addedmethyl[4-methoxy-6-(methylselenylmethyl)pyrimidin-2-yl]carbamate (5.2mmol). The solution was heated to the reflux point for 3 hours, thencooled to 0° C. The solution was neutralized to pH7 with concentratedHCl and then the solvent was removed under reduced pressure. Theresulting residue was washed with THF to afford 1.3 g, m.p. 88°-91° C.;NMR (200 MHz, CDCl₃): δ 2.01 (s, 3H); 3.48 (s, 2H); 3.85 (s, 3H); 5.1(br. s, 2H); 5.99 (s, 1H).

EXAMPLE 7 4,6-Bis(trifluoromethyl)-2-pyrimidinamine

A mixture of guanidine carbonate (180 mmol) and1,1,1,5,5,5-hexafluoro-2,4-pentanedione (120 mmol) was dissolved in 60ml of DMSO and warmed to 110° C. for 2 to 3 hours. Flash chromatographyof the crude reaction product with ether/hexane (50:50) afforded 13.8 gof the title compound as a white crystalline solid, m.p. 94.5°-96° C.NMR (60 MHz, CDCl₃): δ 6.5 (br. s, 2H); 7.2 (s, 1H). A second productisolated was the hydroxypyrimidine (A is A-3): m.p. 116°-118.5° C. NMR(90 MHz, CDCl₃): δ 7.1 (br. s, 3H); 7.3 (s, 1H).

EXAMPLE 8 Methyl2-[[[(4-methoxy-6-(phenylselenylmethyl)pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoate

To a stirring solution of4-methoxy-6-(phenylselenylmethyl)-2-pyrimidinamine (0.67 mmol) in 25 mlof methylene chloride was added o-carbomethoxybenzenesulfonyl isocyanate(0.84 mmol). The solution was stirred for 16 hours at room temperatureand concentrated. The resulting solid was washed with butyl chloride toafford 0.25 g of the desired product, m.p. 134°-139° C. NMR (200 MHz,CDCl₃): δ 3.90 (s, 3H); 3.95 (s, 3H); 4.1 (s, 2H); 6.1 (s, 1H); 7.3 (m,3H); 1.5 (m, 3H); 7.7 (m, 3H); 8.3 (m, 1H); 12.8 (br. s, 1H).

EXAMPLE 9 Methyl2-[[[4-(fluoromethyl)-6-methylpyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoate

To a stirring solution of 4-methyl-6-fluoromethyl-2-pyrimidinamine (1.4mmol) in 25 ml of CH₂ Cl₂ was added o-carbomethoxybenzenesulfonylisocyanate (1.77 mmol). After stirring 16 hours the reaction wasconcentrated and the resulting solid washed with butyl chloride toafford 0.28 g of the desired product, m.p. 181°-186° C. NMR (90 MHz,CDCl₃): δ 2.5 (s, 3H); 4.0 (s, 3H); 5.2 (s, 1H); 5.7 (s, 1H); 7.0 (s,1H); 7.6 (m, 3H); 8.2 (m, 1H); 10.3 (s, 1H); 12.8 (br. s, 1H).

EXAMPLE 10 Methyl2-[[[bis(4,6-trifluoromethyl)pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoate

To a stirring solution of 4,6-bis(trifluoromethyl)-2-pyrimidinamine(2.16 mmol) in 25 ml of methylene chloride was addedo-carbomethoxybenzenesulfonyl isocyanate (2.38 mmol). After stirring 10hours at room temperature the reaction was concentrated and theresulting solid was washed with butyl chloride to afford 0.36 g of thetitle compound, m.p. 153°-161° C. NMR (90 MHz, CDCl₃): δ 4.0 (s, 3H);7.5-7.8 (m, 4H); 8.3-8.4 (m, 1H); 11.0-11.6 (br. s, 2H).

EXAMPLE 11 Methyl2-[[[4-Methoxy-6-(phenoxymethyl)pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoate

To a mixture of 0.23 g (1.0 mmol) of4-methoxy-6-(phenoxymethyl)-2-pyrimidinamine in 15 ml dry acetonitrilewas added 0.48 g (2.0 mmol) o-carbomethoxybenzenesulfonyl isocyanate andstirred at ambient temperature overnight. Ether was added to thesuspension of white solids which were then collected by filtration toafford 0.37 g of the title compound, m.p. 178°-180°. NMR (90 MHz, CDCl₃+DMSO-d₆): δ 3.91 (s, 3H); 4.02 (s, 3H); 5.20 (s, 2H); 6.69 (s, 1H);7.0-7.9 (m, 8H); 8.5 (m, 1H); 9.20 (s, NH); 12.9 (s, NH) ppm; IR (nujol)1725, 1700 cm⁻¹.

EXAMPLE 12 4-(1,3-Dioxolan-2-ylmethoxy)-6-methoxy-2-pyrimidinamine

A solution of 8.5 g (0.060 mol) 2-amino-6-methyl-4-pyrimidinone in 45 mLanhydrous dimethylformamide (DMF) was treated with 6.7 g (0.060 mol)potassium t-butoxide then stirred for 10 minutes at ambient temperature.Subsequently, 7.6 mL (0.073 mol) of 2-bromomethyl-1,3-dioxolane wasadded and the mixture heated to 120° for 3 hours. The DMF was thenevaporated under reduced pressure and the residue partitioned betweenwater and ethyl acetate. The aqueous phase was extracted with twoadditional portions of ethyl acetate then the combined organic phase waswashed with water, brine, then dried (MgSO₄) and evaporated to an oil.Chromatography on silica gel with 10% ethyl acetate/CH₂ Cl₂ as theeluant afforded 2.3 g of the title compound as a viscous oil. NMR(CDCl₃): δ 3.9 (s, 3H), 4.0 (m, 4H), 4.3 (d, J=4 Hz, 2H), 5.15 (NH, br),5.27 (t, J=4 Hz, 1H), 5.55 (s, 1H) ppm.

EXAMPLE 13 Methyl2-[[[4-(1,3-Dioxolan-2-ylmethoxy)-6-methoxypyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoate

A solution of the aminopyrimidine of the preceding example (0.5 g, 2.2mmol) was dissolved in 10 mL dry acetonitrile then treated with 0.6 g(2.4 mmol) of 2-carbomethoxybenzenesulfonyl isocyanate. The mixture waswarmed briefly then stirred at ambient temperature for several hours andsubsequently evaporated to dryness. Trituration of the residue withether afforded 0.85 g of the title compound as colorless crystals, m.p.102°-104° (dec.). NMR (200 MHz, CDCl₃): δ 3.90 (s, 3H), 4.05 (s, 3H),3.95 (m, 4H), 4.39 (d, J=4 Hz, 2H), 5.26 (t, J=4 Hz, 1H), 5.85 (s, 1H),7.2 (NH, br), 7.68 (m, 3H), 8.45 (m, 1H), 12.4 (NH, br) ppm; IR (nujol)1715, 1730 cm⁻¹.

Using the procedures of Examples 1-13 the following compounds may beprepared.

                                      TABLE 1a                                    __________________________________________________________________________     ##STR22##                                                                    R.sub.1    R.sub.2                                                                            R  X     T   Y         Z  m.p. (°C.)                   __________________________________________________________________________    H          H    H  OCH.sub.3                                                                           H   SPh       CH                                     H          H    H  OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   SO.sub.2 Ph                                                                             CH                                     CO.sub. 2 CH.sub.3                                                                       H    H  CH.sub.3                                                                            H   OPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SeCH.sub.3                                                                        SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SeCH.sub.3                                                                        SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SeCH.sub.3                                                                        SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SeCH.sub.3                                                                        SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SePh                                                                              SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SePh                                                                              SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SePh                                                                              Sph       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SePh                                                                              SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SePh                                                                              SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         OPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H                                                                                  ##STR23##                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H                                                                                  ##STR24##                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H                                                                                  ##STR25##                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         CH.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         CH.sub.3                                                                            H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         CH.sub.3                                                                            H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         CH.sub.3                                                                            H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         CH.sub.3                                                                            SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         CH.sub.3                                                                            SPh SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         CH.sub.3                                                                            H   OPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  CH.sub.3                                                                            H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  CH.sub. 3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  CH.sub.3                                                                            H   SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  CH.sub.3                                                                            H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  CH.sub.3                                                                            H   OPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  CH.sub.3                                                                            SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  CH.sub.3                                                                            SeCH.sub.3                                                                        SePh      CH                                     CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  CH.sub.3                                                                            SeCH.sub.3                                                                        SPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  CH.sub.3                                                                            SeCH.sub.3                                                                        SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        3-CF.sub.3                                                                         H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  CH.sub.3                                                                            H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        6-CF.sub.3                                                                         H  CH.sub.3                                                                            H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        6-CF.sub.3                                                                         H  CH.sub.3                                                                            H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  CH.sub.3                                                                            H   OPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  CH.sub.3                                                                            SPh SPh       CH                                     CO.sub.2 CH.sub.3                                                                        3-Cl H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        5-Cl H  CH.sub.3                                                                            H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        6-Cl H  CH.sub.3                                                                            H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        6-Cl H  CH.sub.3                                                                            H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        5-Br H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        5-Br H  CH.sub.3                                                                            H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        6-Br H  CH.sub.3                                                                            H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        3-F  H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        3-F  H  CH.sub.3                                                                            H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        3-F  H  CH.sub.3                                                                            H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-F  H  CH.sub.3                                                                            H   SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        6-F  H  CH.sub.3                                                                            H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        6-F  H  CH.sub.3                                                                            SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        3-F  H  CH.sub.3                                                                            SePh                                                                              SePh      CH                                     CO.sub.2 CH.sub.3                                                                        5-F  H  CH.sub.3                                                                            SPh SPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-CH.sub.3                                                                         H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        6-CH.sub.3                                                                         H  CH.sub.3                                                                            H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH 144-147                             CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SePh      CH 134-139                             CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SPh       CH 149-152                             CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SOPh      CH 176-178.5                           CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   OPh       CH 178-180                             CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SPh SPh       CH 125-127                             CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         OPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H                                                                                  ##STR26##                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H                                                                                  ##STR27##                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H                                                                                  ##STR28##                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           SPh SPh       CH                                     CO.sub.2 CH.sub. 3                                                                       H    CH.sub.3                                                                         OCH.sub.3                                                                           H   OPh       CH                                     CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   OPh       CH                                     CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SePh      CH                                     CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SPh       CH                                     CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        3-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        3-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   OPh       CH                                     CO.sub.2 CH.sub.3                                                                        6-CF.sub.3                                                                         H  OCH.sub.3                                                                           SPh SPh       CH                                     CO.sub.2 CH.sub.3                                                                        3-Cl H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        3-Cl H  OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        3-Cl H  OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-Cl H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        5-Br H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        5-Br H  OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        5-Br H  OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        6-F  H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        3-F  H  OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        5-F  H  OCH.sub.3                                                                           H   SOPh      CH                                     CO.sub.2 CH.sub.3                                                                        6-F  H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.3                                                                        3-F  H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        5-F  H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     CO.sub.2 CH.sub.3                                                                        6-F  H  OCH.sub.3                                                                           SPh SPh       CH                                     CO.sub.2 CH.sub.3                                                                        3-CH.sub.3                                                                         H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.3                                                                        5-CH.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   SePh      N                                      CO.sub.2 CH.sub.3                                                                        H    H  Cl    H   OPh       CH 195-197                             CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SPh       N                                      CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   SOPh      N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   OPh       N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SeCH.sub.3                                                                        SePh      N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SPh       N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SOPh      N                                      CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SeCH.sub.3                                                                        SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SePh                                                                              SePh      N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SPh       N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SOPh      N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SePh      N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SPh       N                                      CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SOPh      N                                      CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         OPh       N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H                                                                                  ##STR29##                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H                                                                                  ##STR30##                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H                                                                                  ##STR31##                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SePh      N                                      CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       N                                      CO.sub. 2 CH.sub.3                                                                       H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           SPh SPh       N                                      CO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   OPh       N                                      CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SePh      N                                      CO.sub.2 CH.sub.3                                                                        3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       N                                      CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SOPh      N                                      CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   OPh       N                                      CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SePh      N                                      CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SPh       N                                      CO.sub.2 CH.sub.3                                                                        6-OCH.sub.3                                                                        H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        3-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        3-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SePh      N                                      CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       N                                      CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   OPh       N                                      CO.sub.2 CH.sub.3                                                                        6-CF.sub.3                                                                         H  OCH.sub.3                                                                           SPh SPh       N                                      CO.sub.2 CH.sub.3                                                                        3-Cl H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        3-Cl H  CH.sub.3                                                                            H   SePh      N                                      CO.sub.2 CH.sub.3                                                                        3-Cl H  OCH.sub.3                                                                           H   SPh       N                                      CO.sub.2 CH.sub.3                                                                        5-Cl H  CH.sub.3                                                                            H   SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        5-Br H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        5-Br H  CH.sub.3                                                                            H   SePh      N                                      CO.sub.2 CH.sub.3                                                                        5-Br H  OCH.sub.3                                                                           H   SPh       N                                      CO.sub.2 CH.sub.3                                                                        6-F  H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        6-F  H  OCH.sub.3                                                                           H   SePh      N                                      CO.sub.2 CH.sub.3                                                                        3-F  H  CH.sub.3                                                                            H   SPh       N                                      CO.sub.2 CH.sub.3                                                                        5-F  H  OCH.sub.3                                                                           H   SOPh      N                                      CO.sub.2 CH.sub.3                                                                        6-F  H  CH.sub.3                                                                            H   SO.sub.2 Ph                                                                             N                                      CO.sub.2 CH.sub.3                                                                        3-F  H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        5-F  H  CH.sub.3                                                                            SePh                                                                              SePh      N                                      CO.sub.2 CH.sub.3                                                                        6-F  H  OCH.sub.3                                                                           SPh SPh       N                                      CO.sub.2 CH.sub.3                                                                        3-CH.sub.3                                                                         H  CH.sub.3                                                                            H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.3                                                                        5-CH.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       N                                      Cl         H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH 134-140                             Cl         H    H  OCH.sub.3                                                                           H   SPh       CH 184-186                             Cl         H    H  CH.sub.3                                                                            H   SePh      CH                                     Cl         H    H  OCH.sub.3                                                                           H   SOPh      CH 148-152                             Cl         H    H  CH.sub.3                                                                            SPh SPh       CH                                     Cl         H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     Cl         H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     Cl         H    H  Br    H   SePh      CH                                     Cl         H    H  OCH.sub.3                                                                           H   OPh       CH 196-198                             Cl         H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     Cl         H    H  OCH.sub.3                                                                           H   SPh       N                                      Cl         H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     Cl         H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     Cl         H    H  OCH.sub.3                                                                           SPh SPh       N                                      Cl         H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      Cl         H    H  F     H   SPh       CH                                     Cl         H    H  OCH.sub.3                                                                           SPh SPh       CH 174-175.5                           Cl         H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     Cl         H    H  CF.sub.3                                                                            H   SPh       CH                                     Cl         H    H  OCH.sub.3                                                                           H   OPh       N                                      Cl         H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      Cl         H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     Cl         H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     Cl         5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     Cl         5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     Cl         3-F  H  OCH.sub.3                                                                           H   SePh      CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           H   SPh       CH 166-168                             SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  CH.sub.3                                                                            H   SePh      CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  CH.sub.3                                                                            SPh SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  Br    H   SePh      CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           H   OPh       CH 222-224                             SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           H   SPh       N                                      SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           SPh SPh       N                                      SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  F     H   SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           SPh SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  CF.sub.3                                                                            H   SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           H   OPh       N                                      SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SO.sub. 2 N(CH.sub.3).sub.2                                                              H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                               3-F  H  OCH.sub.3                                                                           H   SePh      CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           H   SPh       CH                                     NO.sub.2   H    H  CH.sub.3                                                                            H   SePh      CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     NO.sub.2   H    H  CH.sub.3                                                                            SPh SPh       CH                                     NO.sub.2   H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     NO.sub.2   H    H  Br    H   SePh      CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           H   OPh       CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           H   SPh       N                                      NO.sub.2   H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           SPh SPh       N                                      NO.sub.2   H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      NO.sub.2   H    H  F     H   SPh       CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           SPh SPh       CH                                     NO.sub.2   H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     NO.sub.2   H    H  CF.sub.3                                                                            H   SPh       CH                                     NO.sub.2   H    H  OCH.sub.3                                                                           H   OPh       N                                      NO.sub.2   H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      NO.sub.2   H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     NO.sub.2   H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     NO.sub.2   5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     NO.sub.2   5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     NO.sub.2   3-F  H  OCH.sub.3                                                                           H   SePh      CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   SePh      CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     SO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SPh SPh       CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     SO.sub.2 CH.sub.3                                                                        H    H  Br    H   SePh      CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   OPh       CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   SPh       N                                      SO.sub.2 CH.sub.3                                                                        H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SPh SPh       N                                      SO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      SO.sub.2 CH.sub.3                                                                        H    H  F     H   SPh       CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           SPh SPh       CH                                     SO.sub.2 CH.sub.3                                                                        H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     SO.sub.2 CH.sub.3                                                                        H    H  CF.sub.3                                                                            H   SPh       CH                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   OPh       N                                      SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SO.sub.2 CH.sub.3                                                                        H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 CH.sub.3                                                                        5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 CH.sub.3                                                                        3-F  H  OCH.sub.3                                                                           H   SePh      CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           H   SPh       CH                                     CF.sub.3   H    H  CH.sub.3                                                                            H   SePh      CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CF.sub.3   H    H  CH.sub.3                                                                            SPh SPh       CH                                     CF.sub.3   H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     CF.sub.3   H    H  Br    H   SePh      CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           H   OPh       CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           H   SPh       N                                      CF.sub.3   H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           SPh SPh       N                                      CF.sub.3   H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      CF         H    H  F     H   SPh       CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           SPh SPh       CH                                     CF.sub.3   H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CF.sub.3   H    H  CF.sub.3                                                                            H   SPh       CH                                     CF.sub.3   H    H  OCH.sub.3                                                                           H   OPh       N                                      CF.sub.3   H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      CF.sub.3   H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CF.sub.3   H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     CF.sub.3   5-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH -CF.sub.3                                                                     3-CF.sub.3 H OCH.sub.3 H SPh CH                                               1                                   CF.sub.3   6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           H   SPh       CH                                     CH.sub.3   H    H  CH.sub.3                                                                            H   SePh      CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CH.sub.3   H    H  CH.sub.3                                                                            SPh SPh       CH                                     CH.sub.3   H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     CH.sub.3   H    H  Br    H   SePh      CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           H   OPh       CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           H   SPh       N                                      CH.sub.3   H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           SPh SPh       N                                      CH.sub.3   H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      CH.sub.3   H    H  F     H   SPh       CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           SPh SPh       CH                                     CH.sub.3   H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CH.sub.3   H    H  CF.sub.3                                                                            H   SPh       CH                                     CH.sub.3   H    H  OCH.sub.3                                                                           H   OPh       N                                      CH.sub.3   H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      CH.sub.3   H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CH.sub.3   H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     CH.sub.3   3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     CH.sub.3   5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     CH.sub.3   6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CCH                                                                            H    H  CH.sub.3                                                                            H   SePh      CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     OCH.sub.2 CCH                                                                            H    H  CH.sub.3                                                                            SPh SPh       CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     OCH.sub.2 CCH                                                                            H    H  Br    H   SePh      CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           H   OPh       CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           H   SPh       N                                      OCH.sub.2 CCH                                                                            H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     OCH.sub.2 C CH                                                                           H    H  OCH.sub.3                                                                           SPh SPh       N                                      OCH.sub.2 CCH                                                                            H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      OCH.sub.2 CCH                                                                            H    H  F     H   SPh       CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           SPh SPh       CH                                     OCH.sub.2 CCH                                                                            H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     OCH.sub.2 CCH                                                                            H    H  CF.sub.3                                                                            H   SPh       CH                                     OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                           H   OPh       N                                      OCH.sub.2 CCH                                                                            H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      OCH.sub.2 CCH                                                                            H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCH.sub.2 CCH                                                                            H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CCH                                                                            3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CCH                                                                            5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CCH                                                                            6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  CH.sub.3                                                                            H   SePh      CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  CH.sub.3                                                                            SPh SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  Br    H   SePh      CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           H   OPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           H   SPh       N                                      OCH.sub.2CHCH.sub.2                                                                      H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           SPh SPh       N                                      OCH.sub.2CHCH.sub.2                                                                      H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      OCH.sub.2CHCH.sub.2                                                                      H    H  F     H   SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           SPh SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  CF.sub.3                                                                            H   SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.3                                                                           H   OPh       N                                      OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      OCH.sub.2CHCH.sub.2                                                                      H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCH.sub.2CHCH.sub.2                                                                      H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      6-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2CHCH.sub.2                                                                      5-F  H  OCH.sub.3                                                                           H   SePh      CH                                     OCF.sub.3  H    H  OCH.sub. 3                                                                          H   SeCH.sub.3                                                                              CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           H   SPh       CH                                     OCF.sub.3  H    H  CH.sub.3                                                                            H   SePh      CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     OCF.sub.3  H    H  CH.sub.3                                                                            SPh SPh       CH                                     OCF.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     OCF.sub.3  H    H  Br    H   SePh      CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           H   OPh       CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           H   SPh       N                                      OCF.sub.3  H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           SPh SPh       N                                      OCF.sub.3  H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      OCF.sub.3  H    H  F     H   SPh       CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           SPh SPh       CH                                     OCF.sub.3  H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     OCF.sub.3  H    H  CF.sub.3                                                                            H   SPh       CH                                     OCF.sub.3  H    H  OCH.sub.3                                                                           H   OPh       N                                      OCF.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      OCF.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCF.sub.3  H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     OCF.sub.3  3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     OCF.sub.3  6-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     OCF.sub.3  5-F  H  OCH.sub.3                                                                           H   SePh      CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           H   SPh       CH                                     OCHF.sub.2 H    H  CH.sub.3                                                                            H   SePh      CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     OCHF.sub.2 H    H  CH.sub.3                                                                            SPh SPh       CH                                     OCHF.sub.2 H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     OCHF.sub.2 H    H  Br    H   SePh      CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           H   OPh       CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           H   SPh       N                                      OCHF.sub.2 H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           SPh SPh       N                                      OCHF.sub.2 H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      OCHF.sub.2 H    H  F     H   SPh       CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           SPh SPh       CH                                     OCHF.sub.2 H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     OCHF.sub.2 H    H  CF.sub.3                                                                            H   SPh       CH                                     OCHF.sub.2 H    H  OCH.sub.3                                                                           H   OPh       N                                      OCHF.sub.2 H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      OCHF.sub.2 H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCHF.sub.2 H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     OCHF.sub.2 3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     OCHF.sub.2 5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     OCHF.sub.2 6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           H   SPh       CH                                     SCHF.sub.2 H    H  CH.sub.3                                                                            H   SePh      CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     SCHF.sub.2 H    H  CH.sub.3                                                                            SPh SPh       CH                                     SCHF.sub.2 H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     SCHF.sub.2 H    H  Br    H   SePh      CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           H   OPh       CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           H   SPh       N                                      SCHF.sub.2 H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           SPh SPh       N                                      SCHF.sub.2 H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      SCHF.sub.2 H    H  F     H   SPh       CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           SPh SPh       CH                                     SCHF.sub.2 H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     SCHF.sub.2 H    H  CF.sub.3                                                                            H   SPh       CH                                     SCHF.sub.2 H    H  OCH.sub.3                                                                           H   OPh       N                                      SCHF.sub.2 H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      SCHF.sub.2 H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SCHF.sub.2 H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     SCHF.sub.2 3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     SCHF.sub.2 5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     SCHF.sub.2 6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           H   SPh       CH                                     SCH.sub.3  H    H  CH.sub.3                                                                            H   SePh      CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     SCH.sub. 3 H    H  CH.sub.3                                                                            SPh SPh       CH                                     SCH.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     SCH.sub.3  H    H  Br    H   SePh      CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           H   OPh       CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           H   SPh       N                                      SCH.sub.3  H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           SPh SPh       N                                      SCH.sub.3  H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      SCH.sub.3  H    H  F     H   SPh       CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           SPh SPh       CH                                     SCH.sub.3  H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     SCH.sub.3  H    H  CF.sub.3                                                                            H   SPh       CH                                     SCH.sub.3  H    H  OCH.sub.3                                                                           H   OPh       N                                      SCH.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      SCH.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SCH.sub.3  H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     SCH.sub.3  3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     SCH.sub.3  5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     SCH.sub.3  6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           H   SPh       CH 105-109                             CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  CH.sub.3                                                                            H   SePh      CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  CH.sub.3                                                                            SPh SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  Br    H   SePh      CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           H   OPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           H   SPh       N                                      CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.2 CH.sub. 3                                                              H    H  OCH.sub.3                                                                           SPh SPh       N                                      CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  F     H   SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           SPh SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  CF.sub.3                                                                            H   SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           H   OPh       N                                      CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                               6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  CH.sub.3                                                                            H   SePh      CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  CH.sub.3                                                                            SPh SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  Br    H   SePh      CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           H   OPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           H   SPh       N                                      OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           SPh SPh       N                                      OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  F     H   SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           SPh SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  CF.sub.3                                                                            H   SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                           H   OPh       N                                      OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CH.sub.2 OCH.sub.3                                                             6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     Br         H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     Br         H    H  OCH.sub.3                                                                           H   SPh       CH                                     Br         H    H  CH.sub.3                                                                            H   SePh      CH                                     Br         H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     Br         H    H  CH.sub.3                                                                            SPh SPh       CH                                     Br         H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     Br         H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     Br         H    H  Br    H   SePh      CH                                     Br         H    H  OCH.sub.3                                                                           H   OPh       CH                                     Br         H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     Br         H    H  OCH.sub.3                                                                           H   SPh       N                                      Br         H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     Br         H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     Br         H    H  OCH.sub.3                                                                           SPh SPh       N                                      Br         H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      Br         H    H  F     H   SPh       CH                                     Br         H    H  OCH.sub.3                                                                           SPh SPh       CH                                     Br         H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     Br         H    H  CF.sub.3                                                                            H   SPh       CH                                     Br         H    H  OCH.sub.3                                                                           H   OPh       N                                      Br         H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      Br         H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     Br         H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     Br         3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     Br         5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     Br         6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.3  H    H  CH.sub.3                                                                            H   SePh      CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           H   SO.sub. 2 Ph                                                                            CH                                     OCH.sub.3  H    H  CH.sub.3                                                                            SPh SPh       CH                                     OCH.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     OCH.sub.3  H    H  Br    H   SePh      CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           H   OPh       CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           H   SPh       N                                      OCH.sub.3  H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           SPh SPh       N                                      OCH.sub.3  H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      OCH.sub.3  H    H  F     H   SPh       CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           SPh SPh       CH                                     OCH.sub.3  H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     OCH.sub.3  H    H  CF.sub.3                                                                            H   SPh       CH                                     OCH.sub.3  H    H  OCH.sub.3                                                                           H   OPh       N                                      OCH.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      OCH.sub.3  H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     OCH.sub.3  H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.3  3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.3  5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.3  6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           H   SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  CH.sub.3                                                                            H   SePh      CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  CH.sub.3                                                                            SPh SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  Br    H   SePh      CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           H   OPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           H   SPh       N                                      CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           SPh SPh       N                                      CH(OCH.sub.3)CH.sub.3                                                                    H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      CH(OCH.sub.3)CH.sub.3                                                                    H    H  F     H   SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           SPh SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  CF.sub.3                                                                            H   SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.3                                                                           H   OPh       N                                      CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      CH(OCH.sub.3)CH.sub.3                                                                    H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CH(OCH.sub.3)CH.sub.3                                                                    H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     CH(OCH.sub.3)CH.sub.3                                                                    6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  CH.sub.3                                                                            H   SePh      CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  CH.sub. 3                                                                           SPh SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  Br    H   SePh      CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           H   OPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           H   SPh       N                                      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           SPh SPh       N                                      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  F     H   SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           SPh SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  CF.sub.3                                                                            H   SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.3                                                                           H   OPh       N                                      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     C.sub.2 H.sub.5                                                                          H    H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                              CH                                     CH.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           H   SPh       CH                                     CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  CH.sub.3                                                                            H   SePh      CH                                     OCH.sub.2 CH.sub.3                                                                       H    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                             CH                                     OCH.sub.2 CH.sub.2 CH.sub.3                                                              H    H  CH.sub.3                                                                            SPh SPh       CH                                     F          H    H  OCH.sub.2 CH.sub.3                                                                  H   SPh       CH                                     F          H    H  OCH.sub.3                                                                           SePh                                                                              SePh      CH                                     F          H    H  Br    H   SePh      CH                                     F          H    H  OCH.sub.3                                                                           H   OPh       CH                                     F          H    H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  OCH.sub.3                                                                           H   SPh       N                                      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  OCF.sub.2 H                                                                         H   SPh       CH                                     CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  OCH.sub.3                                                                           SCH.sub.3                                                                         SeCH.sub.3                                                                              CH                                     CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  OCH.sub.3                                                                           SPh SPh       N                                      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  CH.sub.3                                                                            SCH.sub.3                                                                         SeCH.sub.3                                                                              N                                      SO.sub.2 N(OCH).sub.3 CH.sub.3                                                           H    H  F     H   SPh       CH                                     SO.sub.2 N(OCH.sub.3).sub.3 CH.sub.3                                                     H    H  OCH.sub.3                                                                           SPh SPh       CH                                     OSO.sub.2 N(CH.sub.3).sub.2                                                              H    H  CF.sub.3                                                                            H   SeCH.sub.3                                                                              CH                                     SOCH.sub.3 H    H  OCH.sub.3                                                                           H   OPh       N                                      SOCH.sub.3 H    H  OCH.sub.2 CH.sub.3                                                                  H   SeCH.sub.3                                                                              N                                      SOCH.sub.3 H    H  OCH.sub.2 CH.sub.3                                                                  SeCH.sub.3                                                                        SeCH.sub.3                                                                              CH                                     SCF.sub.3  H    CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh       CH                                     SF.sub.3   3-OCH.sub.3                                                                        H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CH.sub.2 CHCH.sub.2                                                            5-CF.sub.3                                                                         H  OCH.sub.3                                                                           H   SPh       CH                                     OCH.sub.2 CHCCH                                                                          6-F  H  OCH.sub.3                                                                           H   SePh      CH                                     CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   CH.sub.2 OSi(CH.sub.3).sub.3                                                            CH 137-140                             Cl         H    H  CH.sub.3                                                                            H   CH.sub.2 OSi(CH.sub.3).sub.3                                                            CH 121-124                             CO.sub.2 C.sub.2 H.sub.5                                                                 H    H  CH.sub.3                                                                            H   CH.sub.2 OSi(CH.sub.3).sub.3                                                            CH                                     CF.sub.3   H    H  CH.sub.3                                                                            H   CH.sub.2 OSi(CH.sub.3).sub.3                                                            CH 102-105                             SO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   CH.sub.2 OSi(CH.sub.3).sub.3                                                            CH 176-178                             CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   CH.sub.2 OH                                                                             CH 138-141                             SO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                            H   CH.sub.2 OH                                                                             CH 156-158                             Cl         H    H  CH.sub.3                                                                            H   CH.sub.2 OH                                                                             CH 124-125                             CF.sub.3   H    H  CH.sub.3                                                                            H   CH.sub.2 OH                                                                             CH 126-127.5                           CO.sub.2 CH.sub. 3                                                                       H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     CH 111-114                             CO.sub.2 CH.sub.2 CH.sub.3                                                               H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     CH                                     Cl         H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     CH 169-171                             SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     CH 145-148                             CF.sub.3   H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     CH 139-141                             SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     CH 172-174                             Br         H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     CH 161-163                             NO.sub.2   H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     N                                      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     N                                      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                     N                                      CH.sub.3   H    H  OCH.sub.3                                                                           H   CH.sub.2 OH                                                                             N                                      F          H    H  OCH.sub.3                                                                           H   CH.sub.2 OH                                                                             N                                      __________________________________________________________________________

                  TABLE 1b                                                        ______________________________________                                         ##STR32##                                                                    R.sub.1      R.sub.2   R       X.sub.1                                                                             m.p. (°C.)                        ______________________________________                                        CO.sub.2 CH.sub.3                                                                          H         H       CH.sub.3                                                                            154-160                                  CO.sub.2 CH.sub.3                                                                          H         H       OCH.sub.3                                                                           136.5-141                                CO.sub.2 CH.sub.2 CH.sub.3                                                                 H         H       OCH.sub.3                                      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        H         H       OCH.sub.3                                      SO.sub.2 N(CH.sub.3).sub.2                                                                 H         H       CH.sub.3                                                                            173-178                                  SO.sub.2 N(CH.sub.3).sub.2                                                                 H         H       OCH.sub.3                                      CH.sub.2 CH.sub.3                                                                          H         H       OCH.sub.3                                      CH.sub.2 OCH.sub.3                                                                         H         H       OCH.sub.3                                      OCH.sub.2 CH.sub.2 OCH.sub.3                                                               H         H       OCH.sub.3                                      SO.sub.2 N(OCH.sub. 3)CH.sub.3                                                             H         H       OCH.sub.3                                      OSO.sub.2 CH.sub.3                                                                         H         H       CH.sub.3                                       OSO.sub.2 CH.sub.3                                                                         H         H       OCH.sub.3                                      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H         H       OCH.sub.3                                      Ph           H         H       OCH.sub.3                                       ##STR33##   H         H       OCH.sub.3                                       ##STR34##   H         H       OCH.sub.3                                       ##STR35##   H         H       OCH.sub.3                                      CO.sub.2 CH.sub.3                                                                          3-OCH.sub.3                                                                             H       OCH.sub.3                                      CO.sub.2 CH.sub.3                                                                          5-Cl      H       OCH.sub.3                                      SO.sub.2 N(CH.sub.3).sub.2                                                                 6-CF.sub.3                                                                              H       OCH.sub.3                                      CO.sub.2 CH.sub.3                                                                          H         CH.sub.3                                                                              OCH.sub.3                                      CO.sub.2 CH.sub.3                                                                          H         H       OCH.sub.3                                      CO.sub.2 CH.sub.3                                                                          H         H       CH.sub.3                                       SO.sub.2 N(CH.sub.3).sub.2                                                                 H         H       CH.sub.3                                       OSO.sub.2 CH.sub.3                                                                         H         H       OCH.sub.3                                      CH.sub.2 CH.sub.3                                                                          H         H       OCH.sub.3                                      CO.sub.2 CH.sub.3                                                                          3-OCH.sub.3                                                                             H       OCH.sub.3                                      ______________________________________                                    

                  TABLE 1c                                                        ______________________________________                                         ##STR36##                                                                    R.sub.1       R.sub.2    R      m.p. (°C.)                             ______________________________________                                        H             H          H                                                    CO.sub.2 CH.sub.3                                                                           H          H                                                    Cl            H          H      187-194                                       Br            H          H                                                    SO.sub.2 N(CH.sub.3).sub.2                                                                  H          H                                                    NO.sub.2      H          H                                                    CF.sub.3      H          H                                                    OSO.sub.2 CH.sub.3                                                                          H          H                                                    CH.sub.3      H          H                                                    CO.sub.2 CH.sub.2 CH.sub.3                                                                  H          H                                                    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H          H                                                    SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H          H                                                    CH.sub.2 CH.sub.3                                                                           H          H                                                    CH.sub.2 OCH.sub.3                                                                          H          H                                                    OCH.sub.3     H          H                                                    OCH.sub.2 CHCH.sub.2                                                                        H          H                                                    OCH.sub.2 C CH                                                                              H          H                                                    Ph            H          H                                                    CO.sub.2 CH.sub.3                                                                           3-OCH.sub.3                                                                              H                                                    SO.sub.2 N(CH.sub.3).sub.2                                                                  5-Cl       H                                                    CO.sub.2 CH.sub.3                                                                           6-CF.sub.3 H                                                    CO.sub.2 CH.sub.3                                                                           3-CH.sub.3 H                                                    CO.sub.2 CH.sub.3                                                                           H          CH.sub.3                                             ______________________________________                                    

                  TABLE 1d                                                        ______________________________________                                         ##STR37##                                                                    R.sub.1       R.sub.2    R      m.p. (°C.)                             ______________________________________                                        CO.sub.2 CH.sub.3                                                                           H          H      153-161                                       Cl            H          H      158-162                                       Br            H          H                                                    SO.sub.2 N(CH.sub.3).sub.2                                                                  H          H      138-142                                       NO.sub.2      H          H      180-190                                       CF.sub.3      H          H                                                    OSO.sub.2 CH.sub.3                                                                          H          H      173-178                                       CH.sub.3      H          H      133-153                                       CO.sub.2 CH.sub.2 CH.sub.3                                                                  H          H      103-107                                       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H          H                                                    SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H          H                                                    CH.sub.2 CH.sub.3                                                                           H          H                                                    CH.sub.2 OCH.sub.3                                                                          H          H                                                    OCH.sub.3     H          H                                                    Ph            H          H                                                    CO.sub.2 CH.sub. 3                                                                          3-OCH.sub.3                                                                              H                                                    SO.sub.2 N(CH.sub.3).sub.2                                                                  5-Cl       H                                                    CO.sub.2 CH.sub.3                                                                           6-CF.sub.3 H                                                    CO.sub.2 CH.sub.3                                                                           6-CH.sub.3 H                                                    CO.sub.2 CH.sub.3                                                                           H          CH.sub.3                                             SCH.sub.3     H          H                                                    SO.sub.2 CH.sub.3                                                                           H          H      200-205                                       SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         H          H      195-200                                       ______________________________________                                    

                  TABLE 1e                                                        ______________________________________                                         ##STR38##                                                                                                              m.p.                                R.sub.1    R.sub.2  R      X.sub.1                                                                             E   Z    (°C.)                        ______________________________________                                        OCH.sub.2 CH.sub.3                                                                       H        H      CH.sub.3                                                                            F   CH                                       OCH.sub.2 CH.sub.2 CH.sub.3                                                              H        H      CH.sub.3                                                                            F   CH                                       SO.sub.2 N(CH.sub.3).sub.2                                                               H        H      CH.sub.3                                                                            F   CH   221-224                             SO.sub.2 N(CH.sub.3).sub.2                                                               H        H      OCH.sub.3                                                                           F   CH   215-220                             SO.sub.2 N(CH.sub.3).sub.2                                                               H        H      OCH.sub.3                                                                           F   N                                        SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H        H      OCH.sub.3                                                                           F   CH                                       SO.sub.2 N(OCH.sub.3)CH.sub.3                                                            H        H      CH.sub.3                                                                            F   CH                                       OCH.sub.2 CH.sub.2 CH.sub.3                                                              H        H      OCH.sub.3                                                                           Cl  CH                                       SO.sub.2 N(CH.sub.3).sub.2                                                               H        H      OCH.sub.3                                                                           Br  CH                                       SO.sub.2 (CH.sub.3).sub.2                                                                H        H      OCH.sub.3                                                                           Br  N                                         ##STR39## H        H      OCH.sub.3                                                                           F   CH                                       SO.sub.2 N(CH.sub.3).sub.2                                                               3-OCH.sub.3                                                                            H      OCH.sub.3                                                                           F   CH                                       SO.sub.2 N(CH.sub.3).sub.2                                                               6-CF.sub.3                                                                             H      OCH.sub.3                                                                           F   CH                                       SO.sub.2 N(CH.sub.3).sub.2                                                               H        CH.sub.3                                                                             OCH.sub.3                                                                           F   CH                                       SO.sub.2 N(CH.sub.3).sub.2                                                               H        H      OCH.sub.3                                                                           F   N                                        SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                      H        H      CH.sub.3                                                                            F   N                                        CH.sub.2 CH.sub.3                                                                        H        H      OCH.sub.3                                                                           F   N                                        ______________________________________                                    

                                      TABLE 1f                                    __________________________________________________________________________     ##STR40##                                                                    R.sub.1    R.sub.2                                                                            R  X.sub.1                                                                           Z  G          m.p. (°C.)                        __________________________________________________________________________    CH.sub.3   H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            CH.sub.3   H    H  CH.sub.3                                                                          N  CH(OCH.sub.3).sub.2                                 C.sub.2 H.sub.5                                                                          H    CH.sub.3                                                                         OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 C.sub.2 H.sub.5                                                                          H    H  OCH.sub.3                                                                         CH CH(OC.sub.2 H.sub.5).sub.2                          CH(CH.sub.3).sub.2                                                                       H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            CH(CH.sub.3)C.sub.2 H.sub.5                                                              H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            OCH.sub.3  H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            OCH.sub.3  5-Cl H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                            OC.sub.2 H.sub.5                                                                         H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            OCH(CH.sub.3).sub.2                                                                      H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 OC.sub.4 H.sub.9 -n                                                                      H    H  OCH.sub.3                                                                         N  CH(OCH.sub.3).sub.2                                 OCH.sub.2 CH.sub.2 OCH.sub.3                                                             H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 F          H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                            Cl         H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                                                                 115-118                                  Cl         H    H  OC.sub.2 H.sub.5                                                                  CH CH(OCH.sub.2 CH.sub.2 O)                            Cl         H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 Br         5-CH.sub.3                                                                         H  CH.sub.3                                                                          CH CH(OCH.sub.3).sub.2                                 NO.sub.2   H    H  OCH.sub.3                                                                         CH CH(OC.sub.2 H.sub.5).sub.2                          NO.sub.2   H    CH.sub.3                                                                         CH.sub.3                                                                          CH CH(OCH.sub.3).sub.2                                 CF.sub.3   H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            CO.sub.2 CH.sub. 3                                                                       H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                                                                 102-104                                  CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                                                                 148-150                                  CO.sub.2 CH.sub.3                                                                        H    H  OC.sub.2 H.sub.5                                                                  CH CH(OCH.sub.2 CH.sub.2 O)                            CO.sub.2 CH.sub.3                                                                        5-OCH.sub.3                                                                        H  OCH.sub.3                                                                         N  CH(OCH.sub.3).sub.2                                 CO.sub.2 C.sub.2 H.sub.5                                                                 H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 CO.sub.2 CH.sub.2 CHCH.sub.2                                                             H    H  CH.sub.3                                                                          CH CH(OC.sub.2 H.sub.5).sub.2                          CO.sub.2 C.sub.4 H.sub.9 -n                                                              H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                                                                 122-124                                  SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                                                                 .sup.  183-185(d)                        SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OC.sub.2 H.sub.5                                                                  CH CH(OCH.sub.3).sub.2                                 SO.sub.2 N(CH.sub.3)C.sub.2 H.sub.5                                                      3-CF.sub.3                                                                         H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 OSO.sub.2 CH.sub. 3                                                                      H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 OSO.sub.2 C.sub.2 H.sub.5                                                                H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                            SCF.sub.3  H    H  OC.sub.2 H.sub.5                                                                  CH CH(OCH.sub.3).sub.2                                 OCHF.sub.2 H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 CO.sub.2 C.sub.2 H.sub.5                                                                 H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                                                                 151-153                                  CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                         N  CH(OCH.sub.3).sub.2                                 CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                         CH CH(OC.sub.2 H.sub.5).sub.2                          CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                          CH CH(OCH.sub.3).sub.2                                 SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                                                                 191-194                                  SO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                                                                 .sup.  194-196(d)                        SO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                          CH CH(OCH.sub.3).sub.2                                 SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 SO.sub.2 C.sub.2 H.sub.5                                                                 H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            SO.sub.2 CH.sub. 2 CH.sub.2 CH.sub.3                                                     H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                            SO.sub.2 CH.sub.2 CHCH.sub.2                                                             H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 SO.sub.2 C.sub.2 H.sub.5                                                                 H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 OCH.sub.2 CCH                                                                            H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            OCH.sub.2 CCCH.sub.3                                                                     H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                            OCH.sub.2 CHCH.sub.2                                                                     H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            OCH.sub.2 CH.sub.2 CHCH.sub.2                                                            H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            CH.sub.2 OCH.sub.3                                                                       H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            CH.sub.2 OC.sub.2 H.sub.5                                                                H    H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                 C.sub.6 H.sub.5                                                                          6-Cl H  CH.sub.3                                                                          CH CH(OC.sub.2 H.sub.5).sub.2                          C.sub.6 H.sub.5                                                                          6-OCH.sub.3                                                                        H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                  ##STR41## H    H  OCH.sub.3                                                                         N  CH(OCH.sub.2 CH.sub.2 O)                             ##STR42## H    H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                             ##STR43## H    H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                            CO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                         CH C.sub.6 H.sub.5                                                                          110-112(d)                               CO.sub.2 CH.sub.3                                                                        H    H  CH.sub.3                                                                          CH C.sub.6 H.sub.5                                     SO.sub.2 N(CH.sub.3).sub.2                                                               H    H  OCH.sub.3                                                                         CH C.sub.6 H.sub.5                                     SO.sub.2 CH.sub.3                                                                        H    H  OCH.sub.3                                                                         N  C.sub.6 H.sub.5                                     Cl         H    H  OCH.sub.3                                                                         CH C.sub.6 H.sub.5                                     OCHF.sub.2 H    H  OCH.sub.3                                                                         CH C.sub.6 H.sub.5                                     __________________________________________________________________________

                                      TABLE 2a                                    __________________________________________________________________________     ##STR44##                                                                    L  R.sub.3                                                                              R.sub.4  R  X     T   Y       Z  m.p. (°C.)                  __________________________________________________________________________    L-2                                                                              CH.sub.3                                                                             --       H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                    L-2                                                                              CH.sub.3                                                                             --       H  OCH.sub.3                                                                           H   SePh    CH                                    L-2                                                                              OCH.sub.3                                                                            --       H  CH.sub.3                                                                            H   SPh     CH                                    L-2                                                                              OCH.sub.3                                                                            --       H  OCH.sub.3                                                                           SPh SPh     CH                                    L-2                                                                              OCH.sub.3                                                                            --       H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                            CH                                    L-2                                                                              F      --       H  OCH.sub.3                                                                           H   SPh     N                                     L-2                                                                              F      --       H  Cl    H   SPh     CH                                    L-2                                                                              Cl     --       H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                    L-2                                                                              Cl     --       H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            N                                     L-2                                                                              Br     --       H  CH.sub.3                                                                            SPh SPh     N                                     L-2                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                           --       H  OCH.sub.3                                                                           H   OPh     CH                                    L-2                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                           --       H  Br    H   SePh    CH                                    L-2                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                           --       H  OCH.sub.3                                                                           H   SePh    CH                                    L-2                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                           --       H  CH.sub.3                                                                            SeCH.sub.3                                                                        SeCH.sub.3                                                                            CH                                    L-2                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                           --       H  OCH.sub.3                                                                           H   SPh     N                                     L-2                                                                              OSO.sub.2 CH.sub.3                                                                   --       H  OCH.sub.3                                                                           SPh SPh     N                                     L-2                                                                              OSO.sub.2 CH.sub.3                                                                   --       H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                           N                                     L-2                                                                              SOCH.sub.3                                                                           --       H  F     H   OPh     CH                                    L-2                                                                              SOCH.sub.3                                                                           --       H  OCH.sub.3                                                                           H   SPh     CH                                    L-2                                                                              SCH.sub.3                                                                            --       H  OCH.sub.3                                                                           H   SePh    CH                                    L-2                                                                              SCH.sub.3                                                                            --       H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                    L-2                                                                              SO.sub.2 CH.sub.3                                                                    --       H  CH.sub.3                                                                            SeCH.sub.3                                                                        SePh    CH                                    L-2                                                                              SO.sub.2 CH.sub.3                                                                    --       H  OCH.sub.3                                                                           H   SPh     CH                                    L-2                                                                              SO.sub.2 CH.sub.3                                                                    --       H  OCH.sub.3                                                                           H   SPh     N                                     L-2                                                                              CH.sub.3                                                                             --       H  OCH.sub.2 CH.sub.3                                                                  H   SPh     CH                                    L-2                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                           --       H  CH.sub.3                                                                            H   CH.sub.2 OSi(CH.sub.3).sub.3                                                          CH                                    L-2                                                                              CH.sub.3                                                                             --       H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                    L-2                                                                              OCH.sub.3                                                                            --       CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh     CH                                    L-3                                                                              --     CH.sub.3 H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                    L-3                                                                              --     CH.sub.3 H  OCH.sub.3                                                                           H   SePh    CH                                    L-3                                                                              --     CH.sub.2 CH.sub.3                                                                      H  CH.sub.3                                                                            H   SPh     CH                                    L-3                                                                              --     OCH.sub.3                                                                              H  OCH.sub.3                                                                           SPh SPh     CH                                    L-3                                                                              --     OCH.sub.3                                                                              H  OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                            CH                                    L-3                                                                              --     F        H  OCH.sub.3                                                                           H   SPh     N                                     L-3                                                                              --     F        H  Cl    H   SPh     CH                                    L-3                                                                              --     Cl       H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                    L-3                                                                              --     Cl       H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            N                                     L-3                                                                              --     Br       H  CH.sub.3                                                                            SPh SPh     N                                     L-3                                                                              --     Br       H  OCH.sub.3                                                                           H   OPh     CH                                    L-3                                                                              --     OCH.sub.2 CH.sub.3                                                                     H  Br    H   SePh    CH                                    L-3                                                                              --     SO.sub.2 N(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           H   SePh    CH                                    L-3                                                                              --     SO.sub.2 N(CH.sub.3).sub.2                                                             H  CH.sub.3                                                                            SeCH.sub.3                                                                        SeCH.sub. 3                                                                           CH                                    L-3                                                                              --     SO.sub.2 N(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           H   SPh     N                                     L-3                                                                              --     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                    H  OCH.sub.3                                                                           SPh SPh     N                                     L-3                                                                              --     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                    H  OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                           N                                     L-3                                                                              --     SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           H   SePh    CH                                    L-3                                                                              --     SCH.sub.3                                                                              H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                    L-3                                                                              --     SCH.sub.3                                                                              H  CH.sub.3                                                                            SeCH.sub.3                                                                        SePh    CH                                    L-3                                                                              --     SOCH.sub.3                                                                             H  OCH.sub.3                                                                           H   SPh     CH                                    L-3                                                                              --     SO.sub.2 CH.sub.3                                                                      H  OCH.sub.3                                                                           H   SPh     N                                     L-3                                                                              --     SO.sub.2 CH.sub.3                                                                      H  OCH.sub.2 CH.sub.3                                                                  H   SPh     CH                                    L-3                                                                              --     SO.sub.2 CH.sub.3                                                                      H  OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                    L-3                                                                              --     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           H   SPh     CH                                    L-3                                                                              --     CH.sub.3 H  OCH.sub.3                                                                           H   CH.sub.2 OH                                                                           CH                                    __________________________________________________________________________

                  TABLE 2b                                                        ______________________________________                                         ##STR45##                                                                                                              m.p.                                L    R.sub.3    R.sub.4      R    X.sub.1 (°C.)                        ______________________________________                                        L-2  SO.sub.2 N(CH.sub.3).sub.2                                                               --           H    CH.sub.3                                    L-2  SO.sub.2 N(CH.sub.3).sub.2                                                               --           H    OCH.sub.3                                   L-2  SO.sub.2 N(CH.sub.3).sub.2                                                               --           H    OCH.sub.3                                   L-2  CH.sub.3   --           H    CH.sub.3                                    L-2  CH.sub.3   --           H    OCH.sub.3                                   L-2  CH.sub.3   --           H    OCH.sub.2 CH.sub.3                          L-2  H          --           H    OCH.sub.3                                   L-2  H          --           H    OCH.sub.3                                   L-2  F          --           H    OCH.sub.3                                   L-2  Cl         --           H    OCH.sub.3                                   L-2  Cl         --           H    CH.sub.3                                    L-2  Br         --           H    OCH.sub.3                                   L-2  OSO.sub.2 CH.sub.3                                                                       --           H    OCH.sub.3                                   L-2  OSO.sub.2 CH.sub.3                                                                       --           H    CH.sub.3                                    L-2  SCH.sub.3  --           H    CH.sub.3                                    L-2  SCH.sub.3  --           H    OCH.sub.3                                   L-2  SOCH.sub.3 --           H    OCH.sub.3                                   L-2  SOCH.sub.3 --           H    OCH.sub.3                                   L-2  SO.sub.2 CH.sub.3                                                                        --           H    CH.sub.3                                    L-2  SO.sub.2 CH.sub.3                                                                        --           H    OCH.sub.3                                   L-2  SO.sub.2 N(CH.sub.3).sub.2                                                               --           H    OCH.sub.2 CH.sub.3                          L-2  OSO.sub.2 CH.sub.3                                                                       --           H    CH.sub.3                                    L-2  SO.sub.2 N(CH.sub.3).sub.2                                                               --           CH.sub.3                                                                           OCH.sub.2 CH.sub.3                          L-2  H          --           CH.sub.3                                                                           OCH.sub.3                                   L-3  --         CH.sub.3     H    CH.sub.3                                    L-3  --         CH.sub.3     H    OCH.sub.3                                   L-3  --         CH.sub.3     H    OCH.sub.3                                   L-3  --         CH.sub.2 CH.sub.3                                                                          H    OCH.sub.3                                   L-3  --         CH.sub.2 CH.sub.3                                                                          H    CH.sub.3                                    L-3  --         OCH.sub.3    H    OCH.sub.3                                   L-3  --         OCH.sub.3    H    OCH.sub.2 CH.sub.3                          L-3  --         F            H    OCH.sub.3                                   L-3  --         F            H    OCH.sub.3                                   L-3  --         Cl           H    OCH.sub.3                                   L-3  --         Cl           H    OCH.sub.3                                   L-3  --         Br           H    CH.sub.3                                    L-3  --         Br           H    OCH.sub.3                                   L-3  --         OCH.sub.2 CH.sub.3                                                                         H    OCH.sub.3                                   L-3  --         OCH.sub.2 CH.sub.3                                                                         H    CH.sub.3                                    L-3  --         SO.sub.2 N(CH.sub.3).sub.2                                                                 H    CH.sub.3                                    L-3  --         SO.sub.2 N(CH.sub.3).sub.2                                                                 H    OCH.sub.3                                   L-3  --         SO.sub.2 N(CH.sub.3).sub.2                                                                 H    OCH.sub.3                                   L-3  --         SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                        H    OCH.sub.3                                   L-3  --         SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                        H    CH.sub.3                                    L-3  --         SO.sub.2 N(OCH.sub.3)CH.sub.3                                                              H    OCH.sub.3                                   L-3  --         SCH.sub.3    CH.sub.3                                                                           OCH.sub.2 CH.sub.3                          L-3  --         SO.sub.2 CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                   ______________________________________                                    

                  TABLE 2c                                                        ______________________________________                                         ##STR46##                                                                    L    R.sub.3     R.sub.4       R     m.p. (°C.)                        ______________________________________                                        L-2  H           --            H                                              L-2  CH.sub.3    --            H                                              L-2  OCH.sub.3   --            H                                              L-2  F           --            H                                              L-2  Cl          --            H                                              L-2  Br          --            H                                              L-2  SO.sub.2 N(CH.sub.3).sub.2                                                                --            H                                              L-2  OSO.sub.2 CH.sub.3                                                                        --            H                                              L-2  SCH.sub.3   --            H                                              L-2  SOCH.sub.3  --            H                                              L-2  SO.sub.2 CH.sub.3                                                                         --            H                                              L-2  CH.sub.3    --            CH.sub.3                                       L-3  --          CH.sub.3      H                                              L-3  --          CH.sub.2 CH.sub.3                                                                           H                                              L-3  --          OCH.sub.3     H                                              L-3  --          OCH.sub.2 CH.sub.3                                                                          H                                              L-3  --          F             H                                              L-3  --          Cl            H                                              L-3  --          Br            H                                              L-3  --          SO.sub.2 N(CH.sub.3).sub.2                                                                  H                                              L-3  --          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H                                              L-3  --          SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H                                              L-3  --          SCH.sub.3     H                                              L-3  --          SO.sub.2 CH.sub.3                                                                           H                                              L-3  --          CH.sub.3      CH.sub.3                                       ______________________________________                                    

                  TABLE 2d                                                        ______________________________________                                         ##STR47##                                                                    L    R.sub.3     R.sub.4       R     m.p. (°C.)                        ______________________________________                                        L-2  H           --            H                                              L-2  CH.sub.3    --            H                                              L-2  OCH.sub.3   --            H                                              L-2  F           --            H                                              L-2  Cl          --            H                                              L-2  Br          --            H                                              L-2  SO.sub.2 N(CH.sub.3).sub.2                                                                --            H                                              L-2  OSO.sub.2 CH.sub.3                                                                        --            H                                              L-2  SCH.sub.3   --            H                                              L-2  SOCH.sub.3  --            H                                              L-2  SO.sub.2 CH.sub.3                                                                         --            H                                              L-2  CH.sub.3    --            CH.sub.3                                       L-3  --          CH.sub.3      H                                              L-3  --          CH.sub.2 CH.sub.3                                                                           H                                              L-3  --          OCH.sub.3     H                                              L-3  --          OCH.sub.2 CH.sub.3                                                                          H                                              L-3  --          F             H                                              L-3  --          Cl            H                                              L-3  --          Br            H                                              L-3  --          SO.sub.2 N(CH.sub.3).sub.2                                                                  H                                              L-3  --          SO.sub.2 N(CH.sub.2 CH.sub. 3).sub.2                                                        H                                              L-3  --          SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H                                              L-3  --          SCH.sub.3     H                                              L-3  --          SO.sub.2 CH.sub.3                                                                           H                                              L-3  --          CH.sub.3      CH.sub.3                                       ______________________________________                                    

                  TABLE 2e                                                        ______________________________________                                         ##STR48##                                                                                                              m.p.                                L  R.sub.3 R.sub.4      R      X.sub.1                                                                             E   Z (°C.)                       ______________________________________                                        L-2 H      --           H      OCH.sub.3                                                                           F   CH                                   L-2 CH.sub.3                                                                             --           H      OCH.sub.3                                                                           F   CH                                   L-2 CH.sub.3                                                                             --           H      OCH.sub.3                                                                           Cl  CH                                   L-2 OCH.sub.3                                                                            --           H      CH.sub.3                                                                            F   CH                                   L-2 F      --           H      OCH.sub.3                                                                           F   CH                                   L-2 Cl     --           H      OCH.sub.3                                                                           F   CH                                   L-2 Cl     --           H      OCH.sub.3                                                                           Cl  CH                                   L-2 Br     --           H      CH.sub.3                                                                            F   N                                    L-2 SO.sub.2 N(CH.sub.3).sub.2                                                           --           H      OCH.sub.3                                                                           F   CH                                   L-2 SO.sub.2 N(CH.sub.3).sub.2                                                           --           H      OCH.sub.3                                                                           Br  CH                                   L-2 OSO.sub.2 CH.sub.3                                                                   --           H      OCH.sub.3                                                                           F   CH                                   L-3 --     CH.sub.2 CH.sub.3                                                                          H      OCH.sub.3                                                                           F   CH                                   L-3 --     OCH.sub.3    H      OCH.sub.3                                                                           F   N                                    L-3 --     F            H      CH.sub.3                                                                            F   CH                                   L-3 --     Br           H      OCH.sub.3                                                                           Br  CH                                   L-3 --     SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                        H      OCH.sub.3                                                                           F   CH                                   L-3 --     SO.sub.2 N(CH.sub.3).sub.2                                                                 H      OCH.sub.3                                                                           F   N                                    L-3 --     SCH.sub.3    H      CH.sub.3                                                                            Cl  CH                                   L-3 --     SO.sub.2 CH.sub.3                                                                          H      OCH.sub.3                                                                           F   CH                                   L-3 --     CH.sub.3     CH.sub.3                                                                             OCH.sub.3                                                                           F   CH                                   L-3 --     OCH.sub.2 CH.sub.3                                                                         CH.sub.3                                                                             CH.sub.3                                                                            Br  N                                    ______________________________________                                    

                                      TABLE 2f                                    __________________________________________________________________________     ##STR49##                                                                    L   R.sub.3                                                                              R.sub.4                                                                            R   X   Z   G          m.p. (°C.)                      __________________________________________________________________________    L-2 Cl     --   H   OCH.sub.3                                                                         CH  CH(OCH.sub.2 CH.sub.2 O)                          L-2 Cl     --   H   CH.sub.3                                                                          CH  CH(OCH.sub.3).sub.2                               L-2 OCH.sub.3                                                                            --   H   OCH.sub.3                                                                         CH  CH(OCH.sub.3).sub.2                               L-2 OCH.sub.3                                                                            --   H   CH.sub.3                                                                          CH  CH(OCH.sub.2 CH.sub.2 O)                          L-2 OSO.sub.2 CH.sub.3                                                                   --   H   OCH.sub.3                                                                         CH  CH(OCH.sub.2 CH.sub.2 O)                          L-2 SO.sub.2 CH.sub.3                                                                    --   CH.sub.3                                                                          OCH.sub.3                                                                         CH  CH(OCH.sub.3).sub.2                               L-2 SCH.sub.3                                                                            --   H   OCH.sub.3                                                                         N   CH(OCH.sub.2 CH.sub.2 O)                          L-2 Br     --   H   OCH.sub.3                                                                         CH  CH(OCH.sub.2 CH.sub.2 O)                          L-2 SO.sub.2 N(CH.sub.3).sub.2                                                           --   H   OCH.sub.3                                                                         CH  CH(OCH.sub.2 CH.sub.2 O)                          L-2 CH.sub.3                                                                             --   H   OCH.sub.3                                                                         CH  CH(OCH.sub.2 CH.sub.2 O)                          L-3 --     CH.sub.3                                                                           H   OCH.sub.3                                                                         CH  CH(OCH.sub.2 CH.sub.2 O)                          L-3 --     OCH.sub.3                                                                          H   OCH.sub.3                                                                         CH  CH(OCH.sub.3).sub.2                               L-3 --     OC.sub.2 H.sub.5                                                                   H   CH.sub.3                                                                          N   CH(OC.sub.2 H.sub.5).sub.2                        L-3 --     Cl   H   CH.sub.3                                                                          CH  CH(OCH.sub.2 CH.sub.2 O)                          L-3 --     SO.sub.2 C.sub.2 H.sub.5                                                           H   OCH.sub.3                                                                         CH  CH(OCH.sub.2 CH.sub.2 O)                          L-3 --     SO.sub.2 CH.sub.3                                                                  H   OCH.sub.3                                                                         CH  CH(OCH.sub.2 CH.sub.2 O)                          L-2 Cl     --   H   OCH.sub.3                                                                         CH  C.sub.6 H.sub.5                                   L-2 OCH.sub.3                                                                            --   H   OCH.sub.3                                                                         N   C.sub.6 H.sub.5                                   L-3 --     SO.sub.2 CH.sub.3                                                                  H   CH.sub.3                                                                          CH  C.sub.6 H.sub.5                                   L-3 --     Cl   H   OCH.sub.3                                                                         CH  C.sub.6 H.sub.5                                   __________________________________________________________________________

                                      TABLE 3a                                    __________________________________________________________________________     ##STR50##                                                                    L   R.sub.5   R   X      T    Y        Z   m.p. (°C.)                  __________________________________________________________________________    L-4 CH.sub.3  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 CH.sub.3  H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 CH.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 CH.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SOPh     CH                                     L-4 F         H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-4 Cl        H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-4 Cl        H   CH.sub.3                                                                             H    SePh     CH                                     L-4 Br        H   CH.sub.3                                                                             H    SPh      CH                                     L-4 Br        H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-4 NO.sub.2  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 NO.sub.2  H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 NO.sub.2  H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 NO.sub.2  H   OCH.sub. 3                                                                           H    SO.sub.2 Ph                                                                            CH                                     L-4 NO.sub.2  H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-4 NO.sub.2  H   CH.sub.3                                                                             H    SPh      CH                                     L-4 NO.sub.2  H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-4 NO.sub.2  H   OCH.sub.3                                                                            H    OPh      CH                                     L-4 NO.sub.2  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-4 NO.sub.2  H   OCH.sub.3                                                                            H    SPh      N                                      L-4 NO.sub.2  H   CH.sub.3                                                                             SePh SePh     N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SOPh     CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    OPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SePh     CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SePh SePh     N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SPh  SPh      N                                      L-4 CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                          OCH.sub.3                                                                            H    SePh     CH                                     L-4 CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                          OCH.sub.3                                                                            H    SPH      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SePh     CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SOPh     CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SePh     CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SPh  SO.sub.2 Ph                                                                            CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SePh     N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            N                                      L-4 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    OPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.2 CH.sub.3                                                                   H    SPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   F      H    SPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   Cl     H    SPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CF.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   CF.sub.3                                                                             H    SePh     CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCHF.sub.2                                                                           H    SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   OCHF.sub.2                                                                           H    SPh      CH                                     L-4 CO.sub.2 CH.sub.3                                                                       H   Br     H    SPh      CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-4 CO.sub.2 CH.sub. 2 CH.sub.3                                                             H   CH.sub.3                                                                             H    SPh      N                                      L-4 CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SePh     CH                                     L-4 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SPh      CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SPh      N                                      L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SePh SePh     CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    OPh      CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SePh     CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SPh      CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-4 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             SPh  SPh      CH                                     L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SePh     N                                      L-4 SO.sub.2 N(CH.sub.2 CH.sub.3 ).sub.2                                                    H   OCH.sub.3                                                                            H    SPh      N                                      L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-4 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SPh      CH                                     L-4 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-4 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   CH.sub.3                                                                             H    SePh     CH                                     L-4 SCH.sub.3 H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 SCH.sub.3 H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 SCH.sub.3 H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 SOCH.sub.3                                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-4 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     CH                                     L-4 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-4 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-4 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     N                                      L-5 CH.sub.3  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 CH.sub.3  H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 CH.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 CH.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SOPh     CH                                     L-5 F         H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-5 Cl        H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-5 Cl        H   CH.sub.3                                                                             H    SePh     CH                                     L-5 Br        H   CH.sub.3                                                                             H    SPh      CH                                     L-5 Br        H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-5 NO.sub.2  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 NO.sub.2  H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 NO.sub.2  H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 NO.sub.2  H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-5 NO.sub.2  H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-5 NO.sub.2  H   CH.sub.3                                                                             H    SPh      CH                                     L-5 NO.sub.2  H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-5 NO.sub.2  H   OCH.sub.3                                                                            H    OPh      CH                                     L-5 NO.sub.2  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-5 NO.sub.2  H   OCH.sub.3                                                                            H    SPh      N                                      L-5 NO.sub.2  H   CH.sub.3                                                                             SePh SePh     N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SOPh     CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    OPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SePh     CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SePh SePh     N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SPh  SPh      N                                      L-5 CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                          OCH.sub.3                                                                            H    SePh     CH                                     L-5 CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                          OCH.sub.3                                                                            H    SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SePh     CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SOPh     CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SePh     CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SPh  SO.sub.2 Ph                                                                            CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SePh     N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            N                                      L-5 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    OPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.2 CH.sub.3                                                                   H    SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   F      H    SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   Cl     H    SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CF.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   CF.sub.3                                                                             H    SePh     CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCHF.sub.2                                                                           H    SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   OCHF.sub.2                                                                           H    SPh      CH                                     L-5 CO.sub.2 CH.sub.3                                                                       H   Br     H    SPh      CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SPh      N                                      L-5 CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SePh     CH                                     L-5 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SPh      CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SPh      N                                      L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SePh SePh     CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    OPh      CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SePh     CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SPh      CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-5 SO.sub.2 N(CH.sub. 3).sub.2                                                             H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-5 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             SPh  SPh      CH                                     L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SePh     N                                      L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SPh      N                                      L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-5 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SPh      CH                                     L-5 SO.sub.2 N(OCH.sub.3)CH.sub. 3                                                          H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-5 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   CH.sub.3                                                                             H    SePh     CH                                     L-5 SCH.sub.3 H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 SCH.sub.3 H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 SCH.sub.3 H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 SOCH.sub.3                                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-5 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     CH                                     L-5 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-5 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-5 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     N                                      L-6 CH.sub.3  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 CH.sub.3  H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 CH.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 CH.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SOPh     CH                                     L-6 F         H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-6 Cl        H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-6 Cl        H   CH.sub.3                                                                             H    SePh     CH                                     L-6 Br        H   CH.sub.3                                                                             H    SPh      CH                                     L-6 Br        H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-6 NO.sub.2  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 NO.sub.2  H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 NO.sub.2  H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 NO.sub.2  H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-6 NO.sub.2  H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-6 NO.sub.2  H   CH.sub.3                                                                             H    SPh      CH                                     L-6 NO.sub.2  H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-6 NO.sub.2  H   OCH.sub.3                                                                            H    OPh      CH                                     L-6 NO.sub.2  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-6 NO.sub.2  H   OCH.sub.3                                                                            H    SPh      N                                      L-6 NO.sub.2  H   CH.sub.3                                                                             SePh SePh     N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SOPh     CH                                     L-6 CO.sub.2 CH.sub. 3                                                                      H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    OPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SePh     CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SePh SePh     N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            SPh  SPh      N                                      L-6 CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                          OCH.sub.3                                                                            H    SePh     CH                                     L-6 CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                          OCH.sub.3                                                                            H    SPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SePh     CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SPh      CH                                     L-6 CO.sub.2 CH.sub. 3                                                                      H   CH.sub.3                                                                             H    SOPh     CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SePh     CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SeCH.sub.3                                                                         SPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             SPh  SO.sub.2 Ph                                                                            CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SePh     N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   CH.sub.3                                                                             H    OPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.2 CH.sub.3                                                                   H    SPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   F      H    SPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   Cl     H    SPh      CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CF.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   CF.sub.3                                                                             H    SePh     CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCHF.sub.2                                                                           H    SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCHF.sub.2                                                                           H    SPh      CH                                     L-6 CO.sub.2 CH.sub. 3                                                                      H   Br     H    SPh      CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SPh      N                                      L-6 CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SePh     CH                                     L-6 CO.sub.2 CH.sub.2 CH.sub.3                                                              H   CH.sub.3                                                                             H    SPH      CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 SO.sub. 2 N(CH.sub.3).sub.2                                                             H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    SPh      N                                      L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SePh SePh     CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            SPh  SPh      CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   OCH.sub.3                                                                            H    OPh      CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SePh     CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SPh      CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                            CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             SeCH.sub.3                                                                         SeCH.sub.3                                                                             CH                                     L-6 SO.sub.2 N(CH.sub.3).sub.2                                                              H   CH.sub.3                                                                             SPh  SPh      CH                                     L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 SO.sub.2 N(CH.sub.2 CH.sub.3 ).sub.2                                                    H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             N                                      L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SePh     N                                      L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   OCH.sub.3                                                                            H    SPh      N                                      L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             N                                      L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SeCH.sub.3                                                                             CH                                     L-6 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                     H   CH.sub.3                                                                             H    SPh      CH                                     L-6 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-6 SO.sub.2 N(OCH.sub.3)CH.sub.3                                                           H   CH.sub.3                                                                             H    SePh     CH                                     L-6 SCH.sub.3 H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 SCH.sub.3 H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 SCH.sub.3 H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 SOCH.sub.3                                                                              H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                             CH                                     L-6 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     CH                                     L-6 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SPh      CH                                     L-6 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SO.sub.2 Ph                                                                            CH                                     L-6 SO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    SePh     N                                      L-4 CH.sub.3  H   OCH.sub.3                                                                            H    CH.sub.2 OH                                                                            CH                                     L-5 Br        H   OCH.sub.3                                                                            H    CH.sub.2 OSi(CH.sub.3).sub.3                                                           CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    CH.sub.2 OSi(CH.sub.3).sub.3                                                           CH                                     L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    CH.sub.2 OH                                                                            N                                      L-6 CO.sub.2 CH.sub.3                                                                       H   OCH.sub.3                                                                            H    OSi(CH.sub.3).sub.3                                                                    N                                      __________________________________________________________________________

                  TABLE 3b                                                        ______________________________________                                         ##STR51##                                                                    L     R.sub.5       R       X.sub.1  m.p. (°C.)                        ______________________________________                                        L-4   CH.sub.3      H       CH.sub.3                                          L-4   CH.sub.3      H       OCH.sub.3                                         L-4   CH.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-4   CH.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-4   CH.sub.2 CH.sub.2 CH.sub.3                                                                  H       OCH.sub.3                                         L-4   F             H       OCH.sub.3                                         L-4   Cl            H       OCH.sub.3                                         L-4   Cl            H       CH.sub.3                                          L-4   Br            H       OCH.sub.3                                         L-4   NO.sub.2      H       CH.sub.3                                          L-4   NO.sub.2      H       OCH.sub.3                                         L-4   NO.sub.2      H       OCH.sub.2 CH.sub.3                                L-4   CO.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-4   CO.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-4   CO.sub.2 CH.sub.3                                                                           H       OCH.sub.2 CH.sub.3                                L-4   CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                              OCH.sub.3                                         L-4   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       CH.sub.3                                          L-4   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       OCH.sub.3                                         L-4   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       OCH.sub.2 CH.sub.3                                L-4   SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H       OCH.sub.3                                         L-4   SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H       OCH.sub.3                                         L-4   SCH.sub.3     H       OCH.sub.3                                         L-4   SOCH.sub.3    H       OCH.sub.3                                         L-4   SO.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-4   SO.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-4   SO.sub.2 CH.sub.3                                                                           H       OCH.sub.2 CH.sub.3                                L-5   CH.sub.3      H       CH.sub.3                                          L-5   CH.sub.3      H       OCH.sub.3                                         L-5   CH.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-5   CH.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-5   CH.sub.2 CH.sub.2 CH.sub.3                                                                  H       OCH.sub.3                                         L-5   F             H       OCH.sub.3                                         L-5   Cl            H       OCH.sub.3                                         L-5   Cl            H       CH.sub.3                                          L-5   Br            H       OCH.sub.3                                         L-5   NO.sub.2      H       CH.sub.3                                          L-5   NO.sub.2      H       OCH.sub.3                                         L-5   NO.sub.2      H       OCH.sub.2 CH.sub.3                                L-5   CO.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-5   CO.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-5   CO.sub.2 CH.sub.3                                                                           H       OCH.sub.2 CH.sub.3                                L-5   CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                              OCH.sub.3                                         L-5   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       CH.sub.3                                          L-5   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       OCH.sub.3                                         L-5   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       OCH.sub.2 CH.sub.3                                L-5   SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H       OCH.sub.3                                         L-5   SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H       OCH.sub.3                                         L-5   SCH.sub.3     H       OCH.sub.3                                         L-5   SOCH.sub.3    H       OCH.sub.3                                         L-5   SO.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-5   SO.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-5   SO.sub.2 CH.sub.3                                                                           H       OCH.sub.2 CH.sub.3                                L-6   CH.sub.3      H       CH.sub.3                                          L-6   CH.sub.3      H       OCH.sub.3                                         L-6   CH.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-6   CH.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-6   CH.sub.2 CH.sub.2 CH.sub.3                                                                  H       OCH.sub.3                                         L-6   F             H       OCH.sub.3                                         L-6   Cl            H       OCH.sub.3                                         L-6   Cl            H       CH.sub.3                                          L-6   Br            H       OCH.sub.3                                         L-6   NO.sub.2      H       CH.sub.3                                          L-6   NO.sub.2      H       OCH.sub.3                                         L-6   NO.sub.2      H       OCH.sub.2 CH.sub.3                                L-6   CO.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-6   CO.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-6   CO.sub.2 CH.sub.3                                                                           H       OCH.sub.2 CH.sub.3                                L-6   CO.sub.2 CH.sub.3                                                                           CH.sub.3                                                                              OCH.sub.3                                         L-6   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       CH.sub.3                                          L-6   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       OCH.sub.3                                         L-6   SO.sub.2 N(CH.sub.3).sub.2                                                                  H       OCH.sub.2 CH.sub.3                                L-6   SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H       OCH.sub.3                                         L-6   SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H       OCH.sub.3                                         L-6   SCH.sub.3     H       OCH.sub.3                                         L-6   SOCH.sub.3    H       OCH.sub.3                                         L-6   SO.sub.2 CH.sub.3                                                                           H       CH.sub.3                                          L-6   SO.sub.2 CH.sub.3                                                                           H       OCH.sub.3                                         L-6   SO.sub.2 CH.sub.3                                                                           H       OCH.sub.2 CH.sub.3                                ______________________________________                                    

                  TABLE 3c                                                        ______________________________________                                         ##STR52##                                                                    L        R.sub.5        R      m.p. (°C.)                              ______________________________________                                        L-4      CH.sub.3       H                                                     L-4      CH.sub.2 CH.sub.3                                                                            H                                                     L-4      CH.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-4      F              H                                                     L-4      Cl             H                                                     L-4      Br             H                                                     L-4      NO.sub.2       H                                                     L-4      CO.sub.2 CH.sub.3                                                                            H                                                     L-4      CO.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-4      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                          H                                                     L-4      SO.sub.2 N(CH.sub.3).sub.2                                                                   H                                                     L-4      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                          H                                                     L-4      SO.sub.2 N(OCH.sub.3)CH.sub.3                                                                H                                                     L-4      SCH.sub.3      H                                                     L-4      SOCH.sub.3     H                                                     L-4      SO.sub.2 CH.sub.3                                                                            H                                                     L-4      CO.sub.2 CH.sub.3                                                                            CH.sub.3                                              L-5      CH.sub.3       H                                                     L-5      CH.sub.2 CH.sub.3                                                                            H                                                     L-5      CH.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-5      F              H                                                     L-5      Cl             H                                                     L-5      Br             H                                                     L-5      NO.sub.2       H                                                     L-5      CO.sub.2 CH.sub.3                                                                            H                                                     L-5      CO.sub. 2 CH.sub.2 CH.sub.3                                                                  H                                                     L-5      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                          H                                                     L-5      SO.sub.2 N(CH.sub.3).sub.2                                                                   H                                                     L-5      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                          H                                                     L-5      SO.sub.2 N(OCH.sub.3)CH.sub.3                                                                H                                                     L-5      SCH.sub.3      H                                                     L-5      SOCH.sub.3     H                                                     L-5      SO.sub.2 CH.sub.3                                                                            H                                                     L-5      CO.sub.2 CH.sub.3                                                                            CH.sub.3                                              L-6      CH.sub.3       H                                                     L-6      CH.sub.2 CH.sub.3                                                                            H                                                     L-6      CH.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-6      F              H                                                     L-6      Cl             H                                                     L-6      Br             H                                                     L-6      NO.sub.2       H                                                     L-6      CO.sub.2 CH.sub.3                                                                            H                                                     L-6      CO.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-6      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                          H                                                     L-6      SO.sub.2 N(CH.sub.3).sub.2                                                                   H                                                     L-6      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                          H                                                     L-6      SO.sub.2 N(OCH.sub.3)CH.sub.3                                                                H                                                     L-6      SCH.sub.3      H                                                     L-6      SOCH.sub.3     H                                                     L-6      SO.sub.2 CH.sub.3                                                                            H                                                     L-6      CO.sub.2 CH.sub.3                                                                            CH.sub.3                                              ______________________________________                                    

                  TABLE 3d                                                        ______________________________________                                         ##STR53##                                                                    L        R.sub.5        R      m.p. (°C.)                              ______________________________________                                        L-4      CH.sub.3       H                                                     L-4      CH.sub.2 CH.sub.3                                                                            H                                                     L-4      CH.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-4      F              H                                                     L-4      Cl             H                                                     L-4      Br             H                                                     L-4      NO.sub.2       H                                                     L-4      CO.sub.2 CH.sub.3                                                                            H                                                     L-4      CO.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-4      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                          H                                                     L-4      SO.sub.2 N(CH.sub.3).sub.2                                                                   H                                                     L-4      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                          H                                                     L-4      SO.sub.2 N(OCH.sub.3)CH.sub.3                                                                H                                                     L-4      SCH.sub.3      H                                                     L-4      SOCH.sub.3     H                                                     L-4      SO.sub.2 CH.sub.3                                                                            H                                                     L-4      CO.sub.2 CH.sub.3                                                                            CH.sub.3                                              L-5      CH.sub.3       H                                                     L-5      CH.sub.2 CH.sub.3                                                                            H                                                     L-5      CH.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-5      F              H                                                     L-5      Cl             H                                                     L-5      Br             H                                                     L-5      NO.sub.2       H                                                     L-5      CO.sub.2 CH.sub.3                                                                            H                                                     L-5      CO.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-5      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                          H                                                     L-5      SO.sub.2 N(CH.sub.3).sub.2                                                                   H                                                     L-5      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                          H                                                     L-5      SO.sub.2 N(OCH.sub.3)CH.sub.3                                                                H                                                     L-5      SCH.sub.3      H                                                     L-5      SOCH.sub.3     H                                                     L-5      SO.sub.2 CH.sub.3                                                                            H                                                     L-5      CO.sub.2 CH.sub.3                                                                            CH.sub.3                                              L-6      CH.sub.3       H                                                     L-6      CH.sub.2 CH.sub.3                                                                            H                                                     L-6      CH.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-6      F              H                                                     L-6      Cl             H                                                     L-6      Br             H                                                     L-6      NO.sub.2       H                                                     L-6      CO.sub.2 CH.sub.3                                                                            H                                                     L-6      CO.sub.2 CH.sub.2 CH.sub.3                                                                   H                                                     L-6      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                          H                                                     L-6      SO.sub.2 N(CH.sub.3).sub.2                                                                   H                                                     L-6      SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                          H                                                     L-6      SO.sub.2 N(OCH.sub.3)CH.sub.3                                                                H                                                     L-6      SCH.sub.3      H                                                     L-6      SOCH.sub.3     H                                                     L-6      SO.sub.2 CH.sub.3                                                                            H                                                     L-6      CO.sub.2 CH.sub.3                                                                            CH.sub.3                                              ______________________________________                                    

                  TABLE 3e                                                        ______________________________________                                         ##STR54##                                                                                                                m.p.                              L    R.sub.5       R      X.sub.1  E   Z    (°C.)                      ______________________________________                                        L-4  CH.sub.3      H      OCH.sub.3                                                                              F   CH                                     L-4  CH.sub.3      H      OCH.sub.3                                                                              Cl  CH                                     L-4  CH.sub.3      H      OCH.sub.3                                                                              F   N                                      L-4  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   CH                                     L-4  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Cl  CH                                     L-4  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Br  CH                                     L-4  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   N                                      L-4  CH.sub.2 CH.sub.3                                                                           H      CH.sub.3 F   CH                                     L-4  CH.sub.2 CH.sub.2 CH.sub.3                                                                  H      OCH.sub.3                                                                              F   CH                                     L-4  CH.sub.2 CH.sub.2 CH.sub.3                                                                  H      CH.sub.3 F   CH                                     L-4  F             H      OCH.sub.3                                                                              F   CH                                     L-4  F             H      OCH.sub.3                                                                              Cl  CH                                     L-4  Cl            H      OCH.sub.3                                                                              F   CH                                     L-4  Cl            H      CH.sub.3 F   CH                                     L-4  Cl            H      OCH.sub.3                                                                              F   N                                      L-4  NO.sub.2      H      OCH.sub.3                                                                              F   CH                                     L-4  NO.sub.2      H      OCH.sub.3                                                                              Cl  CH                                     L-4  NO.sub.2      H      OCH.sub.3                                                                              F   N                                      L-4  NO.sub.2      H      CH.sub.3 Br  CH                                     L-4  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              F   CH                                     L-4  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              Cl  CH                                     L-4  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              Br  CH                                     L-4  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              F   N                                      L-4  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      CH.sub.3 F   CH                                     L-4  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.2 CH.sub.3                                                                     F   CH                                     L-4  SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                             OCH.sub.3                                                                              F   CH                                     L-4  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H      OCH.sub.3                                                                              F   CH                                     L-4  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H      OCH.sub.3                                                                              F   N                                      L-4  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              F   CH                                     L-4  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              Cl  CH                                     L-4  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              Br  CH                                     L-4  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      CH.sub.3 F   CH                                     L-4  SCH.sub.3     H      OCH.sub.3                                                                              F   CH                                     L-4  SCH.sub.3     H      OCH.sub.3                                                                              Cl  CH                                     L-4  SCH.sub.3     H      OCH.sub.3                                                                              Br  CH                                     L-4  SCH.sub.3     H      CH.sub.3 F   CH                                     L-4  SOCH.sub.3    H      OCH.sub.3                                                                              F   CH                                     L-4  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   CH                                     L-4  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Cl  CH                                     L-4  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Br  CH                                     L-4  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   N                                      L-4  SO.sub.2 CH.sub.3                                                                           H      CH.sub.3 F   CH                                     L-4  SO.sub.2 CH.sub.3                                                                           H      CH.sub.3 Cl  CH                                     L-5  CH.sub.3      H      OCH.sub.3                                                                              F   CH                                     L-5  CH.sub.3      H      OCH.sub.3                                                                              Cl  CH                                     L-5  CH.sub.3      H      OCH.sub.3                                                                              F   N                                      L-5  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   CH                                     L-5  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Cl  CH                                     L-5  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Br  CH                                     L-5  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   N                                      L-5  CH.sub.2 CH.sub.3                                                                           H      CH.sub.3 F   CH                                     L-5  CH.sub.2 CH.sub.2 CH.sub.3                                                                  H      OCH.sub.3                                                                              F   CH                                     L-5  CH.sub.2 CH.sub.2 CH.sub.3                                                                  H      CH.sub.3 F   CH                                     L-5  F             H      OCH.sub.3                                                                              F   CH                                     L-5  F             H      OCH.sub.3                                                                              Cl  CH                                     L-5  Cl            H      OCH.sub.3                                                                              F   CH                                     L-5  Cl            H      CH.sub.3 F   CH                                     L-5  Cl            H      OCH.sub.3                                                                              F   N                                      L-5  NO.sub.2      H      OCH.sub.3                                                                              F   CH                                     L-5  NO.sub.2      H      OCH.sub.3                                                                              Cl  CH                                     L-5  NO.sub.2      H      OCH.sub.3                                                                              F   N                                      L-5  NO.sub.2      H      CH.sub.3 Br  CH                                     L-5  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              F   CH                                     L-5  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              Cl  CH                                     L-5  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              Br  CH                                     L-5  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              F   N                                      L-5  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      CH.sub.3 F   CH                                     L-5  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.2 CH.sub.3                                                                     F   CH                                     L-5  SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                             OCH.sub.3                                                                              F   CH                                     L-5  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H      OCH.sub.3                                                                              F   CH                                     L-5  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H      OCH.sub.3                                                                              F   N                                      L-5  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              F   CH                                     L-5  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              Cl  CH                                     L-5  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              Br  CH                                     L-5  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      CH.sub.3 F   CH                                     L-5  SCH.sub.3     H      OCH.sub.3                                                                              F   CH                                     L-5  SCH.sub.3     H      OCH.sub.3                                                                              Cl  CH                                     L-5  SCH.sub.3     H      OCH.sub.3                                                                              Br  CH                                     L-5  SCH.sub.3     H      CH.sub.3 F   CH                                     L-5  SOCH.sub.3    H      OCH.sub.3                                                                              F   CH                                     L-5  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   CH                                     L-5  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Cl  CH                                     L-5  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Br  CH                                     L-5  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   N                                      L-5  SO.sub.2 CH.sub.3                                                                           H      CH.sub.3 F   CH                                     L-5  SO.sub.2 CH.sub.3                                                                           H      CH.sub.3 Cl  CH                                     L-6  CH.sub.3      H      OCH.sub.3                                                                              F   CH                                     L-6  CH.sub.3      H      OCH.sub.3                                                                              Cl  CH                                     L-6  CH.sub.3      H      OCH.sub.3                                                                              F   N                                      L-6  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   CH                                     L-6  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Cl  CH                                     L-6  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Br  CH                                     L-6  CH.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   N                                      L-6  CH.sub.2 CH.sub.3                                                                           H      CH.sub.3 F   CH                                     L-6  CH.sub.2 CH.sub.2 CH.sub.3                                                                  H      OCH.sub.3                                                                              F   CH                                     L-6  CH.sub.2 CH.sub.2 CH.sub.3                                                                  H      CH.sub.3 F   CH                                     L-6  F             H      OCH.sub.3                                                                              F   CH                                     L-6  F             H      OCH.sub.3                                                                              Cl  CH                                     L-6  Cl            H      OCH.sub.3                                                                              F   CH                                     L-6  Cl            H      CH.sub.3 F   CH                                     L-6  Cl            H      OCH.sub.3                                                                              F   N                                      L-6  NO.sub.2      H      OCH.sub.3                                                                              F   CH                                     L-6  NO.sub.2      H      OCH.sub.3                                                                              Cl  CH                                     L-6  NO.sub.2      H      OCH.sub.3                                                                              F   N                                      L-6  NO.sub.2      H      CH.sub.3 Br  CH                                     L-6  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              F   CH                                     L-6  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              Cl  CH                                     L-6  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              Br  CH                                     L-6  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.3                                                                              F   N                                      L-6  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      CH.sub.3 F   CH                                     L-6  SO.sub.2 N(CH.sub.3).sub.2                                                                  H      OCH.sub.2 CH.sub.3                                                                     F   CH                                     L-6  SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                             OCH.sub.3                                                                              F   CH                                     L-6  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H      OCH.sub. 3                                                                             F   CH                                     L-6  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                         H      OCH.sub.3                                                                              F   N                                      L-6  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              F   CH                                     L-6  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              Cl  CH                                     L-6  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      OCH.sub.3                                                                              Br  CH                                     L-6  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                               H      CH.sub.3 F   CH                                     L-6  SCH.sub.3     H      OCH.sub.3                                                                              F   CH                                     L-6  SCH.sub.3     H      OCH.sub.3                                                                              Cl  CH                                     L-6  SCH.sub.3     H      OCH.sub.3                                                                              Br  CH                                     L-6  SCH.sub.3     H      CH.sub.3 F   CH                                     L-6  SOCH.sub.3    H      OCH.sub.3                                                                              F   CH                                     L-6  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   CH                                     L-6  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Cl  CH                                     L-6  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              Br  CH                                     L-6  SO.sub.2 CH.sub.3                                                                           H      OCH.sub.3                                                                              F   N                                      L-6  SO.sub.2 CH.sub.3                                                                           H      CH.sub.3 F   CH                                     L-6  SO.sub.2 CH.sub.3                                                                           H      CH.sub.3 Cl  CH                                     ______________________________________                                    

                                      TABLE 3f                                    __________________________________________________________________________     ##STR55##                                                                    L  R.sub.5 R  X   Z  G           m.p. (°C.)                            __________________________________________________________________________    L-4                                                                              CO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                                 L-4                                                                              CH.sub.3                                                                              H  OCH.sub.3                                                                         N  CH(OCH.sub.3).sub.2                                      L-4                                                                              Br      H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                      L-4                                                                              CO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                      L-5                                                                              CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          CH CH(OCH.sub.2 CH.sub.2 O)                                                                  146-148                                      L-5                                                                              CO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                         CH C.sub.6 H.sub.5                                          L-5                                                                              SO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                         OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                      L-5                                                                              CH.sub.3                                                                              H  OCH.sub.3                                                                         N  CH(OCH.sub.3).sub.2                                      L-5                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                         CH CH(OCH.sub.3).sub.2                                      L-5                                                                              Cl      H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                                 L-6                                                                              CO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                         CH CH(OCH.sub.2 CH.sub.2 O)                                 L-6                                                                              CO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                         CH C.sub.6 H.sub.5                                          L-6                                                                              SCH.sub.3                                                                             H  CH.sub.3                                                                          CH CH(OCH.sub.3).sub.2                                      __________________________________________________________________________

                  TABLE 4a                                                        ______________________________________                                         ##STR56##                                                                                                                m.p.                              R.sub.6   R      X       Y     T       Z    (°C.)                      ______________________________________                                        Cl        H      OCH.sub.3                                                                             H     SPh     CH                                     NO.sub.2  H      OCH.sub.3                                                                             H     SPh     CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SeCH.sub.3                                                                            CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SePh    CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SPh     CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SO.sub.2 Ph                                                                           CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     OPh     CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SeCH.sub.3                                                                            N                                      CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SePh    N                                      CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SPh     N                                      CO.sub.2 CH.sub.2 CH.sub.3                                                              H      OCH.sub.3                                                                             H     SeCH.sub.3                                                                            CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                              H      OCH.sub.3                                                                             H     SPh     CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      OCH.sub.3                                                                             H     SeCH.sub.3                                                                            CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      OCH.sub.3                                                                             H     SePh    CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      OCH.sub.3                                                                             H     SPh     CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      OCH.sub.3                                                                             H     SO.sub.2 Ph                                                                           CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      OCH.sub.3                                                                             H     OPh     CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      OCH.sub.3                                                                             H     SPh     N                                      SO.sub.2 CH.sub.2 CH.sub.3                                                              H      OCH.sub.3                                                                             H     SPh     CH                                     SO.sub.2 CH.sub.2 CH.sub.3                                                              H      OCH.sub.3                                                                             H     SPh     N                                      OCH.sub.3 H      OCH.sub.3                                                                             H     SeCH.sub.3                                                                            CH                                     OCH.sub.3 H      OCH.sub.3                                                                             H     SePh    CH                                     OCH.sub.2 CH.sub.3                                                                      H      OCH.sub.3                                                                             H     SeCH.sub.3                                                                            CH                                     SO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SeCH.sub.3                                                                            CH                                     SO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     SePh    CH                                     SO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             H     SPh     CH                                     SO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             H     SO.sub.2 Ph                                                                           CH                                     Cl        CH.sub.3                                                                             CH.sub.3                                                                              H     SPh     CH                                     NO.sub.2  H      CH.sub.3                                                                              H     SPh     CH                                     CO.sub.2 CH.sub.3                                                                       H      CH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                     CO.sub.2 CH.sub.3                                                                       H      CH.sub.3                                                                              H     SePh    CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             SPh   SPh     CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             SeCH.sub.3                                                                          SO.sub.2 Ph                                                                           CH                                     CO.sub.2 CH.sub.3                                                                       H      CH.sub.3                                                                              H     OPh     CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             SeCH.sub.3                                                                          SeCH.sub.3                                                                            N                                      CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             SePh  SePh    N                                      CO.sub.2 CH.sub.3                                                                       H      CH.sub.3                                                                              H     SPh     N                                      CO.sub.2 CH.sub.2 CH.sub.3                                                              H      OCH.sub.3                                                                             SeCH.sub.3                                                                          SeCH.sub.3                                                                            CH                                     CO.sub.2 CH.sub.2 CH.sub.3                                                              H      CH.sub.3                                                                              H     SPh     CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      CH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              CH.sub.3                                                                             CH.sub.3                                                                              H     SePh    CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              CH.sub.3                                                                             CH.sub.3                                                                              H     SPh     CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      OCH.sub.3                                                                             SPh   SO.sub.2 Ph                                                                           CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      CH.sub.3                                                                              H     OPh     CH                                     SO.sub.2 N(CH.sub.3).sub.2                                                              H      CH.sub.3                                                                              H     SPh     N                                      SO.sub.2 CH.sub.2 CH.sub.3                                                              H      CH.sub.3                                                                              H     SPh     CH                                     SO.sub.2 CH.sub.2 CH.sub.3                                                              H      OCH.sub.3                                                                             SPh   SPh     N                                      OCH.sub.3 H      OCH.sub.3                                                                             SeCH.sub.3                                                                          SeCH.sub.3                                                                            CH                                     CH.sub.3  H      CH.sub.3                                                                              H     SePh    CH                                     CH.sub.2 CH.sub.3                                                                       H      CH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                     SO.sub.2 CH.sub.3                                                                       H      CH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                     SO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             SePh  SePh    CH                                     SO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             SPh   SPh     CH                                     SO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                              H     SO.sub.2 Ph                                                                           CH                                     CO.sub.2 CH.sub.3                                                                       H      OCH.sub.3                                                                             H     OSi(CH.sub.3).sub.3                                                                   CH                                     SO.sub.2 CH.sub.3                                                                       H      CH.sub.3                                                                              H     CH.sub.2 OH                                                                           N                                      ______________________________________                                    

                  TABLE 4b                                                        ______________________________________                                         ##STR57##                                                                    R.sub.6      R        X.sub.1   m.p. (°C.)                             ______________________________________                                        Cl           H        OCH.sub.3                                               NO.sub.2     H        OCH.sub.3                                               CO.sub.2 CH.sub.3                                                                          H        CH.sub.3                                                CO.sub.2 CH.sub.3                                                                          H        OCH.sub.3                                               CO.sub.2 CH.sub.3                                                                          H        OCH.sub.2 CH.sub.3                                      CO.sub.2 CH.sub.2 CH.sub.3                                                                 H        CH.sub.3                                                CO.sub.2 CH.sub.2 CH.sub.3                                                                 H        OCH.sub.3                                               CO.sub.2 CH.sub.2 CH.sub.3                                                                 H        OCH.sub.2 CH.sub.3                                      SO.sub.2 N(CH.sub.3).sub.2                                                                 H        OCH.sub.3                                               SO.sub.2 N(CH.sub.3).sub.2                                                                 H        CH.sub.3                                                OSO.sub.2 CH.sub.3                                                                         H        OCH.sub.3                                               SO.sub.2 CH.sub.3                                                                          H        OCH.sub.3                                               SO.sub.2 CH.sub.2 CH.sub.3                                                                 H        OCH.sub.3                                               OCH.sub.3    CH.sub.3 OCH.sub.3                                               OCH.sub.2 CH.sub.3                                                                         CH.sub.3 OCH.sub.3                                               ______________________________________                                    

                  TABLE 4c                                                        ______________________________________                                         ##STR58##                                                                    R.sub.6         R      m.p. (°C.)                                      ______________________________________                                        Cl              H                                                             NO.sub.2        H                                                             CO.sub.2 CH.sub.3                                                                             H                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                    H                                                             SO.sub.2 N(CH.sub.3).sub.2                                                                    H                                                             OSO.sub.2 CH.sub.3                                                                            H                                                             SO.sub.2 CH.sub.3                                                                             H                                                             SO.sub.2 CH.sub.2 CH.sub.3                                                                    H                                                             OCH.sub.3       CH.sub.3                                                      OCH.sub.2 CH.sub.3                                                                            CH.sub.3                                                      ______________________________________                                    

                  TABLE 4d                                                        ______________________________________                                         ##STR59##                                                                    R.sub.6         R      m.p. (°C.)                                      ______________________________________                                        Cl              H                                                             NO.sub.2        H                                                             CO.sub.2 CH.sub.3                                                                             H                                                             CO.sub.2 CH.sub.2 CH.sub.3                                                                    H                                                             SO.sub.2 N(CH.sub.3).sub.2                                                                    H                                                             OSO.sub.2 CH.sub.3                                                                            H                                                             SO.sub.2 CH.sub.3                                                                             H                                                             SO.sub.2 CH.sub.2 CH.sub.3                                                                    H                                                             OCH.sub.3       H                                                             OCH.sub.2 CH.sub.3                                                                            CH.sub.3                                                      ______________________________________                                    

                  TABLE 4e                                                        ______________________________________                                         ##STR60##                                                                    R.sub.6   R       X.sub.1    E    Z    m.p. (°C.)                      ______________________________________                                        Cl        H       OCH.sub.3  F    CH                                          NO.sub.2  H       CH.sub.3   F    CH                                          NO.sub.2  H       OCH.sub.3  F    CH                                          NO.sub.2  H       OCH.sub.3  Cl   CH                                          CO.sub.2 CH.sub.3                                                                       H       OCH.sub.3  F    CH                                          CO.sub.2 CH.sub.3                                                                       H       CH.sub.3   Cl   CH                                          CO.sub.2 CH.sub.3                                                                       H       OCH.sub.3  Br   CH                                          CO.sub.2 CH.sub.3                                                                       H       OCH.sub.3  F    N                                           CO.sub.2 CH.sub.3                                                                       H       CH.sub.3   F    CH                                          CO.sub.3 CH.sub.3                                                                       H       OCH.sub.2 CH.sub.3                                                                       F    CH                                          CO.sub.2 CH.sub.2 CH.sub.3                                                              H       OCH.sub.3  F    CH                                          SO.sub.2 N(CH.sub.3).sub.2                                                              CH.sub.3                                                                              OCH.sub.3  F    CH                                          SO.sub.2 N(CH.sub.3).sub.2                                                              CH.sub.3                                                                              OCH.sub. 3 F    N                                           SO.sub.2 N(CH.sub.3).sub.2                                                              CH.sub.3                                                                              OCH.sub.3  Cl   CH                                          SO.sub.2 N(CH.sub.3).sub.2                                                              CH.sub.3                                                                              CH.sub.3   Br   CH                                          OSO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                              OCH.sub.3  F    CH                                          SO.sub.2 CH.sub.3                                                                       H       OCH.sub.3  F    CH                                          SO.sub.2 CH.sub.3                                                                       H       CH.sub.3   F    CH                                          SO.sub.2 CH.sub.2 CH.sub.3                                                              H       OCH.sub.3  F    CH                                          OCH.sub.3 H       OCH.sub.3  F    CH                                          OCH.sub.2 CH.sub.3                                                                      H       OCH.sub.3  F    CH                                          OCH.sub.2 CH.sub.3                                                                      H       OCH.sub.3  Br   CH                                          OCH.sub.2 CH.sub.3                                                                      H       OCH.sub.3  F    N                                           ______________________________________                                    

                  TABLE 4f                                                        ______________________________________                                         ##STR61##                                                                                                              m.p.                                R.sub.6  R     X       Z    G             (°C.)                        ______________________________________                                        Cl       H     OCH.sub.3                                                                             CH   CH(OCH.sub.2 CH.sub.2 O)                          NO.sub.2 H     OCH.sub.3                                                                             N    CH(OCH.sub.2 CH.sub.2 O)                          CO.sub.2 CH.sub.3                                                                      H     OCH.sub.3                                                                             CH   CH(OCH.sub.2 CH.sub.2 O)                          CO.sub.2 CH.sub.3                                                                      H     CH.sub.3                                                                              CH   CH(OCH.sub.3).sub.2                               SO.sub.2 CH.sub.3                                                                      H     OCH.sub.3                                                                             CH   CH(OCH.sub.2 CH.sub.2 O)                          OCH.sub.3                                                                              H     OCH.sub.3                                                                             CH   C.sub.6 H.sub.5                                   OSO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                             CH   CH(OCH.sub.2 CH.sub.2 O)                          ______________________________________                                    

                                      TABLE 5a                                    __________________________________________________________________________     ##STR62##                                                                    R.sub.7                                                                             R.sub.8                                                                           R.sub.9                                                                           R   Q.sub.1                                                                           X    T    Y      Z   m  m.p. (°C.)               __________________________________________________________________________    CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SePh   CH  0                                  CH.sub. 3                                                                           H   H   H   O   OCH.sub.3                                                                          H    SPh    CH  0                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  0                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SPh    N   0                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           H    SePh   CH  0                                  CH.sub.3                                                                            CH.sub.3                                                                          H   H   O   CH.sub.3                                                                           H    SPh    CH  0                                  CH.sub.3                                                                            H   H   CH.sub.3                                                                          O   CH.sub.3                                                                           SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           SeCH.sub.3                                                                         SPh    CH  0                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           SPh  SPh    CH  0                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           H    OPh    CH  0                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    OPh    CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SePh   CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SPh    CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SPh    N   0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           N   0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  0                                  CH.sub. 2 CH.sub.3                                                                  H   H   H   O   CH.sub.3                                                                           H    SePh   CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   CH.sub.3                                                                           H    SPh    CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          SPh  SPh    CH  0                                  CH.sub.3                                                                            H   CH.sub.3                                                                          H   O   OCH.sub.3                                                                          H    SePh   CH  0                                  CH.sub.3                                                                            H   CH.sub.3                                                                          H   O   OCH.sub.3                                                                          H    SPh    CH  0                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SePh   CH  1                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SPh    CH  1                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  1                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    SPh    N   1                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           H    SePh   CH  1                                  CH.sub.3                                                                            CH.sub.3                                                                          H   H   O   CH.sub.3                                                                           H    SPh    CH  1                                  CH.sub.3                                                                            H   H   CH.sub.3                                                                          O   CH.sub.3                                                                           SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           SeCH.sub.3                                                                         SPh    CH  1                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           SPh  SPh    CH  1                                  CH.sub.3                                                                            H   H   H   O   CH.sub.3                                                                           H    OPh    CH  1                                  CH.sub.3                                                                            H   H   H   O   OCH.sub.3                                                                          H    OPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SePh   CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SPh    N   1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           N   1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   CH.sub.3                                                                           H    SePh   CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   CH.sub.3                                                                           H    SPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   O   OCH.sub.3                                                                          SPh  SPh    CH  1                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SePh   CH  0                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SPh    CH  0                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  0                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SPh    N   0                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           H    SePh   CH  0                                  CH.sub.3                                                                            CH.sub.3                                                                          H   H   S   CH.sub.3                                                                           H    SPh    CH  0                                  CH.sub.3                                                                            H   H   CH.sub.3                                                                          S   CH.sub.3                                                                           SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           SeCH.sub.3                                                                         SPh    CH  0                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           SPh  SPh    CH  0                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           H    OPh    CH  0                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    OPh    CH  0                                  CH.sub. 2 CH.sub.3                                                                  H   H   H   S   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SePh   CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SPh    CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SPh    N   0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           N   0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   CH.sub.3                                                                           H    SePh   CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   CH.sub.3                                                                           H    SPh    CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          SPh  SPh    CH  0                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SePh   CH  1                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SPh    CH  1                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  1                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    SPh    N   1                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           H    SePh   CH  1                                  CH.sub.3                                                                            CH.sub.3                                                                          H   H   S   CH.sub.3                                                                           H    SPh    CH  1                                  CH.sub.3                                                                            H   H   CH.sub.3                                                                          S   CH.sub.3                                                                           SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           SeCH.sub.3                                                                         SPh    CH  1                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           SPh  SPh    CH  1                                  CH.sub.3                                                                            H   H   H   S   CH.sub.3                                                                           H    OPh    CH  1                                  CH.sub.3                                                                            H   H   H   S   OCH.sub.3                                                                          H    OPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SePh   CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SPh    N   1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          H    SeCH.sub.3                                                                           N   1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   CH.sub.3                                                                           H    SePh   CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   CH.sub.3                                                                           H    SPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   S   OCH.sub.3                                                                          SPh  SPh    CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SePh   CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SPh    CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SPh    N   0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SePh   CH  0                                  CH.sub.3                                                                            CH.sub.3                                                                          H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SPh    CH  0                                  CH.sub.3                                                                            H   H   CH.sub.3                                                                          SO.sub.2                                                                          CH.sub.3                                                                           SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           SeCH.sub.3                                                                         SPh    CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           SPh  SPh    CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    OPh    CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    OPh    CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SePh   CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SPh    CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SPh    N   0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SeCH.sub.3                                                                           N   0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SeCH.sub. 3                                                                          CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SePh   CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SPh    CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  0                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          SPh  SPh    CH  0                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SePh   CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SPh    CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SPh    N   1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          SeCH.sub.3                                                                         SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SePh   CH  1                                  CH.sub.3                                                                            CH.sub.3                                                                          H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SPh    CH  1                                  CH.sub.3                                                                            H   H   CH.sub.3                                                                          SO.sub.3                                                                          CH.sub.3                                                                           SeCH.sub.3                                                                         SeCH.sub. 3                                                                          CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           SeCH.sub.3                                                                         SPh    CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           SPh  SPh    CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    OPh    CH  1                                  CH.sub.3                                                                            H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    OPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SeCH.sub.3                                                                           CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SePh   CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SO.sub.2 Ph                                                                          CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SPh    N   1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    SeCH.sub.3                                                                           N   1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SeCH.sub.3                                                                           CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SePh   CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          CH.sub.3                                                                           H    SPh    CH  1                                  CH.sub.2 CH.sub.3                                                                   H   H   H   SO.sub.2                                                                          OCH.sub.3                                                                          H    OSi(CH.sub.3).sub.3                                                                  CH  0                                  __________________________________________________________________________

                  TABLE 5b                                                        ______________________________________                                         ##STR63##                                                                    R.sub.7                                                                              R.sub.8                                                                              R.sub.9                                                                              m   Q.sub.1                                                                            R    X.sub.1 m.p. (°C.)                  ______________________________________                                        CH.sub.3                                                                             H      H      0   S    H    OCH.sub.3                                  CH.sub.3                                                                             H      H      0   S    H    CH.sub.3                                   CH.sub.3                                                                             H      H      0   S    H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      H      0   S    H    OCH.sub.3                                  CH.sub.2 CH.sub.3                                                                    H      H      0   S    H    CH.sub.3                                   CH.sub.2 CH.sub.3                                                                    H      H      0   S    H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      0   S    H    OCH.sub.3                                  CH.sub.3                                                                             CH.sub.3                                                                             H      0   S    H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      0   S    H    CH.sub.3                                   CH.sub.3                                                                             H      CH.sub.3                                                                             0   S    H    CH.sub.3                                   CH.sub.3                                                                             H      CH.sub.3                                                                             0   S    H    OCH.sub.3                                  CH.sub.3                                                                             H      CH.sub.3                                                                             0   S    H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      CH.sub.3                                                                             0   S    H    OCH.sub.3                                  CH.sub.3                                                                             H      H      1   S    H    OCH.sub.3                                  CH.sub.3                                                                             H      H      1   S    H    CH.sub.3                                   CH.sub.3                                                                             H      H      1   S    H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      H      1   S    H    OCH.sub.3                                  CH.sub.2 CH.sub.3                                                                    H      H      1   S    H    CH.sub.3                                   CH.sub.2 CH.sub.3                                                                    H      H      1   S    H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      1   S    H    OCH.sub.3                                  CH.sub.3                                                                             CH.sub.3                                                                             H      1   S    H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             H      H      1   S    CH.sub.3                                                                           OCH.sub.3                                  CH.sub.3                                                                             H      H      0   O    H    OCH.sub.3                                  CH.sub.3                                                                             H      H      0   O    H    CH.sub.3                                   CH.sub.3                                                                             H      H      0   O    H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      H      0   O    H    OCH.sub.3                                  CH.sub.2 CH.sub.3                                                                    H      H      0   O    H    CH.sub.3                                   CH.sub.2 CH.sub.3                                                                    H      H      0   O    H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      0   O    H    OCH.sub.3                                  CH.sub.3                                                                             CH.sub.3                                                                             H      0   O    H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      0   O    H    CH.sub.3                                   CH.sub.3                                                                             H      CH.sub.3                                                                             0   O    H    CH.sub.3                                   CH.sub.3                                                                             H      CH.sub.3                                                                             0   O    H    OCH.sub.3                                  CH.sub.3                                                                             H      CH.sub.3                                                                             0   O    H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      CH.sub.3                                                                             0   O    H    OCH.sub.3                                  CH.sub.3                                                                             H      H      1   O    H    OCH.sub.3                                  CH.sub.3                                                                             H      H      1   O    H    CH.sub.3                                   CH.sub.3                                                                             H      H      1   O    H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      H      1   O    H    OCH.sub.3                                  CH.sub.2 CH.sub.3                                                                    H      H      1   O    H    CH.sub.3                                   CH.sub.2 CH.sub.3                                                                    H      H      1   O    H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      1   O    H    OCH.sub.3                                  CH.sub.3                                                                             CH.sub.3                                                                             H      1   O    H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             H      H      1   O    CH.sub.3                                                                           OCH.sub.3                                  CH.sub.3                                                                             H      H      0   SO.sub.2                                                                           H    OCH.sub.3                                  CH.sub.3                                                                             H      H      0   SO.sub.2                                                                           H    CH.sub.3                                   CH.sub.3                                                                             H      H      0   SO.sub.2                                                                           H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      H      0   SO.sub.2                                                                           H    OCH.sub.3                                  CH.sub.2 CH.sub.3                                                                    H      H      0   SO.sub.2                                                                           H    CH.sub.3                                   CH.sub.2 CH.sub.3                                                                    H      H      0   SO.sub.2                                                                           H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      0   SO.sub.2                                                                           H    OCH.sub.3                                  CH.sub.3                                                                             CH.sub.3                                                                             H      0   SO.sub.2                                                                           H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      0   SO.sub.2                                                                           H    CH.sub.3                                   CH.sub.3                                                                             H      CH.sub.3                                                                             0   SO.sub.2                                                                           H    CH.sub.3                                   CH.sub.3                                                                             H      CH.sub.3                                                                             0   SO.sub.2                                                                           H    OCH.sub.3                                  CH.sub.3                                                                             H      CH.sub.3                                                                             0   SO.sub.2                                                                           H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      CH.sub.3                                                                             0   SO.sub.2                                                                           H    OCH.sub.3                                  CH.sub.3                                                                             H      H      1   SO.sub.2                                                                           H    OCH.sub.3                                  CH.sub.3                                                                             H      H      1   SO.sub.2                                                                           H    CH.sub.3                                   CH.sub.3                                                                             H      H      1   SO.sub.2                                                                           H    OCH.sub.2 CH.sub.3                         CH.sub.2 CH.sub.3                                                                    H      H      1   SO.sub.2                                                                           H    OCH.sub.3                                  CH.sub.2 CH.sub.3                                                                    H      H      1   SO.sub.2                                                                           H    CH.sub. 3                                  CH.sub.2 CH.sub.3                                                                    H      H      1   SO.sub.2                                                                           H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             CH.sub.3                                                                             H      1   SO.sub.2                                                                           H    OCH.sub.3                                  CH.sub.3                                                                             CH.sub.3                                                                             H      1   SO.sub.2                                                                           H    OCH.sub.2 CH.sub.3                         CH.sub.3                                                                             H      H      1   SO.sub.2                                                                           CH.sub.3                                                                           OCH.sub.3                                  ______________________________________                                    

                  TABLE 5c                                                        ______________________________________                                         ##STR64##                                                                    R.sub.7 R.sub.8 R.sub.9 Q.sub.1                                                                             R    m     m.p. (°C.)                    ______________________________________                                        CH.sub.3                                                                              H       H       O     H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              H       O     H    0                                          CH.sub.3                                                                              H       CH.sub.3                                                                              O     H    0                                          CH.sub.2 CH.sub.3                                                                     H       H       O     H    0                                          CH.sub.2 CH.sub.3                                                                     H       CH.sub.3                                                                              O     H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              CH.sub.3                                                                              O     H    0                                          CH.sub.3                                                                              H       H       O     CH.sub.3                                                                           0                                          CH.sub.3                                                                              H       H       O     H    1                                          CH.sub.3                                                                              CH.sub.3                                                                              H       O     H    1                                          CH.sub.2 CH.sub.3                                                                     H       H       O     H    1                                          CH.sub.3                                                                              H       H       S     H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              H       S     H    0                                          CH.sub.3                                                                              H       CH.sub.3                                                                              S     H    0                                          CH.sub.2 CH.sub.3                                                                     H       H       S     H    0                                          CH.sub.2 CH.sub.3                                                                     H       CH.sub.3                                                                              S     H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              CH.sub.3                                                                              S     H    0                                          CH.sub.3                                                                              H       H       S     CH.sub.3                                                                           0                                          CH.sub.3                                                                              H       H       S     H    1                                          CH.sub.3                                                                              CH.sub.3                                                                              H       S     H    1                                          CH.sub.2 CH.sub.3                                                                     H       H       S     H    1                                          CH.sub.3                                                                              H       H       SO.sub.2                                                                            H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              H       SO.sub.2                                                                            H    0                                          CH.sub.3                                                                              H       CH.sub.3                                                                              SO.sub.2                                                                            H    0                                          CH.sub.2 CH.sub.3                                                                     H       H       SO.sub.2                                                                            H    0                                          CH.sub.2 CH.sub.3                                                                     H       CH.sub.3                                                                              SO.sub.2                                                                            H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              CH.sub.3                                                                              SO.sub.2                                                                            H    0                                          CH.sub.3                                                                              H       H       SO.sub.2                                                                            CH.sub.3                                                                           0                                          CH.sub.3                                                                              H       H       SO.sub.2                                                                            H    1                                          CH.sub.3                                                                              CH.sub.3                                                                              H       SO.sub.2                                                                            H    1                                          CH.sub.2 CH.sub.3                                                                     H       H       SO.sub.2                                                                            H    1                                          ______________________________________                                    

                  TABLE 5d                                                        ______________________________________                                         ##STR65##                                                                    R.sub.7 R.sub.8 R.sub.9 Q.sub.1                                                                             R    m     m.p. (°C.)                    ______________________________________                                        CH.sub.3                                                                              H       H       O     H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              H       O     H    0                                          CH.sub.3                                                                              H       CH.sub.3                                                                              O     H    0                                          CH.sub.2 CH.sub.3                                                                     H       H       O     H    0                                          CH.sub.2 CH.sub.3                                                                     H       CH.sub.3                                                                              O     H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              CH.sub.3                                                                              O     H    0                                          CH.sub.3                                                                              H       H       O     CH.sub.3                                                                           0                                          CH.sub.3                                                                              H       H       O     H    1                                          CH.sub.3                                                                              CH.sub.3                                                                              H       O     H    1                                          CH.sub.2 CH.sub.3                                                                     H       H       O     H    1                                          CH.sub.3                                                                              H       H       S     H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              H       S     H    0                                          CH.sub.3                                                                              H       CH.sub.3                                                                              S     H    0                                          CH.sub.2 CH.sub.3                                                                     H       H       S     H    0                                          CH.sub.2 CH.sub.3                                                                     H       CH.sub.3                                                                              S     H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              CH.sub.3                                                                              S     H    0                                          CH.sub.3                                                                              H       H       S     CH.sub.3                                                                           0                                          CH.sub.3                                                                              H       H       S     H    1                                          CH.sub.3                                                                              CH.sub.3                                                                              H       S     H    1                                          CH.sub.2 CH.sub.3                                                                     H       H       S     H    1                                          CH.sub.3                                                                              H       H       SO.sub.2                                                                            H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              H       SO.sub.2                                                                            H    0                                          CH.sub.3                                                                              H       CH.sub.3                                                                              SO.sub.2                                                                            H    0                                          CH.sub.2 CH.sub.3                                                                     H       H       SO.sub.2                                                                            H    0                                          CH.sub.2 CH.sub.3                                                                     H       CH.sub.3                                                                              SO.sub.2                                                                            H    0                                          CH.sub.3                                                                              CH.sub.3                                                                              CH.sub.3                                                                              SO.sub.2                                                                            H    0                                          CH.sub.3                                                                              H       H       SO.sub.2                                                                            CH.sub.3                                                                           0                                          CH.sub.3                                                                              H       H       SO.sub.2                                                                            H    1                                          CH.sub.3                                                                              CH.sub.3                                                                              H       SO.sub.2                                                                            H    1                                          CH.sub.2 CH.sub.3                                                                     H       H       SO.sub.2                                                                            H    1                                          ______________________________________                                    

                                      TABLE 5e                                    __________________________________________________________________________     ##STR66##                                                                    Q.sub.1                                                                           m  R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                           R  X    Z   G           m.p. (°C.)                  __________________________________________________________________________    O   0  H   H   H   H  OCH.sub.3                                                                          CH  CH(OCH.sub.2 CH.sub.2 O)                       O   0  CH.sub.3                                                                          H   H   H  OCH.sub.3                                                                          N   CH(OCH.sub.3).sub.2                            S   1  H   H   H   H  OCH.sub.3                                                                          CH  CH(OCH.sub.3).sub.2                            S   0  CH.sub.3                                                                          H   H   H  OCH.sub.3                                                                          CH  C.sub.6 H.sub.5                                SO.sub.2                                                                          0  H   H   H   H  OCH.sub.3                                                                          CH  CH( OCH.sub.2 CH.sub.2 O)                      SO.sub.2                                                                          0  CH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3                                                                          H  OCH.sub.3                                                                          CH  CH(OCH.sub.2 CH.sub.2 O)                       SO.sub.2                                                                          1  H   H   H   H  CH.sub.3                                                                           CH  CH(OCH.sub.2 CH.sub.2 O)                       S   0  H   H   H   H  OCH.sub.3                                                                          CH  CH(OCH.sub.2 CH.sub.2 O)                       O   0  H   H   H   H  OCH.sub.3                                                                          CH  CH(OCH.sub.3).sub.2                            S   0  H   H   H   H  OCH.sub.3                                                                          CH  C.sub.6 H.sub.5                                SO.sub.2                                                                          1  H   H   H   H  OCH.sub.3                                                                          CH  CH(OCH.sub.3).sub.2                            __________________________________________________________________________

                  TABLE 6a                                                        ______________________________________                                         ##STR67##                                                                                                                   m.p.                           R.sub.10                                                                           R.sub.11                                                                             Q.sub.2                                                                             R    X     T     Y         Z (°C.)                   ______________________________________                                        H    H      O     H    OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               H    H      O     H    OCH.sub.3                                                                           H     SePh      CH                               H    H      O     H    OCH.sub.3                                                                           H     SPh       CH                               CH.sub.3                                                                           H      O     H    OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           H      O     H    OCH.sub.3                                                                           H     SePh      CH                               CH.sub.3                                                                           H      O     H    OCH.sub.3                                                                           H     SPh       CH                               CH.sub.3                                                                           H      O     H    OCH.sub.3                                                                           H     SO.sub.2 Ph                                                                             CH                               CH.sub.3                                                                           H      O     H    CH.sub.3                                                                            H     SPh       CH                               CH.sub.3                                                                           H      O     H    CH.sub.3                                                                            H     SPh       N                                CH.sub.3                                                                           H      O     H    CH.sub.3                                                                            SeCH.sub.3                                                                          SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           H      O     H    OCH.sub.3                                                                           SPh   SPh       CH                               H    CH.sub.3                                                                             O     H    OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               H    CH.sub.3                                                                             O     H    OCH.sub.3                                                                           H     SePh      CH                               H    CH.sub.3                                                                             O     H    OCH.sub.3                                                                           H     SPh       CH                               H    CH.sub.3                                                                             O     H    OCH.sub.3                                                                           SeCH.sub.3                                                                          SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           CH.sub.3                                                                             O     H    OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           CH.sub.3                                                                             O     H    OCH.sub.3                                                                           H     SPh       CH                               CH.sub.3                                                                           H      O     CH.sub.3                                                                           OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               H    H      S     H    OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               H    H      S     H    OCH.sub.3                                                                           H     SePh      CH                               H    H      S     H    OCH.sub.3                                                                           H     SPh       CH                               CH.sub.3                                                                           H      S     H    OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           H      S     H    OCH.sub.3                                                                           H     SePh      CH                               CH.sub.3                                                                           H      S     H    OCH.sub.3                                                                           H     SPh       CH                               CH.sub.3                                                                           H      S     H    OCH.sub.3                                                                           H     SO.sub.2 Ph                                                                             CH                               CH.sub.3                                                                           H      S     H    CH.sub.3                                                                            H     SPh       CH                               CH.sub.3                                                                           H      S     H    CH.sub.3                                                                            H     SPh       N                                CH.sub.3                                                                           H      S     H    CH.sub.3                                                                            SeCH.sub.3                                                                          SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           H      S     H    OCH.sub.3                                                                           SPh   SPh       CH                               H    CH.sub.3                                                                             S     H    OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               H    CH.sub.3                                                                             S     H    OCH.sub.3                                                                           H     SePh      CH                               H    CH.sub.3                                                                             S     H    OCH.sub.3                                                                           H     SPh       CH                               H    CH.sub.3                                                                             S     H    OCH.sub.3                                                                           SeCH.sub.3                                                                          SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           CH.sub.3                                                                             S     H    OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           CH.sub.3                                                                             S     H    OCH.sub.3                                                                           H     SPh       CH                               CH.sub.3                                                                           H      S     CH.sub.3                                                                           OCH.sub.3                                                                           H     SeCH.sub.3                                                                              CH                               CH.sub.3                                                                           H      O     CH.sub.3                                                                           OCH.sub.3                                                                           H     OSi(CH.sub.3).sub.3                                                                     CH                               CH.sub.3                                                                           H      S     CH.sub.3                                                                           OCH.sub.3                                                                           H     OSi(CH.sub.3).sub.3                                                                     N                                H    H      S     CH.sub.3                                                                           OCH.sub.3                                                                           H     CH.sub.2 OSi(CH.sub.3).sub.3                                                            N                                ______________________________________                                    

                  TABLE 6b                                                        ______________________________________                                         ##STR68##                                                                    R.sub.10                                                                              R.sub.11                                                                             Q.sub.2 R     X.sub.1  m.p. (°C.)                       ______________________________________                                        H       H      O       H     OCH.sub.3                                        CH.sub.3                                                                              H      O       H     OCH.sub.3                                        CH.sub.3                                                                              H      O       H     CH.sub.3                                         CH.sub.3                                                                              H      O       H     OCH.sub.2 CH.sub.3                               H       CH.sub.3                                                                             O       H     OCH.sub.3                                        CH.sub.3                                                                              CH.sub.3                                                                             O       H     OCH.sub.3                                        CH.sub.3                                                                              H      O       CH.sub.3                                                                            OCH.sub.3                                        H       H      S       H     OCH.sub.3                                        CH.sub.3                                                                              H      S       H     OCH.sub.3                                        CH.sub.3                                                                              H      S       H     CH.sub.3                                         CH.sub.3                                                                              H      S       H     OCH.sub.2 CH.sub.3                               H       CH.sub.3                                                                             S       H     OCH.sub.3                                        CH.sub.3                                                                              CH.sub.3                                                                             S       H     OCH.sub.3                                        CH.sub.3                                                                              H      S       CH.sub.3                                                                            OCH.sub.3                                        ______________________________________                                    

                  TABLE 6c                                                        ______________________________________                                         ##STR69##                                                                    R.sub.10 R.sub.11                                                                              Q.sub.1 R      A    m.p. (°C.)                        ______________________________________                                        CH.sub.3 H       O       H      A-3                                           H        H       O       H      A-3                                           CH.sub.3 CH.sub.3                                                                              O       H      A-3                                           CH.sub.3 H       O       CH.sub.3                                                                             A-3                                           CH.sub.3 H       S       H      A-3                                           H        H       S       H      A-3                                           CH.sub.3 CH.sub.3                                                                              S       H      A-3                                           H        CH.sub.3                                                                              S       H      A-3                                           H        H       O       H      A-4                                           CH.sub.3 H       O       H      A-4                                           CH.sub.3 CH.sub.3                                                                              O       H      A-4                                           CH.sub.3 H       O       CH.sub.3                                                                             A-4                                           H        CH.sub.3                                                                              O       H      A-4                                           H        H       S       H      A-4                                           CH.sub.3 H       S       H      A-4                                           CH.sub.3 CH.sub.3                                                                              S       H      A-4                                           H        CH.sub.3                                                                              S       H      A-4                                           ______________________________________                                    

                  TABLE 6d                                                        ______________________________________                                         ##STR70##                                                                    R.sub.10                                                                             R.sub.11                                                                              Q.sub.1                                                                             R    X.sub.1                                                                             E    Z    m.p. (°C.)                   ______________________________________                                        H      H       O     H    OCH.sub.3                                                                           F    CH                                       H      H       O     H    OCH.sub.3                                                                           Cl   CH                                       CH.sub.3                                                                             H       O     H    OCH.sub.3                                                                           F    CH                                       CH.sub.3                                                                             H       O     H    CH.sub.3                                                                            F    CH                                       CH.sub.3                                                                             H       O     H    CH.sub.3                                                                            F    N                                        H      CH.sub.3                                                                              O     H    OCH.sub.3                                                                           F    CH                                       H      CH.sub.3                                                                              O     H    OCH.sub.3                                                                           Br   CH                                       H      H       S     H    OCH.sub.3                                                                           F    CH                                       CH.sub.3                                                                             H       S     H    OCH.sub.3                                                                           F    CH                                       CH.sub.3                                                                             H       S     H    OCH.sub.3                                                                           Cl   CH                                       CH.sub.3                                                                             H       S     H    CH.sub.3                                                                            Br   CH                                       CH.sub.3                                                                             CH.sub.3                                                                              S     H    OCH.sub.3                                                                           F    CH                                       CH.sub.3                                                                             H       S     H    OCH.sub.3                                                                           F    N                                        ______________________________________                                    

                  TABLE 6e                                                        ______________________________________                                         ##STR71##                                                                                                                m.p.                              Q.sub.2                                                                           R.sub.10                                                                             R.sub.11                                                                             R X    Z    G             (°C.)                      ______________________________________                                        O   H      H      H OCH.sub.3                                                                          CH   CH(OCH.sub.2 CH.sub.2 O)                        O   H      H      H CH.sub.3                                                                           CH   CH(OCH.sub.2 CH.sub.2 O)                        O   CH.sub.3                                                                             CH.sub.3                                                                             H OCH.sub.3                                                                          N    CH(OCH.sub.2 CH.sub.2 O)                        O   CH.sub.3                                                                             H      H OCH.sub.3                                                                          CH   CH(OCH.sub.3).sub.2                             S   H      H      H OCH.sub.3                                                                          CH   CH(OCH.sub.2 CH.sub.2 O)                        S   CH.sub.3                                                                             H      H OCH.sub.3                                                                          CH   C.sub.6 H.sub.5                                 S   H      H      H CH.sub.3                                                                           CH   CH(OCH.sub.2 CH.sub.2 O)                        S   H      H      H OCH.sub.3                                                                          CH   CH(OCH.sub.3).sub.2                             ______________________________________                                    

                                      TABLE 7a                                    __________________________________________________________________________     ##STR72##                                                                    R.sub.9                                                                          R.sub.12                                                                             R  m X     T   Y       Z  m.p. (°C.)                         __________________________________________________________________________    H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                           H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   SePh    CH                                           H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                           CH                                           H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   OPh     CH                                           H  CH.sub.3                                                                             H  0 CH.sub.3                                                                            H   SeCH.sub.3                                                                            CH                                           H  CH.sub.3                                                                             H  0 CH.sub.3                                                                            H   SePh    CH                                           H  CH.sub.3                                                                             H  0 CH.sub.3                                                                            H   SPh     CH                                           H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   SeCH.sub.3                                                                            N                                            H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   SPh     N                                            H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                            CH                                           H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           SPh SPh     CH                                           CH.sub.3                                                                         CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 OCH.sub.3                                                                           H   SePh    CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                           CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 OCH.sub.3                                                                           H   SPh     N                                            H  CH.sub.2 CH.sub.3                                                                    H  0 OCH.sub.3                                                                           H   OPh     CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 CH.sub.3                                                                            H   SeCH.sub.3                                                                            CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 CH.sub.3                                                                            H   SePh    CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 CH.sub.3                                                                            H   SPh     CH                                           H  CH.sub.2 CH.sub.3                                                                    H  0 CH.sub.3                                                                            H   SPh     N                                            H  CH.sub.3                                                                             H  0 OCH.sub.2 CH.sub.3                                                                  H   SePh    CH                                           H  CH.sub.3                                                                             H  0 Cl    H   SPh     CH                                           H  CH.sub.3                                                                             H  0 F     H   SPh     CH                                           H  CH.sub.3                                                                             H  0 Br    H   SePh    CH                                           H  CH.sub.3                                                                             H  0 CF.sub.3                                                                            H   SePh    CH                                           H  CH.sub.3                                                                             H  0 OCHF.sub.2                                                                          H   SPh     CH                                           CH.sub.3                                                                         CH.sub.2 CH.sub.3                                                                    H  0 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  0 OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  0 OCH.sub.3                                                                           H   SePh    CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  0 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  0 OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                           CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  0 OCH.sub.3                                                                           H   OPh     CH                                           H  CH.sub.3                                                                             CH.sub.3                                                                         0 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   SePh    CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                           CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   OPh     CH                                           H  CH.sub.3                                                                             H  1 CH.sub.3                                                                            H   SeCH.sub.3                                                                            CH                                           H  CH.sub.3                                                                             H  1 CH.sub.3                                                                            H   SePh    CH                                           H  CH.sub.3                                                                             H  1 CH.sub.3                                                                            H   SPh     CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   SeCH.sub.3                                                                            N                                            H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   SPh     N                                            H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           SeCH.sub.3                                                                        SeCH.sub.3                                                                            CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           SPh SPh     CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 OCH.sub.3                                                                           H   SePh    CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                           CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 OCH.sub.3                                                                           H   SPh     N                                            H  CH.sub.2 CH.sub.3                                                                    H  1 OCH.sub.3                                                                           H   OPh     CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 CH.sub.3                                                                            H   SeCH.sub.3                                                                            CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 CH.sub.3                                                                            H   SePh    CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 CH.sub.3                                                                            H   SPh     CH                                           H  CH.sub.2 CH.sub.3                                                                    H  1 CH.sub.3                                                                            H   SPh     N                                            H  CH.sub.3                                                                             H  1 OCH.sub.2 CH.sub.3                                                                  H   SePh    CH                                           H  CH.sub.3                                                                             H  1 Cl    H   SPh     CH                                           H  CH.sub.3                                                                             H  1 F     H   SPh     CH                                           H  CH.sub.3                                                                             H  1 Br    H   SePh    CH                                           H  CH.sub.3                                                                             H  1 CF.sub.3                                                                            H   SePh    CH                                           H  CH.sub.3                                                                             H  1 OCHF.sub.2                                                                          H   SPh     CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  1 OCH.sub.3                                                                           H   SeCH.sub.3                                                                            CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  1 OCH.sub.3                                                                           H   SePh    CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  1 OCH.sub.3                                                                           H   SPh     CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  1 OCH.sub.3                                                                           H   SO.sub.2 Ph                                                                           CH                                           H  CH.sub.2 CH.sub.2 CH.sub.3                                                           H  1 OCH.sub.3                                                                           H   OPh     CH                                           H  CH.sub.3                                                                             H  0 OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                   CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   OSi(CH.sub.3).sub.3                                                                   CH                                           H  CH.sub.3                                                                             H  1 OCH.sub.3                                                                           H   CH.sub.2 OH                                                                           CH                                           CH.sub.3                                                                         CH.sub.3                                                                             H  0 CH.sub.3                                                                            H   CH.sub.2 OSi(CH.sub.3).sub.2                                                          N                                            __________________________________________________________________________

                  TABLE 7b                                                        ______________________________________                                         ##STR73##                                                                    R.sub.9                                                                              R.sub.12    R       m   X.sub.1 m.p. (°C.)                      ______________________________________                                        H      CH.sub.3    H       0   CH.sub.3                                       H      CH.sub.3    H       0   OCH.sub.3                                      H      CH.sub.3    H       0   OCH.sub.2 CH.sub.3                             CH.sub.3                                                                             CH.sub.3    H       0   OCH.sub.3                                      H      CH.sub.2 CH.sub.3                                                                         H       0   CH.sub.3                                       H      CH.sub.2 CH.sub.3                                                                         H       0   OCH.sub.3                                      H      CH.sub.2 CH.sub.3                                                                         H       0   OCH.sub.2 CH.sub.3                             H      CH.sub.2 CH.sub.2 CH.sub.3                                                                H       0   OCH.sub.3                                      H      CH.sub.2 CH.sub.2 CH.sub.3                                                                H       0   CH.sub.3                                       H      CH.sub.2 CH.sub.2 CH.sub.3                                                                H       0   OCH.sub.2 CH.sub.3                             H      CH.sub.3    H       1   CH.sub.3                                       H      CH.sub.3    H       1   OCH.sub.3                                      H      CH.sub.3    H       1   OCH.sub.2 CH.sub.3                             CH.sub.3                                                                             CH.sub.3    H       0   CH.sub.3                                       H      CH.sub.2 CH.sub.3                                                                         H       1   CH.sub.3                                       H      CH.sub.2 CH.sub.3                                                                         H       1   OCH.sub.3                                      H      CH.sub.2 CH.sub.3                                                                         H       1   OCH.sub.2 CH.sub.3                             H      CH.sub.2 CH.sub.2 CH.sub.3                                                                H       1   CH.sub.3                                       H      CH.sub.2 CH.sub.2 CH.sub.3                                                                H       1   OCH.sub.3                                      H      CH.sub.2 CH.sub.2 CH.sub.3                                                                H       1   OCH.sub.2 CH.sub.3                             H      CH.sub.3    CH.sub.3                                                                              0   OCH.sub.3                                      ______________________________________                                    

                  TABLE 7c                                                        ______________________________________                                         ##STR74##                                                                    R.sub.9  R.sub.12     R       m     m.p. (°C.)                         ______________________________________                                        H        CH.sub.3     H       0                                               H        CH.sub.2 CH.sub.3                                                                          H       0                                               H        CH.sub.2 CH.sub.2 CH.sub.3                                                                 H       0                                               CH.sub.3 CH.sub.3     H       0                                               H        CH.sub.3     CH.sub.3                                                                              0                                               CH.sub.3 CH.sub.2 CH.sub.3                                                                          H       0                                               H        CH.sub.3     H       1                                               H        CH.sub.2 CH.sub.3                                                                          H       1                                               H        CH.sub.2 CH.sub.2 CH.sub.3                                                                 H       1                                               H        CH.sub.3     CH.sub.3                                                                              1                                               ______________________________________                                    

                  TABLE 7d                                                        ______________________________________                                         ##STR75##                                                                    R.sub.9                                                                           R.sub.12   R     m   X.sub.1 E   Z    m.p. (°C.)                   ______________________________________                                        H   CH.sub.3   H     0   OCH.sub.3                                                                             Cl  CH                                       H   CH.sub.3   H     0   OCH.sub.3                                                                             Br  CH                                       H   CH.sub.2 CH.sub.3                                                                        H     0   OCH.sub.3                                                                             Cl  CH                                       H   CH.sub.2 CH.sub.3                                                                        H     0   OCH.sub.3                                                                             Br  CH                                       H   CH.sub.2 CH.sub.2 CH.sub.3                                                               H     0   OCH.sub.3                                                                             Cl  CH                                       H   CH.sub.3   H     0   OCH.sub.3                                                                             Br  N                                        H   CH.sub.3   H     1   OCH.sub.3                                                                             Cl  CH                                       H   CH.sub.3   H     1   OCH.sub.3                                                                             Br  CH                                       H   CH.sub.2 CH.sub.3                                                                        H     1   OCH.sub.3                                                                             Cl  CH                                       H   CH.sub.2 CH.sub.3                                                                        H     1   OCH.sub.3                                                                             Br  CH                                       H   CH.sub.2 CH.sub.2 CH.sub.3                                                               H     1   OCH.sub.3                                                                             Cl  CH                                       H   CH.sub.3   H     1   OCH.sub.2 CH.sub.3                                                                    Br  CH                                       H   CH.sub.2 CH.sub.3                                                                        H     1   OCH.sub.2 CH.sub.3                                                                    Cl  CH                                       H   CH.sub.2 CH.sub.2 CH.sub.3                                                               H     1   OCH.sub.2 CH.sub.3                                                                    Cl  CH                                       H   CH.sub.3   H     1   OCH.sub.3                                                                             Br  N                                        ______________________________________                                    

                  TABLE 7e                                                        ______________________________________                                         ##STR76##                                                                                                                  m.p.                            R.sub.9                                                                            R.sub.12                                                                             R     m   X     Z    G            (°C.)                    ______________________________________                                        H    CH.sub.3                                                                             H     0   OCH.sub.3                                                                           CH   CH(OCH.sub.2 CH.sub.2 O)                     CH.sub.3                                                                           CH.sub.3                                                                             H     0   CH.sub.3                                                                            CH   CH(OCH.sub.2 CH.sub.2 O)                     H    CH.sub.3                                                                             H     1   OCH.sub.3                                                                           N    CH(OCH.sub.2 CH.sub.2 O)                     H    CH.sub.3                                                                             H     1   OCH.sub.3                                                                           CH   CH(OCH.sub.3).sub.2                          H    C.sub.2 H.sub.5                                                                      H     0   OCH.sub.3                                                                           CH   C.sub.6 H.sub.5                              H    C.sub.3 H.sub.7                                                                      H     0   OCH.sub.3                                                                           CH   CH(OCH.sub.3).sub.2                          H    CH.sub.3                                                                             H     0   OCH.sub.3                                                                           CH   CH(OCH.sub.2 CH.sub.2 O)                     ______________________________________                                    

                  TABLE 8a                                                        ______________________________________                                         ##STR77##                                                                                                               m.p.                               L    m R.sub.9                                                                             R X        T     Y       Z    (°C.)                       ______________________________________                                        L-11 0 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-11 0 H     H OCH.sub.3                                                                              H     SePh    CH                                      L-11 0 H     H OCH.sub.3                                                                              H     SPh     CH                                      L-11 0 H     H OCH.sub.3                                                                              H     SO.sub.2 Ph                                                                           CH                                      L-11 0 H     H OCH.sub.3                                                                              H     OPh     CH                                      L-11 0 H     H OCH.sub.3                                                                              SeCH.sub.3                                                                          SeCH.sub.3                                                                            CH                                      L-11 0 H     H OCH.sub.3                                                                              SPh   SPh     CH                                      L-11 0 H     H OCH.sub.3                                                                              SCH.sub.3                                                                           SeCH.sub.3                                                                            CH                                      L-11 0 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            N                                       L-11 0 H     H OCH.sub.3                                                                              H     SPh     N                                       L-11 0 H     H CH.sub.3 H     SeCH.sub.3                                                                            CH                                      L-11 0 H     H CH.sub.3 H     SePh    CH                                      L-11 0 H     H CH.sub.3 H     SPh     CH                                      L-11 0 H     H CH.sub.3 H     SO.sub.2 Ph                                                                           CH                                      L-11 0 H     H OCH.sub.2 CH.sub.3                                                                     H     SPh     CH                                      L-11 0 H     H OCHF.sub.2                                                                             H     SPh     CH                                      L-11 0 H     H Cl       H     SePh    CH                                      L-11 0 H     H CF.sub.3 H     SPh     CH                                      L-11 0 CH.sub.3                                                                            H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-11 0 CH.sub.3                                                                            H OCH.sub.3                                                                              H     SPh     CH                                      L-11 1 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-11 1 H     H OCH.sub.3                                                                              H     SePh    CH                                      L-11 1 H     H OCH.sub.3                                                                              H     SPh     CH                                      L-11 1 H     H OCH.sub.3                                                                              H     SO.sub.2 Ph                                                                           CH                                      L-11 1 H     H OCH.sub.3                                                                              H     OPh     CH                                      L-11 1 H     H OCH.sub.3                                                                              SeCH.sub.3                                                                          SeCH.sub.3                                                                            CH                                      L-11 1 H     H OCH.sub.3                                                                              SPh   SPh     CH                                      L-11 1 H     H OCH.sub.3                                                                              SCH.sub.3                                                                           SeCH.sub.3                                                                            CH                                      L-11 1 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            N                                       L-11 1 H     H OCH.sub.3                                                                              H     SPh     N                                       L-11 1 H     H CH.sub.3 H     SeCH.sub.3                                                                            CH                                      L-11 1 H     H CH.sub.3 H     SePh    CH                                      L-11 1 H     H CH.sub.3 H     SPh     CH                                      L-11 1 H     H CH.sub.3 H     SO.sub.2 Ph                                                                           CH                                      L-11 1 H     H OCH.sub.2 CH.sub.3                                                                     H     SPh     CH                                      L-11 1 H     H OCHF.sub.2                                                                             H     SPh     CH                                      L-11 1 H     H Cl       H     SePh    CH                                      L-11 1 H     H CF.sub.3 H     SPh     CH                                      L-12 0 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-12 0 H     H OCH.sub.3                                                                              H     SePh    CH                                      L-12 0 H     H OCH.sub.3                                                                              H     SPh     CH                                      L-12 0 H     H OCH.sub.3                                                                              H     SO.sub.2 Ph                                                                           CH                                      L-12 0 H     H OCH.sub.3                                                                              H     OPh     CH                                      L-12 0 H     H OCH.sub.3                                                                              SeCH.sub.3                                                                          SeCH.sub.3                                                                            CH                                      L-12 0 H     H OCH.sub.3                                                                              SPh   SPh     CH                                      L-12 0 H     H OCH.sub.3                                                                              SCH.sub.3                                                                           SeCH.sub.3                                                                            CH                                      L-12 0 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            N                                       L-12 0 H     H OCH.sub.3                                                                              H     SPh     N                                       L-12 0 H     H CH.sub.3 H     SeCH.sub.3                                                                            CH                                      L-12 0 H     H CH.sub.3 H     SePh    CH                                      L-12 0 H     H CH.sub.3 H     SPh     CH                                      L-12 0 H     H CH.sub.3 H     SO.sub.2 Ph                                                                           CH                                      L-12 0 H     H OCH.sub.2 CH.sub.3                                                                     H     SPh     CH                                      L-12 0 H     H OCHF.sub.2                                                                             H     SPh     CH                                      L-12 0 H     H Cl       H     SePh    CH                                      L-12 0 H     H CF.sub.3 H     SPh     CH                                      L-12 0 CH.sub.3                                                                            H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-12 0 CH.sub.3                                                                            H OCH.sub.3                                                                              H     SPh     CH                                      L-12 1 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-12 1 H     H OCH.sub.3                                                                              H     SePh    CH                                      L-12 1 H     H OCH.sub.3                                                                              H     SPh     CH                                      L-12 1 H     H OCH.sub.3                                                                              H     SO.sub.2 Ph                                                                           CH                                      L-12 1 H     H OCH.sub.3                                                                              H     OPh     CH                                      L-12 1 H     H OCH.sub.3                                                                              SeCH.sub.3                                                                          SeCH.sub.3                                                                            CH                                      L-12 1 H     H OCH.sub.3                                                                              SPh   SPh     CH                                      L-12 1 H     H OCH.sub.3                                                                              SCH.sub.3                                                                           SeCH.sub.3                                                                            CH                                      L-12 1 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            N                                       L-12 1 H     H OCH.sub.3                                                                              H     SPh     N                                       L-12 1 H     H CH.sub.3 H     SeCH.sub.3                                                                            CH                                      L-12 1 H     H CH.sub.3 H     SePh    CH                                      L-12 1 H     H CH.sub.3 H     SPh     CH                                      L-12 1 H     H CH.sub.3 H     SO.sub.2 Ph                                                                           CH                                      L-12 1 H     H OCH.sub.2 CH.sub.3                                                                     H     SPh     CH                                      L-12 1 H     H OCHF.sub.2                                                                             H     SPh     CH                                      L-12 1 H     H Cl       H     SePh    CH                                      L-12 1 H     H CF.sub.3 H     SPh     CH                                      L-13 0 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-13 0 H     H OCH.sub.3                                                                              H     SePh    CH                                      L-13 0 H     H OCH.sub.3                                                                              H     SPh     CH                                      L-13 0 H     H OCH.sub.3                                                                              H     SO.sub.2 Ph                                                                           CH                                      L-13 0 H     H OCH.sub.3                                                                              H     OPh     CH                                      L-13 0 H     H OCH.sub.3                                                                              SeCH.sub.3                                                                          SeCH.sub.3                                                                            CH                                      L-13 0 H     H OCH.sub.3                                                                              SPh   SPh     CH                                      L-13 0 H     H OCH.sub.3                                                                              SCH.sub.3                                                                           SeCH.sub.3                                                                            CH                                      L-13 0 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            N                                       L-13 0 H     H OCH.sub.3                                                                              H     SPh     N                                       L-13 0 H     H CH.sub.3 H     SeCH.sub.3                                                                            CH                                      L-13 0 H     H CH.sub.3 H     SePh    CH                                      L-13 0 H     H CH.sub.3 H     SPh     CH                                      L-13 0 H     H CH.sub.3 H     SO.sub.2 Ph                                                                           CH                                      L-13 0 H     H OCH.sub.2 CH.sub.3                                                                     H     SPh     CH                                      L-13 0 H     H OCHF.sub.2                                                                             H     SPh     CH                                      L-13 0 H     H Cl       H     SePh    CH                                      L-13 0 H     H CF.sub.3 H     SPh     CH                                      L-13 0 CH.sub.3                                                                            H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-13 0 CH.sub.3                                                                            H OCH.sub.3                                                                              H     SPh     CH                                      L-13 1 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            CH                                      L-13 1 H     H OCH.sub.3                                                                              H     SePh    CH                                      L-13 1 H     H OCH.sub.3                                                                              H     SPh     CH                                      L-13 1 H     H OCH.sub.3                                                                              H     SO.sub.2 Ph                                                                           CH                                      L-13 1 H     H OCH.sub.3                                                                              H     OPh     CH                                      L-13 1 H     H OCH.sub.3                                                                              SeCH.sub.3                                                                          SeCH.sub.3                                                                            CH                                      L-13 1 H     H OCH.sub.3                                                                              SPh   SPh     CH                                      L-13 1 H     H OCH.sub.3                                                                              SCH.sub.3                                                                           SeCH.sub.3                                                                            CH                                      L-13 1 H     H OCH.sub.3                                                                              H     SeCH.sub.3                                                                            N                                       L-13 1 H     H OCH.sub.3                                                                              H     SPh     N                                       L-13 1 H     H CH.sub.3 H     SeCH.sub.3                                                                            CH                                      L-13 1 H     H CH.sub.3 H     SePh    CH                                      L-13 1 H     H CH.sub.3 H     SPh     CH                                      L-13 1 H     H CH.sub.3 H     SO.sub.2 Ph                                                                           CH                                      L-13 1 H     H OCH.sub.2 CH.sub.3                                                                     H     SPh     CH                                      L-13 1 H     H OCHF.sub.2                                                                             H     SPh     CH                                      L-13 1 H     H Cl       H     SePh    CH                                      L-13 1 H     H CF.sub.3 H     SPh     CH                                      L-11 0 H     H OCH.sub.3                                                                              H     CH.sub.2 OH                                                                           CH                                      L-12 1 H     H OCH.sub.3                                                                              H     CH.sub.2 OH                                                                           N                                       L-13 1 H     H OCH.sub.3                                                                              H     OSi(CH.sub.3).sub.3                                                                   CH                                      ______________________________________                                    

                  TABLE 8b                                                        ______________________________________                                         ##STR78##                                                                    L      R.sub.9  R      X.sub.1  m   m.p. (°C.)                         ______________________________________                                        L-11   H        H      CH.sub.3 0                                             L-11   H        H      OCH.sub.3                                                                              0                                             L-11   H        H      OCH.sub.2 CH.sub.3                                                                     0                                             L-11   CH.sub.3 H      OCH.sub.3                                                                              0                                             L-11   H        H      CH.sub.3 1                                             L-11   H        H      OCH.sub.3                                                                              1                                             L-11   H        H      OCH.sub.2 CH.sub.3                                                                     1                                             L-12   H        H      CH.sub.3 0                                             L-12   H        H      OCH.sub.3                                                                              0                                             L-12   H        H      OCH.sub.2 CH.sub.3                                                                     0                                             L-12   CH.sub.3 H      OCH.sub.3                                                                              0                                             L-12   H        H      CH.sub.3 1                                             L-12   H        H      OCH.sub.3                                                                              1                                             L-12   H        H      OCH.sub.2 CH.sub.3                                                                     1                                             L-13   H        H      CH.sub.3 0                                             L-13   H        H      OCH.sub.3                                                                              0                                             L-13   H        H      OCH.sub.2 CH.sub.3                                                                     0                                             L-13   H        H      CH.sub.3 1                                             L-13   H        H      OCH.sub.3                                                                              1                                             L-13   H        H      OCH.sub.2 CH.sub.3                                                                     1                                             ______________________________________                                    

                  TABLE 8c                                                        ______________________________________                                         ##STR79##                                                                    L         R.sub.9                                                                              R          m   m.p. (°C.)                             ______________________________________                                        L-11      H      H          0                                                 L-11      CH.sub.3                                                                             H          0                                                 L-11      CH.sub.3                                                                             CH.sub.3   0                                                 L-11      H      H          1                                                 L-11      H      CH.sub.3   1                                                 L-12      H      H          0                                                 L-12      CH.sub.3                                                                             H          0                                                 L-12      CH.sub.3                                                                             CH.sub.3   0                                                 L-12      H      H          1                                                 L-12      H      CH.sub.3   1                                                 L-13      H      H          0                                                 L-13      CH.sub.3                                                                             H          0                                                 L-13      H      H          1                                                 ______________________________________                                    

                  TABLE 8d                                                        ______________________________________                                         ##STR80##                                                                    L     R.sub.9                                                                              R       m   X.sub.1 E   Z     m.p. (°C.)                  ______________________________________                                        L-12  H      H       0   OCH.sub.3                                                                             Cl  CH                                       L-12  H      H       0   OCH.sub.3                                                                             Br  CH                                       L-12  H      H       0   CH.sub.3                                                                              Cl  CH                                       L-12  H      H       0   CH.sub.2 CH.sub.3                                                                     Br  CH                                       L-12  H      H       0   OCH.sub.3                                                                             Cl  N                                        L-12  H      H       1   OCH.sub.3                                                                             Cl  CH                                       L-12  H      H       1   OCH.sub.3                                                                             Br  CH                                       L-12  H      H       1   CH.sub.3                                                                              Cl  CH                                       L-12  H      H       1   CH.sub.2 CH.sub.3                                                                     Br  CH                                       L-12  H      H       1   OCH.sub.3                                                                             Cl  N                                        L-12  CH.sub.3                                                                             H       0   OCH.sub.3                                                                             Cl  CH                                       L-12  H      CH.sub.3                                                                              0   OCH.sub.3                                                                             Cl  CH                                       L-13  H      H       0   OCH.sub.3                                                                             Cl  CH                                       L-13  H      H       0   OCH.sub.3                                                                             Br  CH                                       L-13  H      H       1   OCH.sub.3                                                                             Cl  CH                                       L-13  H      H       1   OCH.sub.3                                                                             Br  CH                                       ______________________________________                                    

                  TABLE 8e                                                        ______________________________________                                         ##STR81##                                                                                                                  m.p.                            L    R.sub.9                                                                              R     m   X     Z    G            (°C.)                    ______________________________________                                        L-11 H      H     0   OCH.sub.3                                                                           CH   CH(OCH.sub.3).sub.2                          L-11 H      H     0   CH.sub.3                                                                            CH   CH(OCH.sub.2 CH.sub.2 O)                     L-11 H      H     1   OCH.sub.3                                                                           N    CH(OCH.sub.2 CH.sub.2 O)                     L-11 CH.sub.3                                                                             H     1   OCH.sub.3                                                                           CH   CH(OCH.sub.3).sub.2                          L-12 H      H     0   OCH.sub.3                                                                           CH   CH(OCH.sub.3).sub.2                          L-12 H      H     1   OCH.sub.3                                                                           CH   CH(OCH.sub.2 CH.sub.2 O)                     L-13 H      H     0   OCH.sub.3                                                                           CH   C.sub.6 H.sub.5                              L-13 H      H     1   OCH.sub.3                                                                           CH   CH(OCH.sub.2 CH.sub.2 O)                     ______________________________________                                    

                  TABLE 9a                                                        ______________________________________                                         ##STR82##                                                                    R.sub.12 R     X        T     Y         Zm.p. (°C).                    ______________________________________                                        CH.sub.3 H     OCH.sub.3                                                                              H     SeCH.sub.3                                                                              CH                                    CH.sub.3 H     OCH.sub.3                                                                              H     SePh      CH                                    CH.sub.3 H     CH.sub.3 H     SPh       CH                                    CH.sub.3 H     CH.sub.3 H     SO.sub.2 Ph                                                                             CH                                    CH.sub.3 H     OCH.sub.3                                                                              H     OPh       CH                                    CH.sub.3 H     OCH.sub.3                                                                              SeCH.sub.3                                                                          SeCH.sub.3                                                                              CH                                    CH.sub.3 H     OCH.sub.3                                                                              SPh   SPh       CH                                    CH.sub.3 H     OCH.sub.3                                                                              H     SPh       N                                     CH.sub.2 CH.sub.3                                                                      H     OCH.sub.3                                                                              H     SeCH.sub.3                                                                              CH                                    CH.sub.2 CH.sub.3                                                                      H     OCH.sub.3                                                                              H     SPh       CH                                    CH.sub.2 CH.sub.3                                                                      H     OCH.sub.3                                                                              H     OPh       CH                                    CH.sub.2 CH.sub.3                                                                      H     CH.sub.3 H     SePh      CH                                    CH.sub.2 CH.sub.3                                                                      H     CH.sub.3 H     SO.sub.2 Ph                                                                             CH                                    CH.sub.2 CH.sub.2 CH.sub.3                                                             H     OCH.sub.3                                                                              H     SeCH.sub.3                                                                              CH                                    CH.sub.2 CH.sub.2 CH.sub.3                                                             H     OCH.sub.3                                                                              H     OPh       CH                                    CH.sub.2 CH.sub.2 CH.sub.3                                                             H     OCH.sub.3                                                                              SeCH.sub.3                                                                          SeCH.sub.3                                                                              CH                                    CH.sub.2 CH.sub.2 CH.sub.3                                                             H     OCH.sub.3                                                                              H     SPh       N                                     CH.sub.2 CH.sub.2 CH.sub.3                                                             H     OCH.sub.3                                                                              SPh   SPh       N                                     CH.sub.3 H     Cl       H     SPh       CH                                    CH.sub.3 H     CF.sub.3 H     SePH      CH                                    CH.sub.3 H     OCF.sub.2 H                                                                            H     OPh       CH                                    CH.sub.3 H     OCH.sub.3                                                                              H     CH.sub.2 OH                                                                             CH                                    CH.sub.2 CH.sub.3                                                                      H     CH.sub.3 SCH.sub.3                                                                           CH.sub.2 OSi(CH.sub.3).sub.3                                                            N                                     ______________________________________                                    

                  TABLE 9b                                                        ______________________________________                                         ##STR83##                                                                    R.sub.12   R          X.sub.1   m.p. (°C.)                             ______________________________________                                        CH.sub.3   H          OCH.sub.3                                               CH.sub.3   H          CH.sub.3                                                CH.sub.3   H          OCH.sub.2 CH.sub.3                                      CH.sub.2 CH.sub.3                                                                        H          OCH.sub.3                                               CH.sub.2 CH.sub.3                                                                        H          OCH.sub.2 CH.sub.3                                      CH.sub.2 CH.sub.2 CH.sub.3                                                               H          OCH.sub.3                                               CH.sub.2 CH.sub.2 CH.sub.3                                                               H          CH.sub.3                                                CH.sub.3   CH.sub.3   OCH.sub.3                                               ______________________________________                                    

                  TABLE 9c                                                        ______________________________________                                         ##STR84##                                                                    R.sub.12         R      m.p. (°C.)                                     ______________________________________                                        CH.sub.3         H                                                            CH.sub.2 CH.sub.3                                                                              H                                                            CH.sub.2 CH.sub.2 CH.sub.3                                                                     H                                                            CH.sub.3         CH.sub.3                                                     ______________________________________                                    

                  TABLE 9d                                                        ______________________________________                                         ##STR85##                                                                    R.sub.12 R        X.sub.1 E     Z    m.p. (°C.)                        ______________________________________                                        CH.sub.3 H        CH.sub.3                                                                              Cl    CH                                            CH.sub.3 H        CH.sub.3                                                                              Br    CH                                            CH.sub.3 H        OCH.sub.3                                                                             Cl    CH                                            CH.sub.3 H        OCH.sub.3                                                                             Cl    N                                             CH.sub.3 H        OCH.sub.3                                                                             Br    N                                             CH.sub.2 CH.sub.3                                                                      H        CH.sub.3                                                                              Cl    CH                                            CH.sub.2 CH.sub.3                                                                      H        OCH.sub.3                                                                             Cl    CH                                            CH.sub.2 CH.sub.3                                                                      H        OCH.sub.3                                                                             Br    CH                                            CH.sub.2 CH.sub.2 CH.sub.3                                                             H        OCH.sub.3                                                                             Cl    CH                                            CH.sub.3 CH.sub.3 OCH.sub.3                                                                             Cl    CH                                            ______________________________________                                    

                  TABLE 9e                                                        ______________________________________                                         ##STR86##                                                                    R.sub.12                                                                            R      X       Z    G            m.p. (°C.)                      ______________________________________                                        CH.sub.3                                                                            H      OCH.sub.3                                                                             CH   CH(OCH.sub.2 CH.sub.2 O)                            CH.sub.3                                                                            H      CH.sub.3                                                                              CH   CH(OCH.sub.2 CH.sub.2 O)                            C.sub.2 H.sub.5                                                                     H      OCH.sub.3                                                                             N    CH(OCH.sub.3).sub.2                                 C.sub.2 H.sub.5                                                                     H      CH.sub.3                                                                              CH   CH(OCH.sub.3).sub.2                                 C.sub.3 H.sub.7 - -n                                                                H      OCH.sub.3                                                                             CH   CH(OCH.sub.3).sub.2                                 CH.sub.3                                                                            CH.sub.3                                                                             OCH.sub.3                                                                             CH   CH(OCH.sub.2 CH.sub.2 O)                            CH.sub.3                                                                            H      OCH.sub.3                                                                             CH   C.sub.6 H.sub.5                                     ______________________________________                                    

                                      TABLE 10a                                   __________________________________________________________________________     ##STR87##                                                                    L   R.sub.13                                                                              R.sub.14                                                                          R   X      T    Y     Z   m.p. (°C.)                   __________________________________________________________________________    L-15                                                                              H       --  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                          CH                                      L-15                                                                              H       --  H   OCH.sub.3                                                                            H    SePh  CH                                      L-15                                                                              H       --  H   OCH.sub.3                                                                            H    SPh   CH                                      L-15                                                                              H       --  H   OCH.sub.3                                                                            H    OPh   CH                                      L-15                                                                              H       --  H   CH.sub.3                                                                             H    SPh   CH                                      L-15                                                                              H       --  H   OCH.sub.3                                                                            H    SPh   N                                       L-15                                                                              H       --  H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                          CH                                      L-15                                                                              H       --  H   OCH.sub.3                                                                            SPh  SPh   CH                                      L-15                                                                              CH.sub.3                                                                              --  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                          CH                                      L-15                                                                              CH.sub.3                                                                              --  H   OCH.sub.3                                                                            H    SePh  CH                                      L-15                                                                              CH.sub.3                                                                              --  H   OCH.sub.3                                                                            H    SPh   CH                                      L-15                                                                              CH.sub.3                                                                              --  H   CH.sub.3                                                                             H    SeCH.sub.3                                                                          CH                                      L-15                                                                              CH.sub.3                                                                              --  H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                         N                                       L-15                                                                              CH.sub.3                                                                              --  H   OCH.sub.3                                                                            SPh  SPh   CH                                      L-15                                                                              CH.sub.2 CH.sub.3                                                                     --  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                          CH                                      L-15                                                                              CH.sub.2 CH.sub.3                                                                     --  H   OCH.sub.3                                                                            H    SPh   CH                                      L-15                                                                              CH.sub.2 CH.sub.3                                                                     --  H   CH.sub.3                                                                             H    OPh   CH                                      L-15                                                                              CH.sub.2 CH.sub.2 CH.sub.3                                                            --  H   OCH.sub.3                                                                            H    SPh   CH                                      L-15                                                                              CH.sub.3                                                                              --  CH.sub.3                                                                          OCH.sub.3                                                                            H    SePh  CH                                      L-15                                                                              H       --  H   OCH.sub.2 CH.sub.3                                                                   H    SPh   CH                                      L-15                                                                              H       --  H   F      H    SPh   CH                                      L-15                                                                              H       --  H   Br     H    SeCH.sub.3                                                                          CH                                      L-15                                                                              H       --  H   CF.sub.3                                                                             H    SPh   CH                                      L-15                                                                              H       --  H   OCHF.sub.2                                                                           H    SeCH.sub.3                                                                          CH                                      L-15                                                                              H       --  CH.sub.3                                                                          OCH.sub.3                                                                            SPh  SPh   N                                       L-16                                                                              H       --  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                          CH                                      L-16                                                                              H       --  H   OCH.sub.3                                                                            H    SePH  CH                                      L-16                                                                              H       --  H   OCH.sub.3                                                                            H    SPh   CH                                      L-16                                                                              H       --  H   OCH.sub. 3                                                                           H    OPh   CH                                      L-16                                                                              H       --  H   CH.sub.3                                                                             H    SPh   CH                                      L-16                                                                              H       --  H   OCH.sub.3                                                                            H    SPh   N                                       L-16                                                                              H       --  H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                          CH                                      L-16                                                                              H       --  H   OCH.sub.3                                                                            SPh  SPh   CH                                      L-16                                                                              CH.sub.3                                                                              --  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                          CH                                      L-16                                                                              CH.sub.3                                                                              --  H   OCH.sub.3                                                                            H    SePh  CH                                      L-16                                                                              CH.sub.3                                                                              --  H   OCH.sub.3                                                                            H    SPh   CH                                      L-16                                                                              CH.sub.3                                                                              --  H   CH.sub.3                                                                             H    SeCH.sub.3                                                                          CH                                      L-16                                                                              CH.sub.3                                                                              --  H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                         N                                       L-16                                                                              CH.sub.3                                                                              --  H   OCH.sub.3                                                                            SPh  SPh   CH                                      L-16                                                                              CH.sub.2 CH.sub.3                                                                     --  H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                          CH                                      L-16                                                                              CH.sub.2 CH.sub.3                                                                     --  H   OCH.sub.3                                                                            H    SPh   CH                                      L-16                                                                              CH.sub.2 CH.sub.3                                                                     --  H   CH.sub.3                                                                             H    OPh   CH                                      L-16                                                                              CH.sub.2 CH.sub.2 CH.sub.3                                                            --  H   OCH.sub.3                                                                            H    SPh   CH                                      L-16                                                                              CH.sub.3                                                                              --  CH.sub.3                                                                          OCH.sub.3                                                                            H    SePh  CH                                      L-16                                                                              H       --  H   OCH.sub.2 CH.sub.3                                                                   H    SPh   CH                                      L-16                                                                              H       --  H   F      H    SPh   CH                                      L-16                                                                              H       --  H   Br     H    SeCH.sub.3                                                                          CH                                      L-16                                                                              H       --  H   CF.sub.3                                                                             H    SPh   CH                                      L-16                                                                              H       --  H   OCHF.sub.2                                                                           H    SeCH.sub.3                                                                          CH                                      L-16                                                                              H       --  CH.sub.3                                                                          OCH.sub.3                                                                            SPh  SPh   N                                       L-17                                                                              H       H   H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                          CH                                      L-17                                                                              H       H   H   OCH.sub.3                                                                            H    SePh  CH                                      L-17                                                                              H       H   H   OCH.sub.3                                                                            H    SPh   CH                                      L-17                                                                              H       H   H   OCH.sub.3                                                                            H    OPh   CH                                      L-17                                                                              H       H   H   CH.sub.3                                                                             H    SPh   CH                                      L-17                                                                              CH.sub.3                                                                              H   H   OCH.sub.3                                                                            H    SPh   N                                       L-17                                                                              CH.sub.3                                                                              H   H   OCH.sub.3                                                                            SeCH.sub.3                                                                         SeCH.sub.3                                                                          CH                                      L-17                                                                              CH.sub.3                                                                              H   H   OCH.sub.3                                                                            SPh  SPh   CH                                      L-17                                                                              H       CH.sub.3                                                                          H   OCH.sub.3                                                                            H    SeCH.sub.3                                                                          CH                                      L-17                                                                              H       CH.sub.3                                                                          H   OCH.sub.3                                                                            H    SePh  CH                                      L-17                                                                              H       CH.sub.3                                                                          H   OCH.sub.3                                                                            H    SPh   CH                                      L-17                                                                              H       CH.sub.3                                                                          H   CH.sub.3                                                                             H    SeCH.sub.3                                                                          CH                                      L-17                                                                              H       CH.sub.3                                                                          H   CH.sub.3                                                                             H    SO.sub.2 Ph                                                                         N                                       L-17                                                                              CH.sub.3                                                                              CH.sub.3                                                                          H   OCH.sub.3                                                                            SPh  SPh   CH                                      L-17                                                                              CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                          OCH.sub.3                                                                            H    SePh  CH                                      L-17                                                                              CH.sub.3                                                                              H   H   OCH.sub.2 CH.sub.3                                                                   H    SPh   CH                                      L-17                                                                              CH.sub.3                                                                              H   H   F      H    SPh   CH                                      L-17                                                                              CH.sub.3                                                                              H   H   Br     H    SeCH.sub.3                                                                          CH                                      L-17                                                                              CH.sub.3                                                                              H   H   CF.sub.3                                                                             H    SPh   CH                                      L-17                                                                              CH.sub.3                                                                              H   H   OCHF.sub.2                                                                           H    SeCH.sub.3                                                                          CH                                      L-17                                                                              CH.sub.3                                                                              H   CH.sub.3                                                                          OCH.sub.3                                                                            SPh  SPh   N                                       L-15                                                                              CH.sub.3                                                                              --  CH.sub.3                                                                          OCH.sub.3                                                                            H    CH.sub.2 OH                                                                         CH                                      L-16                                                                              CH.sub.3                                                                              --  CH.sub.3                                                                          OCH.sub.3                                                                            H    CH.sub.2 OH                                                                         N                                       L-17                                                                              CH.sub.3                                                                              H   CH.sub.3                                                                          OCH.sub.3                                                                            H    CH.sub.2 OH                                                                         N                                       __________________________________________________________________________

                  TABLE 10b                                                       ______________________________________                                         ##STR88##                                                                    L     R.sub.13   R.sub.14                                                                              R    X.sub.1  m.p. (°C.)                      ______________________________________                                        L-15  H          --      H    CH.sub.3                                        L-15  H          --      H    OCH.sub.3                                       L-15  H          --      H    OCH.sub.2 CH.sub.3                              L-15  CH.sub.3   --      H    CH.sub.3                                        L-15  CH.sub.3   --      H    OCH.sub.3                                       L-15  CH.sub.3   --      H    OCH.sub.2 CH.sub.3                              L-15  CH.sub.2 CH.sub.3                                                                        --      H    CH.sub.3                                        L-15  CH.sub.2 CH.sub.3                                                                        --      H    OCH.sub.3                                       L-15  CH.sub.2 CH.sub.3                                                                        --      H    OCH.sub.2 CH.sub.3                              L-15  CH.sub.2 CH.sub.2 CH.sub.3                                                               --      H    OCH.sub.3                                       L-15  CH.sub.3   --      CH.sub.3                                                                           OCH.sub.3                                       L-15  H          --      CH.sub.3                                                                           OCH.sub.3                                       L-16  H          --      H    CH.sub.3                                        L-16  H          --      H    OCH.sub.3                                       L-16  H          --      H    OCH.sub.2 CH.sub.3                              L-16  CH.sub.3   --      H    CH.sub.3                                        L-16  CH.sub.3   --      H    OCH.sub.3                                       L-16  CH.sub.3   --      H    OCH.sub.2 CH.sub.3                              L-16  CH.sub.2 CH.sub.3                                                                        --      H    CH.sub.3                                        L-16  CH.sub.2 CH.sub.3                                                                        --      H    OCH.sub.3                                       L-16  CH.sub.2 CH.sub.3                                                                        --      H    OCH.sub.2 CH.sub.3                              L-16  CH.sub.2 CH.sub.2 CH.sub.3                                                               --      H    OCH.sub.3                                       L-16  CH.sub.3   --      CH.sub.3                                                                           OCH.sub.3                                       L-16  H          --      CH.sub.3                                                                           OCH.sub.3                                       L-17  H          H       H    CH.sub.3                                        L-17  H          H       H    OCH.sub.3                                       L-17  H          H       H    OCH.sub.2 CH.sub.3                              L-17  CH.sub.3   CH.sub.3                                                                              H    CH.sub.3                                        L-17  CH.sub.3   CH.sub.3                                                                              H    OCH.sub.3                                       L-17  CH.sub.3   CH.sub.3                                                                              H    OCH.sub.2 CH.sub.3                              L-17  CH.sub.3   CH.sub.3                                                                              CH.sub.3                                                                           OCH.sub.3                                       L-17  CH.sub.3   H       CH.sub.3                                                                           OCH.sub.3                                       ______________________________________                                    

                  TABLE 10c                                                       ______________________________________                                         ##STR89##                                                                    L     R.sub.13    R.sub.14    R    m.p. (°C.)                          ______________________________________                                        L-15  H           --          H                                               L-15  CH.sub.3    --          H                                               L-15  CH.sub.2 CH.sub.3                                                                         --          H                                               L-15  CH.sub.2 CH.sub.2 CH.sub.3                                                                --          H                                               L-15  CH.sub.3    --          CH.sub.3                                        L-16  H           --          H                                               L-16  CH.sub.3    --          H                                               L-16  CH.sub.2 CH.sub.3                                                                         --          H                                               L-16  CH.sub.2 CH.sub.2 CH.sub.3                                                                --          H                                               L-16  CH.sub.3    --          CH.sub.3                                        L-17  H           H           H                                               L-17  H           CH.sub.3    H                                               L-17  H           CH.sub.2 CH.sub.3                                                                         H                                               L-17  CH.sub.3    CH.sub.2 CH.sub.2 CH.sub.3                                                                H                                               L-17  CH.sub.3    CH.sub.3    CH.sub.3                                        ______________________________________                                    

                  TABLE 10d                                                       ______________________________________                                         ##STR90##                                                                                                                  m.p.                            L    R.sub.13   R.sub.14                                                                             R    X.sub.1 E    Z    (°C.)                    ______________________________________                                        L-15 H          --     H    OCH.sub.3                                                                             Cl   CH                                   L-15 H          --     H    OCH.sub.3                                                                             Br   CH                                   L-15 H          --     H    OCH.sub.3                                                                             Cl   N                                    L-15 H          --     H    CH.sub.3                                                                              Cl   CH                                   L-15 H          --     H    OCH.sub.2 CH.sub.3                                                                    Cl   CH                                   L-15 CH.sub.3   --     H    OCH.sub.3                                                                             Cl   CH                                   L-15 CH.sub.3   --     H    OCH.sub.3                                                                             Br   CH                                   L-15 CH.sub.3   --     H    CH.sub.3                                                                              Cl   CH                                   L-15 CH.sub.3   --     H    CH.sub.3                                                                              Cl   N                                    L-15 CH.sub.2 CH.sub.3                                                                        --     H    OCH.sub.3                                                                             Cl   CH                                   L-15 CH.sub.2 CH.sub.3                                                                        --     H    OCH.sub.3                                                                             Br   CH                                   L-15 CH.sub.2 CH.sub. 3                                                                       --     H    OCH.sub.3                                                                             Cl   N                                    L-15 CH.sub.2 CH.sub.3                                                                        --     H    CH.sub.3                                                                              Cl   CH                                   L-15 CH.sub.2 CH.sub.2 CH.sub.3                                                               --     H    OCH.sub.3                                                                             Cl   CH                                   L-15 CH.sub.2 CH.sub.2 CH.sub.3                                                               --     H    OCH.sub.3                                                                             Cl   N                                    L-15 H          --     CH.sub.3                                                                           OCH.sub.3                                                                             Cl   CH                                   L-15 CH.sub.3   --     CH.sub.3                                                                           OCH.sub.3                                                                             Br   CH                                   L-16 H          --     H    OCH.sub.3                                                                             Cl   CH                                   L-16 H          --     H    OCH.sub.3                                                                             Br   CH                                   L-16 H          --     H    OCH.sub.3                                                                             Cl   N                                    L-16 H          --     H    CH.sub.3                                                                              Cl   CH                                   L-16 H          --     H    OCH.sub.2 CH.sub.3                                                                    Cl   CH                                   L-16 CH.sub.3   --     H    OCH.sub.3                                                                             Cl   CH                                   L-16 CH.sub.3   --     H    OCH.sub.3                                                                             Br   CH                                   L-16 CH.sub.3   --     H    CH.sub.3                                                                              Cl   CH                                   L-16 CH.sub.3   --     H    CH.sub.3                                                                              Cl   N                                    L-16 CH.sub.2 CH.sub.3                                                                        --     H    OCH.sub.3                                                                             Cl   CH                                   L-16 CH.sub.2 CH.sub.3                                                                        --     H    OCH.sub.3                                                                             Br   CH                                   L-16 CH.sub.2 CH.sub.3                                                                        --     H    OCH.sub.3                                                                             Cl   N                                    L-16 CH.sub.2 CH.sub.3                                                                        --     H    CH.sub.3                                                                              Cl   CH                                   L-16 CH.sub.2 CH.sub.2 CH.sub.3                                                               --     H    OCH.sub.3                                                                             Cl   CH                                   L-16 CH.sub.2 CH.sub.2 CH.sub.3                                                               --     H    OCH.sub.3                                                                             Cl   N                                    L-16 H          --     CH.sub.3                                                                           OCH.sub.3                                                                             Cl   CH                                   L-16 CH.sub.3   --     CH.sub.3                                                                           OCH.sub.3                                                                             Br   CH                                   ______________________________________                                    

                                      TABLE 10e                                   __________________________________________________________________________     ##STR91##                                                                    L   R.sub.13                                                                            R.sub.14                                                                          R   X    Z   G           m.p. (°C.)                      __________________________________________________________________________    L-15                                                                              H     --  H   OCH.sub.3                                                                          CH  CH(OCH.sub.2 CH.sub.2 O)                           L-15                                                                              CH.sub.3                                                                            --  CH.sub.3                                                                          OCH.sub.3                                                                          CH  CH(OCH.sub.3).sub.2                                L-15                                                                              H     --  H   CH.sub.3                                                                           CH  CH(OCH.sub.3).sub.2                                L-15                                                                              C.sub.3 H.sub.7 -n                                                                  --  H   OCH.sub.3                                                                          N   CH(OCH.sub.3).sub.2                                L-16                                                                              H     --  H   OCH.sub.3                                                                          CH  CH(OCH.sub.3).sub.2                                L-16                                                                              CH.sub.3                                                                            --  H   OCH.sub.3                                                                          CH  C.sub.6 H.sub.5                                    L-17                                                                              H     H   H   OCH.sub.3                                                                          CH  CH(OCH.sub.2 CH.sub.2 O)                           L-17                                                                              CH.sub.3                                                                            CH.sub.3                                                                          H   OCH.sub.3                                                                          CH  CH(OCH.sub.3).sub.2                                L-15                                                                              H     --  H   OCH.sub.3                                                                          CH  C.sub.6 H.sub.5                                    __________________________________________________________________________

FORMULATIONS

Useful formulations of the compounds of Formula I can be prepared inconventional ways. They include dusts, granules, pellets, solutions,suspensions, emulsions, wettable powders, emulsifiable concentrates andthe like. Many of these may be applied directly. Sprayable formulationscan be extended in suitable media and used at spray volumes of from afew points to several hundred gallons per acre. High strengthcompositions are primarily used as intermediates for furtherformulation. The formulations, broadly, contain about 1% to 99% byweight of active ingredient(s) and at least one of (a) about 0.1% to 20%surfactant(s) and (b) about 5% to 99% solid or liquid diluent(s). Morespecifically, they will contain these ingredients in the followingapproximate proportions:

    ______________________________________                                                    Active  Percent by Weight                                                     Ingredient                                                                            Diluent(s)                                                                              Surfactant(s)                                   ______________________________________                                        Wettable Powders                                                                            20-90      0-74     1-10                                        Oil Suspensions,                                                                             5-50     40-95     0-15                                        Emulsions, Solutions,                                                         (including Emulsifiable                                                       Concentrates)                                                                 Aqueous Suspension                                                                          10-50     40-84     1-20                                        Dusts          1-25     70-99     0-5                                         Granules and Pellets                                                                         1-95      5-99     0-15                                        High Strength 90-99      0-10     0-2                                         Compositions                                                                  ______________________________________                                    

Lower or higher levels of active ingredient can, of course, be presentdepending on the intended use and the physical properties of thecompound. Higher ratios of surfactant to active ingredient are sometimesdesirable, and are achieved by incorporation into the formulation or bytank mixing.

Typical solid diluents are described in Watkins, et al., "Handbook ofInsecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books,Caldwell, N.J., but other solids, either mined or manufactured, may beused. The more absorptive diluents are preferred for wettable powdersand the denser ones for dusts. Typical liquid diluents and solvents aredescribed in Marsden, "Solvents Guide," 2nd Ed., Interscience, New York,1950. Solubility under 0.1% is preferred for suspension concentrates;solution concentrates are preferably stable against phase separation at0° C. "McCutcheon's Detergents and Emulsifiers Annual", MC PublishingCorp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia ofSurface Active Agents", Chemical Publishing Co., Inc., New York, 1964,list surfactants and recommended uses. All formulations can containminor amounts of additives to reduce foam, corrosion, microbiologicalgrowth, etc. Preferably, ingredients should be approved by the U.S.Environmental Protection Agency for the use intended.

The methods of making such compositions are well known. Solutions areprepared by simply mixing the ingredients. Fine solid compositions aremade by blending and, usually, grinding as in a hammer or fluid energymill. Suspensions are prepared by wet milling (see, for example,Littler, U.S. Pat. No. 3,060,084). Granules and pellets may be made byspraying the active material upon preformed granular carriers or byagglomeration techniques. See J. E. Browning, "Agglomeration", ChemicalEngineering, Dec. 4, 1967, pp. 147ff. and "Perry's Chemical Engineer'sHandbook", 4th Edn., McGraw-Hill, N.Y., 1963, pp. 8-57ff.

For further information regarding the art of formulation, see forexample:

H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16through Col. 7, line 19 and Examples 10 through 41;

R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58,132, 138-140, 162-164, 166, 167 and 169-182;

H. Gysin and E. Knusli, U.S. Pat. No. 2,891,855, June 23, 1959, Col. 3,line 66 through Col. 5, line 17 and Examples 1-4;

G. C. Klingman, "Weed Control as a Science", John Wiley and Sons, Inc.,New York, 1961, pp. 81-96; and

J. D. Fryer and S. A. Evans, "Weed Control Handbook", 5th Ed., BlackwellScientific Publications, Oxford, 1968, pp. 101-103.

In the following examples, all parts are by weight unless otherwiseindicated.

EXAMPLE 14

    ______________________________________                                        Wettable Powder                                                               ______________________________________                                        2-[[[4-methoxy-6-(phenoxymethyl)pyrimidin-2-yl]amino-                                                     50%                                               carbonyl]aminosulfonyl]benzoic acid, methyl                                   ester                                                                         sodium alkylnaphthalenesulfonate                                                                          2%                                                sodium ligninsulfonate      2%                                                synthetic amorphous silica  3%                                                kaolinite                   43%                                               The ingredients are blended and hammer-milled.                                ______________________________________                                    

EXAMPLE 15

    ______________________________________                                        High Strength Concentrate                                                     ______________________________________                                        2-[[[4-methoxy-6-(phenoxymethyl)pyrimidin-2-yl]amino-                                                     98.5%                                             carbonyl]aminosulfonyl]benzoic acid, methyl                                   ester                                                                         silica aerogel              0.5%                                              synthetic amorphous fine silica                                                                           1.0%                                              ______________________________________                                    

The ingredients are blended and ground in a hammer-mill to produce ahigh strength concentrate essentially all passing a U.S.S. No. 50 screen(0.3 mm opening). This material may be formulated in a variety of ways.

EXAMPLE 16

    ______________________________________                                        Dust                                                                          ______________________________________                                        Wettable powder of Example 14                                                                       10%                                                     pyrophyllite (powder) 90%                                                     ______________________________________                                    

The wettable powder and the pyrophyllite diluent are thoroughly blendedand then packaged. The product is suitable for use as a dust.

EXAMPLE 17

    ______________________________________                                        Aqueous Suspension                                                            ______________________________________                                        2-[[[bis(4,6-trifluoromethyl)pyrimidin-2-yl]amino-                                                       25%                                                carbonyl]aminosulfonyl]benzoic acid, methyl                                   ester                                                                         hydrated attapulgite        3%                                                crude calcium ligninsulfonate                                                                            10%                                                water                      62%                                                ______________________________________                                    

The ingredients are ground together in a ball, sand or roller mill untilthe solid particles have been reduced to diameters under 10 microns.

EXAMPLE 18

    ______________________________________                                        Solution                                                                      ______________________________________                                        2-[[[4-methoxy-6-(methylselenylmethyl)pyrimidin-2-yl]-                                                    30%                                               aminocarbonyl]aminosulfonyl]benzoic acid, methyl                              ester                                                                         dimethylformamide           70%                                               ______________________________________                                    

The ingredients are combined and stirred to produce a solution, whichcan be used for low volume applications.

EXAMPLE 19

    ______________________________________                                        Granule                                                                       ______________________________________                                        Wettable Powder of Example 14                                                                       50%                                                     sugar                 50%                                                     ______________________________________                                    

The ingredients are blended in a rotating or fluid bed mixer and watersprayed on to accomplish granulation. When most of the material hasreached the desired range of 1.0 to 0.42 mm (U.S.S. #18 to 40 sieves),the granules are removed, dried, and screened. Oversize material iscrushed to produce additional material in the desired range. Thesegranules contain 25% active ingredient.

UTILITY

Test results indicate that the compounds of the present invention areactive herbicides. They should have utility for broad-spectrum pre-and/or post-emergence weed control in areas where complete control ofall vegetation is desired, such as around fuel storage tanks, ammunitiondepots, industrial storage areas, parking lots, drive-in theaters,around billboards, highway and railroad structures. Alternatively, manyof the subject compounds should be useful for the selective pre- orpost-emergence weed control in crops, such as wheat and cotton.

The rates of application for the compounds of the invention aredetermined by a number of factors, including their use as selective orgeneral herbicides, the crop species involved, the types of weeds to becontrolled, weather and climate, formulations selected, mode ofapplication, amount of foliage present, etc. In general terms, thesubject compounds should be applied at levels of around 0.001 to 5kg/ha, the lower rates being suggested for use on ligher soils and/orthose having a low organic matter content, for selective weed control orfor situations where only short-term persistence is required.

The compounds of the invention may be used in combination with any othercommercial herbicide examples of which are those of the triazine,triazole, uracil, urea, amide, diphenylether, carbamate and bipyridyliumtypes. They may also be used in combination with mefluidide.

The herbicidal properties of the subject compounds were discovered in anumber of greenhouse tests. The test procedures and results follow.

Although some of the compounds do not exhibit a high degree of activityat the low rates tested, it is expected that these compounds willexhibit herbicidal effects at higher rates.

TEST A

Seeds of crabgrass (Digitaris sp.), barnyardgrass (Echinochloacrusgalli), wild oats (Avena fatua), sicklepod (Cassia obtusifolia),morningglory (Ipomoea sp.), cocklebur (Xanthium sp.), sorghum, corn,soybean, cotton, sugar beet, rice, wheat and purple nutsedge (Cyperusrotundus) tubers were planted and treated pre-emergence with thechemicals dissolved in a non-phytotoxic solvent. At the same time, thesecrop and weed species were treated with a soil/foliage application. Atthe time of treatment, the plants ranged in height from 2 to 18 cm.Treated plants and controls were maintained in a greenhouse for sixteendays, after which all species were compared to controls and visuallyrated for response to treatment. The ratings, summarized in Table A, arebased on a numerical scale extending from 0=no injury, to 10=completekill. The accompanying descriptive symbols have the following meanings:

B=burn;

C=chlorosis or necrosis;

E=emergence inhibition;

G=growth retardation;

H=formative effects; and

U=unusual pigmentation. ##STR92##

    TABLE A       Cmpd. 1 Cmpd. 2 Cmpd. 3 Cmpd. 4 Cmpd. 5 Cmpd. 6 Cmpd. 7 Cmpd. 8 Cmpd.     9 Cmpd. 10 Cmpd. 11 Cmpd. 12 Cmpd. 13 Cmpd. 14 Cmpd. 15 Rate kg/ha 0.05     0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05     0.05      POST-EMERGENCE Morningglory 9C 2C,4H 4C,8H 0 5C,9G 6C,9G 2C,2H 4     C,9H 2C,4H 9C 2C,7G 3C,7G 2C,4H 1C 0 Cocklebur 9C 1C,2G 4C,9H 0 5C,9H     6C,9H 1C 5C,9H 1C 9C 2C,8H 2C,5G 5G 1C,7G 0 Sicklepod 2C,4G 1C 3C,3H 0     2C,3H 5C,6G 0 3C,3H 1C 4C,8G 3G 2G 1C 2C,5G 5G Nutsedge 1C 0 2C,8G 0     3C,9G 6C,9G 0 3C,8G 0 10C 9G 0 2C,8G 2C,5G 2G Crabgrass 1C 0 2C,7G 0 3H     5G 0 4G 0 6C,9G 3G 2G 1C,3H 9C 0 Barnyardgrass 3C,8H 0 9C 0 9C 9C 1H 1H     0 9C 3C,9H 3C,8H 2C,8H 9C 4C,9H Wild Oats 2C,4G 0 6C,9H 0 4C,8G 5C,9G 0     5C,9G 0 9C 3C,5G 0 1C 4C,8G 0 Wheat 3C,8G 0 5C,9G 0 5C,9G 9C 0 6C,9G 0     9C 0 3G 1C 3C,9G 0 Corn 2C,9H 0 2C,9H 0 6C,9H 5C,9G 0 4C,9H 0 5U,9C     3C,9G 0 5C,9G 3C,9G 0 Soybean 3C,9G 4G 3C,8H 0 4C,9G 4C,9G 0 4C,9G 1C 9C     3C,7H 2H 1C 2C,9G 1H Rice 4C,9G 3G 4C,9G 0 6C,9G 5C,9G 0 5C,9G 0 9C     4C,9G 2C,7G 4G 5C,9G 2C,7G Sorghum 2C,9G 2G 4C,9G 0 4C,9G 6C,9G 2C,5G     4C,9G 1C 9C 2C,9G 3C,9H 2C,9G 4C,9G 2C,8G Sugar beet 9C 2C,7G 4C,8H 0 9C     9C 3C,7G 9C 2G 9C 2C,5H 4G 2C,3H 1C,4G 1C Cotton 3C,9H 0 4C,9H 0 2C,8H     4C,9H 2C,5G 3C,7H 0 10C 2C,3H 5G 1C,5G 5C,9G 1C       Cmpd. 16 Cmpd. 17 Cmpd. 18 Cmpd. 19 Cmpd. 20 Cmpd. 21 Cmpd. 22     Compound 23 Cmpd. 24 Cmpd. 25 Cmpd. 26 Cmpd. 27 Cmpd. 28 Cmpd. 29 Rate     kg/ha 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.4 0.05 0.05 0.05 0.05 0.05     0.05 0.05       POST-EMERGENCE Morningglory 2C,5G 0 0 0 2C,6G 2C,5H 3G 2C,3H 1C 1C     2C,7G 3C,3H 10C 2C,7G 2G Cocklebur 2C,6G 0 1C 2H 10C 9C 7H 5C,9G 6H 10C     10C 9C 10C 9C 2C,8G Sicklepod 0 0 0 0 3C,9G 3C,8G 2C,8G 0 1C 2C 2C,3G 3G     5C,9G 5C,9G 2C Nutsedge 0 0 0 0 3C,7G 8G 2C,9G 6G 0 0 5G 5G 2C,8G 9G 4G     Crabgrass 2G 2G 2G 4G 5G 3C,6G 2C,5G 6G 2G 5G 2C,8G 2C,5G 3C,8G 2C,4G 0     Barnyardgrass 2C,7H 3H 3C,8H 4C,8H 3C,9H 5C,9H 5C,9H 2C,8H 4H 3C,9H     5C,9H 5C,9H 5C,9H 5C,9H 3C,9H Wild Oats 1C 0 0 0 2C,9G 2C,9G 3C,9G 0 0     2C,8G 2C,9G 2C,6G 3C,9G 2C,6G 0 Wheat 8G 3G 0 0 7G 9C 9G 0 0 6G 2C,9G     2C,8G 6G 5G 0 Corn 1C,1H 2C,3H 2C,6H 1C 9G 3C,9H 9G 2H 0 5U,9G 5U,9C     3C,9H 3C,9G 3C,9G 4C,9H Soybean 2C,2H 4G 2C,5H 1C 3C,8G 3C,8G 4C,9G     1C,3G 1H 2C,8G 9C 9C 5C,9G 4C,9G 3C,7H Rice 2C,8G 2C,8G 3C,9G 2C,7G     5C,9G 5C,9G 5C,9G 3C,5G 2C,3G 5C,9G 9C 5C,9G 5C,9G 3C,9G 2C,8G Sorghum     2C,7G 3C,7G 2C,8G 2C,7G 2C,9G 2C,9H 1U,9G 8H 5G 4C,9G 9C 2C,9G 3C,9G     4C,9G 3C,9H Sugar beet 2C 0 2H 1C 4C,9G 2C,5G 3G 3C,8H 2C,5G 3C,8H 5C,9G     3C,6H 9C 9C 9C Cotton 2C,3H 0 1C 1C 3C,6G 4C,8G 3C,8H 2G 2G 3C,8H 10C     2C,9G 5C,9G 3C,8G 4C,6G        Cmpd. 30 Cmpd. 31 Cmpd. 32 Cmpd. 33 Cmpd. 34 Cmpd. 35 Cmpd. 36 Cmpd.     37 Cmpd. 38 Cmpd. 39 Rate kg/ha 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05     0.05 0.05       POST-EMERGENCE Morningglory 3C,8H 9C 3C,7H 2C,5G 3G 4C,9G 2C,6G 10C     5C,9G 9C Cocklebur 9C 9C 5C,9G 3C,9H 8G 9C 9H 9C 9C 5C,9G Sicklepod     2C,2H 4C,8G 2C,4G 2C,5G 1C 9C 8H 9C 9C 5C,9G Nutsedge 2C,6G 9G 5G 3G 3G     10C 5G 10C 9C 9G Crabgrass 2C,5G 2C,7G 5G 3G 2G 3C,7G 4G 6G 2G 3C,9G     Barnyardgrass 3C,9H 5C,9H 9H 9H 3C,9H 5C,9G 9H 9C 5C,9H 9C Wild Oats     2C,5G 4C,8G 0 0 0 4C,9G 3G 9C 2C,5G 6C,9G Wheat 5G 7G 0 0 0 4C,9G 3G     4C,9G 2C,6G 6C,9G Corn 2C,9H 2C,8G 2C,9H 3C,9H 3C,8H 4C,9G 2C,9G 5C,9G     9G 3U,9G Soybean 4C,9G 3C,9G 4C,9G 5C,9G 3C,9G 9C 2C,8G 9C 4C,9G 5C,9G     Rice 4C,9G 5C,9G 4C,9G 3C,8G 2C,7G 5C,9G 4C,9G 9C 5C,9G 6C,9G Sorghum     3C,9H 5C,9G 2C,9G 4C,9G 2C,7G 9C 3C,9G 9C 2C,9G 5C,9H Sugar beet 3C,7H     9C 9C 4C,9G 3C,8G 9C 9C 9C 9C 5C,9G Cotton 3C,6G 4C,8G 3C,8H 3G 2G 9C     3C,8G 9C 5C,9G 9C        Cmpd. 1 Cmpd. 2 Cmpd. 3 Cmpd. 4 Cmpd. 5 Cmpd. 6 Cmpd. 7 Cmpd. 8 Cmpd.     9 Cmpd. 10 Cmpd. 11 Cmpd. 12 Cmpd. 13 Cmpd. 14 Cmpd. 15 Rate kg/ha 0.05     0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05     0.05      PRE-EMERGENCE Morningglory 2C,8H 0 1C 0 4C,9G 9G 1C 3C,8H 0 9H 8     H 7H 6G 2C,7H 0 Cocklebur 2C,8H 0 0 0 3C,8H 8H 1H 1C 0 3C,9H 9H 8G 9H 8H     -- Sicklepod 0 0 0 0 3C 3C 0 1C 0 5C,9G 5G 0 2G 2C,7G -- Nutsedge 1C 0 0     0 3C,8G 3C,9G 0 3C,5G 0 10E 8G 0 0 2C,5G 0 Crabgrass 0 0 0 0 0 3G 0 1C 0     5C,9G 0 0 0 2C,8H 0 Barnyardgrass 2H 0 0 0 5C,9H 5C,9H 0 2C,4H 0 5C,9H     3C,3H 0 2C,3H 4C,8H 2C Wild Oats 2C 0 0 0 3C,6G 5C,9G 0 3C,8H 0 6C,9H     2C,8G 2C,7G 2C,7G 4C,9G 1C Wheat 2G 0 0 0 3C,9H 2C,9H 0 2G 0 10E 2C,8G 0     2C,5G 4C,9H 2G Corn 2C,8H 0 2C,9H 0 3C,9H 3C,9H 0 3C,9H 0 10E 9G 5G     3C,9H 9H 4G Soybean 1H 0 0 0 3C,8H 2C,5H 0 3C,3H 0 9H 4C,6H 0 2C,6H     2C,2H 0 Rice 0 0 3G 0 9H 10E 0 3C,7G 0 10E 5C,9H 8G 3C,7H 10H 0 Sorghum     3C,9H 0 2C,9H 0 5C,9H 5C,9H 2C,5G 3C,9H 0 10H 9H 6H 3C,9H 9C 2C,4G Sugar     beet 5C,9G 2H 5C,9G 0 5C,9G 9C 2G 9C 0 10E 4C,8G 6G 8G 9G 0 Cotton 5G 0     1C 0 2C,5G 2C,9G 0 3C,7G 0 9G 8G 3G 6G 8G 0       Cmpd. 16 Cmpd. 17 Cmpd. 18 Cmpd. 19 Cmpd. 20 Cmpd. 21 Cmpd. 22     Compound 23 Cmpd. 24 Cmpd. 25 Cmpd. 26 Cmpd. 27 Cmpd. 28 Cmpd. 29 Rate     kg/ha 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.4 0.05 0.05 0.05 0.05 0.05     0.05 0.05       PRE-EMERGENCE Morningglory 0 0 0 0 9G 8G 5G 2G 2H -- 6H 0 9G 8G 3C,9G     Cocklebur -- 0 -- 0 8G 7H 8G 2H 6G 8H 9H 6H 8G 9G -- Sicklepod 0 0 0 0     7G 0 8G 2G 0 5G 5G 0 9G 8G 9G Nutsedge 0 0 0 0 8G 4G 10E 2G 0 7G 5G 0 9G     8G 5G Crabgrass 0 0 0 0 6G 6G 5G 0 0 5G 5G 2G 7G 2G 2G Barnyardgrass 1C     0 1C 2C 6H 8G 6G 3C,3H 1C 2C,8G 5C,9H 2C,8H 9H 9G 8G Wild Oats 2G 0 1C     1C 7G 3C,7G 5G 2G 0 2C,8G 8G 2C,8G 2C,8G 2C,8G 7G Wheat 7G 0 2G 3G 7G     2C,9H 4G 0 0 2C,8G 8G 6G 3C,9G 2C,8G 6G Corn 2C,3G 2G 2C,6G 1H 2C,8G     2C,8H 2C,8G 3G 1C 3C,9G 2C,9G 3C,7G 3C,9G 8G 2C,8G Soybean 0 0 1C 0 2H 0     0 0 0 2H 5H 3H 3C,6H 2C,4H 3C,5H Rice 0 0 0 1C 10E 10E 9H 6G 0 2C,9H     3C,8H 2C,8G 9H 9H 2C,8G Sorghum 2C,6G 3C,5G 2C,5G 3C,7G 4C,9H 2C,9G     2C,8G 8G 3G 2C,9H 5C,9H 2C,9G 3C,9G 2C,8G 3C,8H Sugar beet 4G 2H 2H 2H     5G 7G 3G 8G 3H 2C,8G 10E 3C,8G 4C,9G 3C,9G 3C,8G Cotton 0 0 0 0 5G 2G 7G     4G 0 7G 9G 2G 9G 8G 8G        Cmpd. 30 Cmpd. 31 Cmpd. 32 Cmpd. 33 Cmpd. 34 Cmpd. 35 Cmpd. 36 Cmpd.     37 Cmpd. 38 Cmpd. 39 Rate kg/ha 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05     0.05 0.05       PRE-EMERGENCE Morningglory 2G 9G 9G 0 3G 9G 8G 9G 7G 9G Cocklebur --     9H 9H 9H -- -- -- 9H 7G 9H Sicklepod 6G 8G 8G 0 0 9G 9G 9C 7G 9G     Nutsedge 4G 5G 0 0 0 10E 0 10E 10E 10E Crabgrass 2G 4G 2G 0 0 8G 0 3C,8G     0 4C,9G Barnyardgrass 3C,8G 8G 8G 2H 0 5C,9H 2C,8H 5C,9H 1C 3C,9H Wild     Oats 2C,7G 2C,7G 2C,8G 0 0 5C,9G 7G 6C,9G 5G 4C,9G Wheat 7G 5C,9G 7G 0 0     10E 8G 6C,9H 4G 5C,9H Corn 8G 2C,8G 8G 0 0 10H 3C,9G 4C,9G 4G 9G Soybean     2C,2H 3C,6G 4C,5H 0 1H 9H 3C,8H 9G 2G 9H Rice 4C,9H 8G 7G 0 0 10E 8H 10E     9H 10E Sorghum 2C,8G 2C,9G 2C,9G 0 0 5C,9H 3C,9G 7C,9H 4G 5C,9G Sugar     beet 2C,7G 3C,8G 9C 5G 2G 9C 9G 6C,9G 5G 5C,9G Cotton 6G 8G 8G 0 -- 9G     9C 9G 8G 9G

TEST B Post-emergence

Two round pans (25 cm diameter by 12.5 cm deep) were filled withWoodstown sandy loam soil. One pan was planted with blackgrass(Alopecurus myosuroides), sugarbeets, nutsedge (Cyperus rotundus)tubers, crabgrass (Digitaria sanguinalis), sicklepod (Cassiaobtusifolia), teaweed (Sida spinosa), jimsonweed (Datura stramonium),velvetleaf (Abutilon theophrasti), and giant foxtail (Setaria faberii).The other pan was planted with wheat, cotton, rice, corn, soybean, wildoats (Avena fatua), cocklebur (Xanthium pensylvanicum), morningglory(Ipomoea hederacea), Johnsongrass (Sorghum halepense) and barnyardgrass(Echinochloa crusgalli). The plants were grown for approximatelyfourteen days, then sprayed post-emergence with the chemicals dissolvedin a non-phytotoxic solvent.

Post-emergence

Two round pans (25 cm diameter by 12.5 cm deep) were filled withWoodstown sandy loam soil. One pan was planted with blackgrass,sugarbeets, nutsedge, crabgrass, sicklepod, teaweed, jimsonweed,velvetleaf and giant foxtail. The other pan was planted with wheat,cotton, rice, corn, soybean, wild oats, cocklebur, morningglory,johnsongrass and barnyardgrass. The two pans were sprayed pre-emergencewith the chemicals dissolved in a non-phytotoxic solvent.

Treated plants and controls were maintained in the greenhouse for 28days, then all treated plants were compared to controls and visuallyrated for plant response. The rating system was as described for Test A.

The data show that several of the compounds tested have utility forselective weed control in crops such as wheat and cotton.

                                      TABLE B                                     __________________________________________________________________________                                                             Compound                     Compound 1  Compound 3                                                                           Compound 5 Compound 6 Compound                                                                              10                   Rate g/ha                                                                             250                                                                              62 16 4  62 16                                                                              4 250                                                                              62 16 4 250                                                                              62 16 4 62 16 4 62 16                __________________________________________________________________________    Post-Emergence                                                                Corn    9G 7G 4G 2G 8G 5G                                                                              0 10C                                                                              10C                                                                              9G 5G                                                                              10C                                                                              10C                                                                              10G                                                                              5G                                                                              9G 3G 0 10G                                                                              10C               Wheat   0  0  0  0  9G 5G                                                                              0 10C                                                                              9C 3G 0 10C                                                                              10G                                                                              6G 0 6G 4G 0     10C                                                                     10C                    Rice    5G 2G 0  0  9G 6G                                                                              4G                                                                              10C                                                                              10G                                                                              6G 0 10C                                                                              10C                                                                              10C                                                                              7G                                                                              8G 3G 0     10C                                                                     10C                    Soybeans                                                                              10G                                                                              9G 9G 7G 9G 8G                                                                              3G                                                                              10G                                                                              10G                                                                              10G                                                                              6G                                                                              10G                                                                              10G                                                                              10G                                                                              5G                                                                              9G 8G 4G    10G                                                                     10G                    Cotton  10C                                                                              10C                                                                              10C                                                                              10G                                                                              6G 0 0 6G 3G 0  0 10G                                                                              10G                                                                              9G 5G                                                                              5G 0  0     10C                                                                     10G                    Sugar beets                                                                           10C                                                                              10C                                                                              10C                                                                              10C                                                                              10G                                                                              9G                                                                              3G                                                                              10C                                                                              10C                                                                              10C                                                                              5G                                                                              10C                                                                              10C                                                                              10C                                                                              8G                                                                              10C                                                                              8G 3G    10C                                                                     10G                    Crabgrass                                                                             5G 2G 0  0  8G 4G                                                                              2G                                                                              7G 2G 0  0 10C                                                                              8G 4G 0 0  0  0     10C                                                                     9G                     Johnsongrass                                                                          7G 6G 3G 0  9G 8G                                                                              2G                                                                              10C                                                                              10C                                                                              0  0 10C                                                                              10C                                                                              6G 3G                                                                              10G                                                                              10G                                                                              4G    10C                                                                     10C                    Blackgrass                                                                            8G 6G 4G 0  8G 5G                                                                              0 10C                                                                              10C                                                                              0  0 10C                                                                              10C                                                                              10G                                                                              5G                                                                              4G 0  0     10C                                                                     10C                    Barnyardgrass                                                                         2G 0  0  0  9G 4G                                                                              0 10C                                                                              10C                                                                              9G 3G                                                                              10C                                                                              10C                                                                              7G 2G                                                                              0  0  0     10G                                                                     10C                    Nutsedge                                                                              10C                                                                              10C                                                                              9C 6C 8G 4G                                                                              0 9C 9C 4G 0 10C                                                                              10C                                                                              9C 3G                                                                              0  0  0     10C                                                                     9C                     Giant foxtail                                                                         -- -- -- -- -- --                                                                              --                                                                              10C                                                                              10C                                                                              7G 4G                                                                              10C                                                                              7G 5G 2G                                                                              3G 0  0     10C                                                                     10G                    Wild Oats                                                                             0  0  0  0  9G 2G                                                                              0 9C 5G 0  0 10C                                                                              9G 6G 0 9G 5G 0     10C                                                                     10C                    Cocklebur                                                                             10C                                                                              10C                                                                              10C                                                                              10G                                                                              10G                                                                              3G                                                                              0 10C                                                                              10G                                                                              10G                                                                              7G                                                                              10G                                                                              10G                                                                              9G 8G                                                                              9G 8G 2G    10G                                                                     10G                    Morningglory                                                                          10C                                                                              10C                                                                              10C                                                                              10C                                                                              7G 4G                                                                              2C                                                                              10C                                                                              10G                                                                              8G 3G                                                                              10G                                                                              10G                                                                              9G 6G                                                                              8G 6G 0     10G                                                                     9G                     Teaweed 10G                                                                              10G                                                                              10G                                                                              6G 10G                                                                              4G                                                                              0 5G 0  0  0 10G                                                                              6G 4G 0 3G 0  0     10G                                                                     7G                     Sicklepod                                                                             10G                                                                              10G                                                                              10G                                                                              7G 7G 2G                                                                              0 6G 2G 0  0 10G                                                                              7G 3G 3G                                                                              3G 0  0     10G                                                                     10G                    Jimsonweed                                                                            10C                                                                              10C                                                                              10G                                                                              7G 10G                                                                              7G                                                                              5G                                                                              10G                                                                              10G                                                                              5G 3G                                                                              10C                                                                              10G                                                                              10G                                                                              7G                                                                              9G 6G 2G    9G                                                                      5G                     Velvetleaf                                                                            10C                                                                              10C                                                                              10C                                                                              9G 6G 3G                                                                              0 3G 0  0  0 10C                                                                              10G                                                                              8G 4G                                                                              4G 0  0     10C                                                                     8G                     __________________________________________________________________________                            Compound 10                                                                          Compound 14                                                                             Compound 24                                                                             Compound 37                                Rate g/ha                                                                             4   1  250                                                                              62 16                                                                              4 250                                                                              62 16                                                                              4 62 16 4  1                 __________________________________________________________________________                     Post-Emergence                                                               Corn    7G  4G 10B                                                                              10G                                                                              4G                                                                              0 10C                                                                              10C                                                                              9G                                                                              7G                                                                              10C                                                                              10G                                                                              10C                                                                              5G                                Wheat   6G  0  5G 0  0 0 0  0  0 0 7G 3G 0  0                                 Rice    10G 10C                                                                              9B 8G 7G                                                                              3G                                                                              10G                                                                              9G 8G                                                                              4G                                                                              10G                                                                              9G 6G 2G                                Soybeans                                                                              8G  3G 10G                                                                              8G 3G                                                                              0 9G 7G 3G                                                                              0 10G                                                                              10G                                                                              10G                                                                              6G                                Cotton  6G  2G 9G 8H 2G                                                                              0 7G 4G 0 0 10G                                                                              10G                                                                              5G 2G                                Sugar beets                                                                           8G  5G 9B 4G 2G                                                                              0 9G 8G 4G                                                                              0 10C                                                                              10C                                                                              10C                                                                              10C                               Crabgrass                                                                             5G  3G 10B                                                                              3G 0 0 2G 0  0 0 8G 4G 2G 0                                 Johnsongrass                                                                          10C 4G 10B                                                                              8B 3G                                                                              0 8G 3G 0 0 10C                                                                              10C                                                                              6G 3G                                Blackgrass                                                                            9G  8G 9B 9B 3G                                                                              0 6G 2G 0 0 10C                                                                              9G 4G 2G                                Barnyardgrass                                                                         10C 4G 9B 8B 4G                                                                              2G                                                                              7G 7G 7G                                                                              5G                                                                              10C                                                                              10C                                                                              5G 2G                                Nutsedge                                                                              5G  0  5G 2G 0 0 0  0  0 0 10C                                                                              10C                                                                              9G 4G                                Giant foxtail                                                                         4G  0  9B 6G 2G                                                                              0 9G 7G 2G                                                                              0 10G                                                                              7G 3G 0                                 Wild Oats                                                                             6G  4G 4G 0  0 0 0  0  0 0 8G 2G 0  0                                 Cocklebur                                                                             8G  3G 8G 4G 2G                                                                              0 9G 9G 9G                                                                              6G                                                                              9G 7G 2G 0                                 Morningglory                                                                          4G  0  9G 2C 0 0 2C 2G 0 0 10G                                                                              10G                                                                              9G 5G                                Teaweed 2G  0  2C 0  0 0 4G 2G 0 0 9G 6G 3G 0                                 Sicklepod                                                                             10G 5G 2G 0  0 0 2G 0  0 0 10C                                                                              9G 4G 0                                 Jimsonweed                                                                            2G  0  4G 2G 0 0 0  0  0 0 10G                                                                              9G 9G 7G                                Velvetleaf                                                                            7G  2G 8G 4G 2G                                                                              0 8G 6G 3G                                                                              0 10C                                                                              10C                                                                              8G 3G                __________________________________________________________________________                                                               Com-                                                                          pound                      Compound 1                                                                           Compound 3                                                                           Compound 5                                                                            Compound 6 Compound 8                                                                           Compound                                                                                 11                 Rate g/ha                                                                             250 62 62  16 250                                                                              62 16                                                                              250                                                                              62 16 4 62  16 62 16 4  1 250                __________________________________________________________________________    Pre-Emergence                                                                 Corn    7G  4G 0   0  10G                                                                              2G 0 10E                                                                              10G                                                                              3G 0 8G  2G 10G                                                                              10G                                                                              8G 2G                                                                              7G                 Wheat   0   0  2G  0  9G 7G 3G                                                                              9G 7G 3G 0 0   0  10G                                                                              10G                                                                              5G 3G                                                                              5G                 Rice    10G 7G 7G  3G 10E                                                                              10G                                                                              5G                                                                              10E                                                                              10E                                                                              10E                                                                              7G                                                                              8G  2G 10E                                                                              10E                                                                              10E                                                                              9G                                                                              8G                 Soybean 8G  4G 2C  0  9G 2G 0 8G 5G 2G 0 4G  0  9G 6G 4G 0 6G                 Cotton  10G 7G 0   0  0  0  0 3G 2G 0  0 0   0  9G 4G 2G 0 2G                 Sugar beets                                                                           10G 9G 7G  0  10G                                                                              10G                                                                              5G                                                                              10E                                                                              10E                                                                              10E                                                                              3G                                                                              9G  3G 10G                                                                              10G                                                                              8G 3G                                                                              9G                 Crabgrass                                                                             6G  3G 4G  0  10G                                                                              4G 0 9G 8G 5G 0 3G  0  10G                                                                              10G                                                                              5G 0 2G                 Johnsongrass                                                                          6G  5G 7G  4G 10G                                                                              8G 2G                                                                              10C                                                                              9G 8G 2G                                                                              9G  3G 10C                                                                              10G                                                                              9G 3G                                                                              7G                 Blackgrass                                                                            8G  6G 3G  2G 0  0  0 10E                                                                              10E                                                                              7G 3G                                                                              0   0  10E                                                                              10E                                                                              10G                                                                              5G                                                                              9G                 Barnyardgrass                                                                         4G  2G 4G  2G 10G                                                                              7G 4G                                                                              10G                                                                              10G                                                                              3G 0 4G  0  10G                                                                              10G                                                                              8G 2G                                                                              3G                 Nutsedge                                                                              10E 8G 3G  0  8G 2G 0 10E                                                                              10E                                                                              5G 0 0   0  10E                                                                              10E                                                                              5G 0 8G                 Giant foxtail                                                                         10E 4G 8G  6G 9G 9G 3G                                                                              10E                                                                              10G                                                                              3G 0 0   0  10E                                                                              10G                                                                              10G                                                                              4G                                                                              2G                 Wild Oats                                                                             0   0  3G  0  9G 5G 3G                                                                              10G                                                                              8G 5G 3G                                                                              3G  0  9G 8G 5G 3G                                                                              3G                 Cocklebur                                                                             10G 8G 4G  0  6G 2G 0 10G                                                                              7G 2G 0 0   0  10G                                                                              9G 5G 0 2G                 Morningglory                                                                          10G 7G 0   0  3G 0  0 3G 4G 0  0 0   0  9G 6G 2G 0 3G                 Teaweed 9G  7G 5G  3G 6G 4G 0 10G                                                                              5G 0  0 2G  0  9G 5G 0  0 4G                 Sicklepod                                                                             9G  6G 7G  4G 10E                                                                              3G 0 10E                                                                              6G 2G 0 3G  0  10E                                                                              10E                                                                              4G 0 0                  Jimsonweed                                                                            10G 9G 2G  0  8G 4G 0 10G                                                                              7G 3G 0 0   0  10G                                                                              8G 5G 0 8G                 Velvetleaf                                                                            10G 8G 0   0  7G 3G 0 10G                                                                              8G 3G 0 0   0  10G                                                                              10G                                                                              7G 0 5G                 __________________________________________________________________________                                    Compound 11                                                                          Compound 14                                                                             Compound                                                                             Compound 37                                   Rate g/ha                                                                             62  16 250                                                                              62 16                                                                              4 250 62 62 16                                                                              4                __________________________________________________________________________                            Pre-Emergence                                                                 Corn    2G  0  8G 5G 2C                                                                              0 6G  2G 8G 4G                                                                              0                                        Wheat   2G  0  6G 3G 0 0 2G  0  5G 3G                                                                              0                                        Rice    7G  5G 10G                                                                              10G                                                                              6G                                                                              2C                                                                              6G  4G 10G                                                                              9G                                                                              5G                                       Soybean 2C  0  6C 4G 3G                                                                              2G                                                                              2G  0  10G                                                                              5G                                                                              2G                                       Cotton  0   0  3C 0  0 0 3G  2G 8G 4G                                                                              0                                        Sugar beets                                                                           4G  2G 5G 2G 0 0 4G  2G 10G                                                                              4G                                                                              0                                        Crabgrass                                                                             0   0  9G 9G 3G                                                                              0 5G  3G 7G 2G                                                                              0                                        Johnsongrass                                                                          4G  2G 9G 5G 0 0 8G  4G 10G                                                                              8G                                                                              2G                                       Blackgrass                                                                            5G  3G 9G 6G 3C                                                                              0 5G  2G 10G                                                                              8G                                                                              3G                                       Barnyardgrass                                                                         0   0  9G 5G 0 0 5G  2G 9G 6G                                                                              2G                                       Nutsedge                                                                              6G  2G 6G 3G 2C                                                                              0 4G  2G 9G 4G                                                                              2G                                       Giant foxtail                                                                         0   0  9G 5G 0 0 6G  2G -- --                                                                              --                                       Wild Oats                                                                             0   0  5G 2G 0 0 4G  2G 3G 0 0                                        Cocklebur                                                                             0   0  6G 4G 2G                                                                              0 5G  2G 9G 2G                                                                              0                                        Morningglory                                                                          0   0  7C 3C 2G                                                                              0 4G  2G 5G 2G                                                                              0                                        Teaweed 2G  0  6G 3G 0 0 5G  3G 9G 3G                                                                              0                                        Sicklepod                                                                             0   0  5G 2G 0 0 2G  0  8G 4G                                                                              2G                                       Jimsonweed                                                                            5G  2G 3G 2G 0 0 4G  2G 9G 2G                                                                              0                                        Velvetleaf                                                                            2G  0  7G 4G 2G                                                                              0 5G  3G 9G 6G                                                                              0                __________________________________________________________________________

What is claimed is:
 1. A compound of the formula: ##STR93## wherein R is H or CH₃ ;L is ##STR94## R₁ is C₁ -C₄ alkyl, C₁ -C₄ alkoxy, OCH₂ CH₂ OCH₃, F, Cl, Br, NO₂, CF₃, CO₂ R₁₅, SO₂ NR₁₆ R₁₇, SO₂ N(OCH₃)CH₃, OSO₂ R₁₈, S(O)_(n) R₁₉, WCF₃, WCHF₂, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₆ H₅, C₁ -C₂ alkyl substituted with OCH₃ or OCH₂ CH₃, ##STR95## R₂ is H, F, Cl, Br, CF₃, CH₃, OCH₃ or SCH₃ ; R₁₅ is C₁ -C₄ alkyl, CH₂ CH₂ OCH₃, CH₂ CH₂ Cl or CH₂ CH═CH₂ ; R₁₆ is C₁ -C₂ alkyl; R₁₇ is C₁ -C₂ alkyl; R₁₈ is C₁ -C₃ alkyl or N(CH₃)₂ ; R₁₉ is C₁ -C₃ alkyl or CH₂ CH═CH₂ ; and W is O, S or SO₂ ; A is ##STR96## X is CH₃, OCH₃, OC₂ H₅, F, Cl, Br, CF₃ or OCHF₂ ; T is H, SeCH₃, SeC₆ H₅, SCH₃ or ##STR97## Y is SeCH₃, SeO₆ H₅, ##STR98## OSi(CH₃)₃, CH₂ OH or CH₂ OSi(CH₃)₃ ; Z is CH; R₂₀ is H, CH₃, CF₃, OCH₃, F, Cl, Br or NO₂ ; p is 0, 1 or 2; and q is 0, 1 or 2; provided that the sum of p and q is less than or equal to 2; and their agriculturally suitable salts.
 2. A compound of claim 1 wherein R is H.
 3. A compound of claim 2 wherein R₂ is H, R₂₀ is H, X is CH₃ or OCH₃, T is H, p is 0 and q is
 0. 4. A compound of claim 3 wherein R₁ is C₁ -C₂ alkyl, C₁ -C₂ alkoxy, Cl, NO₂, CO₂ CH₃, CO₂ C₂ H₅, SO₂ N(CH₃)₂, SO₂ CH₃, OSO₂ CH₃ or WCHF₂.
 5. The compound of claim 1 which is 2-[[[4-methoxy-6-(phenoxymethyl)pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoic acid, methyl ester.
 6. The compound of claim 1 which is 2-[[[4-methoxy-6-(methylselenylmethyl)pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoic acid, methyl ester.
 7. The compound of claim 1 which is 2-[[[4-methoxy-6-(phenylthiomethyl)pyrimidin-2-yl]aminocarbonyl]aminosulfonyl]benzoic acid, methyl ester.
 8. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 1 and at least one of the following: surfactant, solid or liquid inert diluent.
 9. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 2 and at least one of the following: surfactant, solid or liquid inert diluent.
 10. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 3 and at least one of the following: surfactant, solid or liquid inert diluent.
 11. A composition suitable for controlling the growth of undesired vegetation wich comprises an effective amount of a compound of claim 4 and at least one of the following: surfactant, solid or liquid inert diluent.
 12. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 1. 13. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 2. 14. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 3. 15. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 4. 